BNIP3L: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of BNIP3L. The page also collects GeneMedi's different modalities and formats products for BNIP3L in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the BNIP3L target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
Target ID | GM-IP0427 |
Target Name | BNIP3L |
Gene ID | 665,12177,140923,641440,608552,101099293,534615,100054317 |
Gene Symbol and Synonyms | BNIP3a,BNIP3L,D14Ertd719e,Nip3L,NIX,UV93 |
Uniprot Accession | O60238,Q3T013 |
Uniprot Entry Name | BNI3L_HUMAN,BNI3L_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | Cancer |
Gene Ensembl | ENSG00000104765 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-BNIP3L inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-BNIP3L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-BNIP3L mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-BNIP3L monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species BNI3L/ BNIP3L/ BNIP3a protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNIP3L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
BNIP3L protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made BNIP3L viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP000351 | human BNIP3L Lentivirus particle | NM_004331 | Human | Lentivirus particle | Detail |
pGMLP000351 | human BNIP3L Lentivirus plasmid | NM_004331 | Human | Lentivirus plasmid | Detail |
pGMAD000366 | rat Bnip3l Adenovirus plasmid | NM_080888.1 | Rat | Adenovirus plasmid | Detail |
pGMAD000477 | Norway rat Bnip3l Adenovirus plasmid | NM_080888.1 | Norway Rat | Adenovirus plasmid | Detail |
vGMAD000366 | rat Bnip3l Adenovirus particle | NM_080888.1 | Rat | Adenovirus particle | Detail |
vGMAD000477 | Norway rat Bnip3l Adenovirus particle | NM_080888.1 | Norway Rat | Adenovirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.