IFI27: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of IFI27. The page also collects GeneMedi's different modalities and formats products for IFI27 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the IFI27 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; identical protein binding activity; and lamin binding activity. Involved in several processes, including cellular protein metabolic process; defense response to other organism; and extrinsic apoptotic signaling pathway. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of protein export from nucleus. Located in mitochondrial membrane and nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-IP0997 |
| Target Name | IFI27 |
| Gene ID | 3429,700513 |
| Gene Symbol and Synonyms | FAM14D,IFI27,ISG12,ISG12A,P27 |
| Uniprot Accession | P40305 |
| Uniprot Entry Name | IFI27_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Ovary Cancer |
| Gene Ensembl | ENSG00000165949 |
| Target Classification | N/A |
Pre-made anti-IFI27 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-IFI27 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IFI27 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-IFI27 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species IFI27/ FAM14D/ ISG12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFI27 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| IFI27 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made IFI27 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMAP000314 | Human IFI27 Adenovirus plasmid | BC015492 | Human | Adenovirus plasmid | Detail |
| pGMLP000465 | human IFI27 Lentivirus plasmid | NM_005532 | Human | Lentivirus plasmid | Detail |
| vGMLP000465 | human IFI27 Lentivirus particle | NM_005532 | Human | Lentivirus particle | Detail |
| vGMAP000314 | Human IFI27 Adenovirus particle | BC015492 | Human | Adenovirus particle | Detail |
| pGMLPm001016 | mouse Ifi27 Lentivirus plasmid | NM_194067.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001016 | mouse Ifi27 Lentivirus particle | NM_194067.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.