Human KRAS/C-K-RAS/c-Ki-ras2 ORF/cDNA clone-Lentivirus particle (NM_004985.4)
Cat. No.: vGMLP005746
Pre-made Human KRAS/C-K-RAS/c-Ki-ras2 Lentiviral expression plasmid for KRAS lentivirus packaging, KRAS lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP005746 | Human KRAS Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP005746 |
Gene Name | KRAS |
Accession Number | NM_004985.4 |
Gene ID | 3845 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 567 bp |
Gene Alias | C-K-RAS,c-Ki-ras2,CFC2,K-Ras,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS,NS3,RALD,RASK2 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGATTCCTACAGGAAGCAAGTAGTAATTGATGGAGAAACCTGTCTCTTGGATATTCTCGACACAGCAGGTCAAGAGGAGTACAGTGCAATGAGGGACCAGTACATGAGGACTGGGGAGGGCTTTCTTTGTGTATTTGCCATAAATAATACTAAATCATTTGAAGATATTCACCATTATAGAGAACAAATTAAAAGAGTTAAGGACTCTGAAGATGTACCTATGGTCCTAGTAGGAAATAAATGTGATTTGCCTTCTAGAACAGTAGACACAAAACAGGCTCAGGACTTAGCAAGAAGTTATGGAATTCCTTTTATTGAAACATCAGCAAAGACAAGACAGGGTGTTGATGATGCCTTCTATACATTAGTTCGAGAAATTCGAAAACATAAAGAAAAGATGAGCAAAGATGGTAAAAAGAAGAAAAAGAAGTCAAAGACAAAGTGTGTAATTATGTAA |
ORF Protein Sequence | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T59480-Ab | Anti-KRAS G12C monoclonal antibody |
Target Antigen | GM-Tg-g-T59480-Ag | KRAS G12C/KRAS protein |
ORF Viral Vector | pGMLP001359 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP001960 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005588 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005740 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005741 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005742 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005743 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005744 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005745 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005746 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005747 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005748 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005749 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005750 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005751 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005752 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005753 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005754 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005755 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005756 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005757 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005758 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005759 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005760 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005761 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005762 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005763 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005764 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005765 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005766 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005767 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005768 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005769 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005770 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005771 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005772 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005773 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005774 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005775 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005776 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005777 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005778 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005779 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005780 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005781 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005782 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP005807 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMLP-SPh-051 | Human KRAS Lentivirus plasmid |
ORF Viral Vector | pGMAP-SPh-191 | Human KRAS Adenovirus plasmid |
ORF Viral Vector | pGMPC000180 | Human Kras Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC000746 | Human KRAS Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP001359 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP001960 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005588 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005740 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005741 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005742 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005743 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005744 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005745 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005746 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005747 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005748 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005749 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005750 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005751 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005752 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005753 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005754 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005755 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005756 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005757 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005758 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005759 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005760 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005761 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005762 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005763 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005764 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005765 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005766 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005767 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005768 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005769 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005770 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005771 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005772 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005773 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005774 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005775 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005776 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005777 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005778 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005779 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005780 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005781 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005782 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP005807 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMLP-SPh-051 | Human KRAS Lentivirus particle |
ORF Viral Vector | vGMAP-SPh-191 | Human KRAS Adenovirus particle |
Target information
Target ID | GM-T59480 |
Target Name | KRAS G12C |
Gene Group Identifier (Target Gene ID in Homo species) |
3845 |
Gene ID |
100064473 (Equus caballus), 16653 (Mus musculus), 24525 (Rattus norvegicus), 3845 (Homo sapiens) 403871 (Canis lupus familiaris), 541140 (Bos taurus), 707977 (Macaca mulatta), 751104 (Felis catus) |
Gene Symbols & Synonyms | KRAS,Kras,ras,p21B,K-Ras,K-ras,Kras2,Ki-ras,Kras-2,K-Ras 2,c-K-ras,c-Ki-ras,p21,NS,NS3,OES,CFC2,RALD,KRAS1,KRAS2,RASK2,KI-RAS,C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,'C-K-RAS,c-Ki-ras2,K-RAS,p21ras |
Target Alternative Names | KRAS G12C,GTPase KRas,K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras,NS,NS3,OES,CFC2,RALD,K-Ras,KRAS1,KRAS2,RASK2,KI-RAS,C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,K-Ras 2,'C-K-RAS,c-Ki-ras,c-Ki-ras2 |
Uniprot Accession |
P01116,P08644,P32883
Additional SwissProt Accessions: P32883,P08644,P01116 |
Uniprot Entry Name | |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | cancer, Non-Small Cell Lung Cancer, Colorectal Cancer, Pancreas Cancer |
Disease from KEGG | EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, Gap junction, Signaling pathways regulating pluripotency of stem cells, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Regulation of actin cytoskeleton, GnRH signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis |
Gene Ensembl | ENSECAG00000019522, ENSMUSG00000030265, ENSG00000133703, ENSCAFG00845026771, ENSBTAG00000009778, ENSMMUG00000015381 |
Target Classification | Pathway, Checkpoint-Immuno Oncology |
About GMVC
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