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Human RUNX1/AML1/AML1-EVI-1 ORF/cDNA clone-Lentivirus particle (NM_001754.4)
Cat. No.: vGMLV000314
Pre-made Human RUNX1/AML1/AML1-EVI-1 Lentiviral expression plasmid for RUNX1 lentivirus packaging, RUNX1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLV000314 | Human RUNX1 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLV000314 |
| Gene Name | RUNX1 |
| Accession Number | NM_001754.4 |
| Gene ID | 861 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 1443 bp |
| Gene Alias | AML1,AML1-EVI-1,AMLCR1,CBF2alpha,CBFA2,EVI-1,PEBP2aB,PEBP2alpha |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | AM (C-Terminal） |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGCTTCAGACAGCATATTTGAGTCATTTCCTTCGTACCCACAGTGCTTCATGAGAGAATGCATACTTGGAATGAATCCTTCTAGAGACGTCCACGATGCCAGCACGAGCCGCCGCTTCACGCCGCCTTCCACCGCGCTGAGCCCAGGCAAGATGAGCGAGGCGTTGCCGCTGGGCGCCCCGGACGCCGGCGCTGCCCTGGCCGGCAAGCTGAGGAGCGGCGACCGCAGCATGGTGGAGGTGCTGGCCGACCACCCGGGCGAGCTGGTGCGCACCGACAGCCCCAACTTCCTCTGCTCCGTGCTGCCTACGCACTGGCGCTGCAACAAGACCCTGCCCATCGCTTTCAAGGTGGTGGCCCTAGGGGATGTTCCAGATGGCACTCTGGTCACTGTGATGGCTGGCAATGATGAAAACTACTCGGCTGAGCTGAGAAATGCTACCGCAGCCATGAAGAACCAGGTTGCAAGATTTAATGACCTCAGGTTTGTCGGTCGAAGTGGAAGAGGGAAAAGCTTCACTCTGACCATCACTGTCTTCACAAACCCACCGCAAGTCGCCACCTACCACAGAGCCATCAAAATCACAGTGGATGGGCCCCGAGAACCTCGAAGACATCGGCAGAAACTAGATGATCAGACCAAGCCCGGGAGCTTGTCCTTTTCCGAGCGGCTCAGTGAACTGGAGCAGCTGCGGCGCACAGCCATGAGGGTCAGCCCACACCACCCAGCCCCCACGCCCAACCCTCGTGCCTCCCTGAACCACTCCACTGCCTTTAACCCTCAGCCTCAGAGTCAGATGCAGGATACAAGGCAGATCCAACCATCCCCACCGTGGTCCTACGATCAGTCCTACCAATACCTGGGATCCATTGCCTCTCCTTCTGTGCACCCAGCAACGCCCATTTCACCTGGACGTGCCAGCGGCATGACAACCCTCTCTGCAGAACTTTCCAGTCGACTCTCAACGGCACCCGACCTGACAGCGTTCAGCGACCCGCGCCAGTTCCCCGCGCTGCCCTCCATCTCCGACCCCCGCATGCACTATCCAGGCGCCTTCACCTACTCCCCGACGCCGGTCACCTCGGGCATCGGCATCGGCATGTCGGCCATGGGCTCGGCCACGCGCTACCACACCTACCTGCCGCCGCCCTACCCCGGCTCGTCGCAAGCGCAGGGAGGCCCGTTCCAAGCCAGCTCGCCCTCCTACCACCTGTACTACGGCGCCTCGGCCGGCTCCTACCAGTTCTCCATGGTGGGCGGCGAGCGCTCGCCGCCGCGCATCCTGCCGCCCTGCACCAACGCCTCCACCGGCTCCGCGCTGCTCAACCCCAGCCTCCCGAACCAGAGCGACGTGGTGGAGGCCGAGGGCAGCCACAGCAACTCCCCCACCAACATGGCGCCCTCCGCGCGCCTGGAGGAGGCCGTGTGGAGGCCCTACTGA |
| ORF Protein Sequence | MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T43711-Ab | Anti-RUNX1 monoclonal antibody |
| Target Antigen | GM-Tg-g-T43711-Ag | RUNX1 protein |
| ORF Viral Vector | pGMLV000314 | Human RUNX1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000843 | Human RUNX1 Lentivirus plasmid |
| ORF Viral Vector | pGMPC001443 | Human RUNX1 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC001636 | Human RUNX1 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLV000314 | Human RUNX1 Lentivirus particle |
| ORF Viral Vector | vGMLV000843 | Human RUNX1 Lentivirus particle |
Target information
| Target ID | GM-T43711 |
| Target Name | RUNX1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
861 |
| Gene ID |
100051950 (Equus caballus), 101084898 (Felis catus), 12394 (Mus musculus), 487746 (Canis lupus familiaris) 50662 (Rattus norvegicus), 529631 (Bos taurus), 696749 (Macaca mulatta), 861 (Homo sapiens) |
| Gene Symbols & Synonyms | RUNX1,Runx1,AML1,Cbfa2,Pebp2a2,Pebpa2b,CBF-alpha-2,Aml1,PEA2-alpha,PEBP2-alpha,CBFA2,EVI-1,AMLCR1,PEBP2aB,CBF2alpha,AML1-EVI-1,PEBP2alpha |
| Target Alternative Names | AML1,AML1-EVI-1,AMLCR1,Acute myeloid leukemia 1 protein,Aml1,CBF-alpha-2,CBF2alpha,CBFA2,Cbfa2,Core-binding factor subunit alpha-2 (CBF-alpha-2),EVI-1,Oncogene AML-1,PEA2-alpha,PEBP2-alpha,PEBP2-alpha B),PEBP2aB,PEBP2alpha,Pebp2a2,Pebpa2b,Polyomavirus enhancer-binding protein 2 alpha B subunit (PEA2-alpha B,RUNX1,Runt-related transcription factor 1,Runx1,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core-binding factor alpha B subunit |
| Uniprot Accession |
Q01196,Q03347,Q63046
Additional SwissProt Accessions: Q03347,Q63046,Q01196 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | cancer |
| Disease from KEGG | Tight junction, Th17 cell differentiation, Pathways in cancer, Chronic myeloid leukemia, Acute myeloid leukemia |
| Gene Ensembl | ENSECAG00000003462, ENSMUSG00000022952, ENSCAFG00845026139, ENSBTAG00000004742, ENSMMUG00000001649, ENSG00000159216 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.