BNIP3L: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of BNIP3L. The page also collects GeneMedi's different modalities and formats products for BNIP3L in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the BNIP3L target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]

Target IDGM-IP0427
Target NameBNIP3L
Gene ID665,12177,140923,641440,608552,101099293,534615,100054317
Gene Symbol and SynonymsBNIP3a,BNIP3L,D14Ertd719e,Nip3L,NIX,UV93
Uniprot AccessionO60238,Q3T013
Uniprot Entry NameBNI3L_HUMAN,BNI3L_BOVIN
Protein Sub-locationIntrocelluar Protein
Category
DiseaseCancer
Gene EnsemblENSG00000104765
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-BNIP3L inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-BNIP3L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-BNIP3L mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-BNIP3L monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabDetail



Recombinant multi-species BNI3L/ BNIP3L/ BNIP3a protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNIP3L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
BNIP3L proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made BNIP3L viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP000351human BNIP3L Lentivirus particleNM_004331HumanLentivirus particleDetail
pGMLP000351human BNIP3L Lentivirus plasmidNM_004331HumanLentivirus plasmidDetail
pGMAD000366rat Bnip3l Adenovirus plasmidNM_080888.1RatAdenovirus plasmidDetail
pGMAD000477Norway rat Bnip3l Adenovirus plasmidNM_080888.1Norway RatAdenovirus plasmidDetail
vGMAD000366rat Bnip3l Adenovirus particleNM_080888.1RatAdenovirus particleDetail
vGMAD000477Norway rat Bnip3l Adenovirus particleNM_080888.1Norway RatAdenovirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.