VTCN1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of VTCN1. The page also collects GeneMedi's different modalities and formats products for VTCN1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the VTCN1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Target IDGM-IP0154
Target NameVTCN1
Gene ID79679,242122,295322,714123,483140,101086586,539919,100066328
Gene Symbol and SynonymsB7-H4,B7h.5,B7H4,B7S1,B7X,PRO1291,RGD1311204,VCTN1,VTCN1
Uniprot AccessionQ7Z7D3,Q501W4
Uniprot Entry NameVTCN1_HUMAN,VTCN1_RAT
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target, Immuno-oncology Target, INN Index
DiseaseOvary Cancer
Gene EnsemblENSG00000134258
Target ClassificationCheckpoint-Immuno Oncology


Pre-made VTCN1-specific INN-index biosimilar (antibody&conjugates)

Anti-VTCN1 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Cat No.Products Name (INN Index)INN Name Previous Name Target FormatDetail
GMP-Bios-ab-019Pre-Made Alsevalimab biosimilar, Whole mAb, Anti-VTCN1 Antibody: Anti-B7-H4/B7H4/B7S1/B7X/B7h.5/PRO1291/VCTN1 therapeutic antibodyAlsevalimabVTCN1Whole mAbDetail

Click to check more INN-indexed antibody & protein biosimilar



Pre-made anti-VTCN1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-VTCN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-VTCN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-VTCN1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species VTCN1/ B7-H4/ B7H4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VTCN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
VTCN1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made VTCN1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP004468human VTCN1 Lentivirus particleNM_024626HumanLentivirus particleDetail
pGMLP004468human VTCN1 Lentivirus plasmidNM_024626HumanLentivirus plasmidDetail
pGMLPm001035mouse Vtcn1 Lentivirus plasmidNM_178594MouseLentivirus plasmidDetail
vGMLPm001035mouse Vtcn1 Lentivirus particleNM_178594MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.