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Human CXCR4/CD184/D2S201E ORF/cDNA clone-Lentivirus particle (NM_001008540.2)
Cat. No.: vGMLV001389
Pre-made Human CXCR4/CD184/D2S201E Lentiviral expression plasmid for CXCR4 lentivirus packaging, CXCR4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLV001389 | Human CXCR4 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLV001389 |
| Gene Name | CXCR4 |
| Accession Number | NM_001008540.2 |
| Gene ID | 7852 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 1071 bp |
| Gene Alias | CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS |
| Fluorescent Reporter | Null |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | Null |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGTCCATTCCTTTGCCTCTTTTGCAGATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGCTAA |
| ORF Protein Sequence | MSIPLPLLQIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T96079 |
| Target Name | CXCR4/CD184 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
7852 |
| Gene ID |
100050974 (Equus caballus), 119863891 (Canis lupus familiaris), 12767 (Mus musculus), 281736 (Bos taurus) 493676 (Felis catus), 60628 (Rattus norvegicus), 707329 (Macaca mulatta), 7852 (Homo sapiens) |
| Gene Symbols & Synonyms | CXCR4,Cxcr4,CD184,LESTR,Sdf1r,CXC-R4,CXCR-4,Cmkar4,PB-CKR,b2b220Clo,PBSF/SDF-1,FB22,HM89,LAP3,LCR1,NPYR,WHIM,LAP-3,NPY3R,NPYRL,WHIMS,HSY3RR,NPYY3R,WHIMS1,D2S201E |
| Target Alternative Names | C-X-C chemokine receptor type 4,CD184,CXC-R4,CXCR-4,CXCR4,Cmkar4,Cxcr4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,LPS-associated protein 3),Leukocyte-derived seven transmembrane domain receptor (LESTR),Lipopolysaccharide-associated protein 3 (LAP-3,NPY3R,NPYR,NPYRL,NPYY3R,PB-CKR,PBSF/SDF-1,Sdf1r,Stromal cell-derived factor 1 receptor (SDF-1 receptor),WHIM,WHIMS,WHIMS1,b2b220Clo |
| Uniprot Accession |
O08565,P25930,P56498,P61073,P70658,P79394
Additional SwissProt Accessions: P70658,P25930,P56498,O08565,P79394,P61073 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Calcium signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Axon guidance, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer |
| Gene Ensembl | ENSECAG00000003837, ENSCAFG00845010172,ENSCAFG00845025560, ENSMUSG00000045382, ENSMMUG00000011918, ENSG00000121966 |
| Target Classification | GPCR, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.