AIM2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of AIM2. The page also collects GeneMedi's different modalities and formats products for AIM2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the AIM2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
AIM2 is a member of the IFI20X /IFI16 family.? It plays a putative role in tumorigenic reversion and may control cell proliferation.? Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]
| Target ID | GM-IO004 |
| Target Name | AIM2 |
| Gene ID | 9447,383619,304987,719260,104971426,100057148 |
| Gene Symbol and Synonyms | AIM2,Gm1313,Ifi210,PYHIN4 |
| Uniprot Accession | O14862,Q91VJ1 |
| Uniprot Entry Name | AIM2_HUMAN,AIM2_MOUSE |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000163568 |
| Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
Pre-made anti-AIM2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-AIM2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-AIM2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-AIM2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species AIM2/ PYHIN4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AIM2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| AIM2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made AIM2 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP002226 | human AIM2 Lentivirus particle | NM_004833.2 | Human | Lentivirus particle | Detail |
| pGMLP002226 | human AIM2 Lentivirus plasmid | NM_004833.2 | Human | Lentivirus plasmid | Detail |
| pGMLPm003865 | mouse Aim2 Lentivirus plasmid | NM_001013779.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm003865 | mouse Aim2 Lentivirus particle | NM_001013779.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.