HNRNPK: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HNRNPK. The page also collects GeneMedi's different modalities and formats products for HNRNPK in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HNRNPK target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]
| Target ID | GM-IP0974 |
| Target Name | HNRNPK |
| Gene ID | 3190,15387,117282,709112,100855638,101099911,528135,100052735 |
| Gene Symbol and Synonyms | AUKS,CSBP,HNRNPK,HNRPK,KBBP,NOVA,TUNP |
| Uniprot Accession | P61978,P61980,Q3T0D0 |
| Uniprot Entry Name | HNRPK_HUMAN,HNRPK_RAT,HNRPK_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000165119 |
| Target Classification | N/A |
Pre-made anti-HNRNPK inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HNRNPK monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HNRNPK mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HNRNPK monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species HNRPK/ HNRNPK/ AUKS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNRNPK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HNRNPK protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HNRNPK viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP001524 | human HNRNPK Lentivirus particle | NM_031262 | Human | Lentivirus particle | Detail |
| pGMLP001524 | human HNRNPK Lentivirus plasmid | NM_031262 | Human | Lentivirus plasmid | Detail |
| pGMLV000779 | Norway rat Hnrnpk Lentivirus plasmid | NM_057141.1 | Norway Rat | Lentivirus plasmid | Detail |
| pGMLPm001399 | mouse Hnrnpk Lentivirus plasmid | NM_001301341 | Mouse | Lentivirus plasmid | Detail |
| vGMLV000779 | Norway rat Hnrnpk Lentivirus particle | NM_057141.1 | Norway Rat | Lentivirus particle | Detail |
| vGMLPm001399 | mouse Hnrnpk Lentivirus particle | NM_001301341 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.