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Human ICOSLG/B7-H2/B7H2 ORF/cDNA clone-Lentivirus particle (NM_015259)
Cat. No.: vGMLP002122
Pre-made Human ICOSLG/B7-H2/B7H2 Lentiviral expression plasmid for ICOSLG lentivirus packaging, ICOSLG lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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ICOSLG/B7-H2/CD275/B7RP1/ICOSLG/B7-H2 products
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLP002122 | Human ICOSLG Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLP002122 |
| Gene Name | ICOSLG |
| Accession Number | NM_015259 |
| Gene ID | 23308 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 909 bp |
| Gene Alias | B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGCGGCTGGGCAGTCCTGGACTGCTCTTCCTGCTCTTCAGCAGCCTTCGAGCTGATACTCAGGAGAAGGAAGTCAGAGCGATGGTAGGCAGCGACGTGGAGCTCAGCTGCGCTTGCCCTGAAGGAAGCCGTTTTGATTTAAATGATGTTTACGTATATTGGCAAACCAGTGAGTCGAAAACCGTGGTGACCTACCACATCCCACAGAACAGCTCCTTGGAAAACGTGGACAGCCGCTACCGGAACCGAGCCCTGATGTCACCGGCCGGCATGCTGCGGGGCGACTTCTCCCTGCGCTTGTTCAACGTCACCCCCCAGGACGAGCAGAAGTTTCACTGCCTGGTGTTGAGCCAATCCCTGGGATTCCAGGAGGTTTTGAGCGTTGAGGTTACACTGCATGTGGCAGCAAACTTCAGCGTGCCCGTCGTCAGCGCCCCCCACAGCCCCTCCCAGGATGAGCTCACCTTCACGTGTACATCCATAAACGGCTACCCCAGGCCCAACGTGTACTGGATCAATAAGACGGACAACAGCCTGCTGGACCAGGCTCTGCAGAATGACACCGTCTTCTTGAACATGCGGGGCTTGTATGACGTGGTCAGCGTGCTGAGGATCGCACGGACCCCCAGCGTGAACATTGGCTGCTGCATAGAGAACGTGCTTCTGCAGCAGAACCTGACTGTCGGCAGCCAGACAGGAAATGACATCGGAGAGAGAGACAAGATCACAGAGAATCCAGTCAGTACCGGCGAGAAAAACGCGGCCACGTGGAGCATCCTGGCTGTCCTGTGCCTGCTTGTGGTCGTGGCGGTGGCCATAGGCTGGGTGTGCAGGGACCGATGCCTCCAACACAGCTATGCAGGTGCCTGGGCTGTGAGTCCGGAGACAGAGCTCACTGGCCACGTTTGA |
| ORF Protein Sequence | MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTGHV |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-456 | Pre-Made Prezalumab biosimilar, Whole mAb, Anti-ICOSLG/B7RP1 Antibody: Anti-B7-H2/B7H2/B7h/CD275/GL50/ICOS-L/ICOSL/LICOS therapeutic antibody |
| Target Antibody | GM-Tg-g-T16144-Ab | Anti-ICOSL/ B7RP1/ ICOSLG monoclonal antibody |
| Target Antigen | GM-Tg-g-T16144-Ag | B7RP1/ICOSLG VLP (virus-like particle) |
| ORF Viral Vector | pGMLP002122 | Human ICOSLG Lentivirus plasmid |
| ORF Viral Vector | vGMLP002122 | Human ICOSLG Lentivirus particle |
Target information
| Target ID | GM-T16144 |
| Target Name | ICOSLG/B7-H2/CD275/B7RP1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
23308 |
| Gene ID |
100057048 (Equus caballus), 101091550 (Felis catus), 23308 (Homo sapiens), 487793 (Canis lupus familiaris) 499415 (Rattus norvegicus), 50723 (Mus musculus), 507857 (Bos taurus), 722191 (Macaca mulatta) |
| Gene Symbols & Synonyms | ICOSLG,Icoslg,Icosl,B7h,B7H2,GL50,B7-H2,B7RP1,CD275,ICOSL,LICOS,B7RP-1,ICOS-L,IMD119,RGD1562791,GI50,GL50-B,Ly115l,mKIAA0653 |
| Target Alternative Names | B7 homolog 2 (B7-H2),B7-H2,B7-like protein Gl50,B7-related protein 1 (B7RP-1),B7H2,B7RP-1,B7RP1,B7h,CD275,GI50,GL50,GL50-B,ICOS ligand,ICOS-L,ICOSL,ICOSLG,IMD119,Icosl,Icoslg,LICOS,Ly115l,RGD1562791,mKIAA0653 |
| Uniprot Accession |
O75144,Q9JHJ8
Additional SwissProt Accessions: O75144,Q9JHJ8 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | |
| Disease from KEGG | Cell adhesion molecules, Intestinal immune network for IgA production |
| Gene Ensembl | ENSECAG00000051827, ENSG00000160223, ENSCAFG00845019541, ENSMUSG00000000732, ENSBTAG00000014880, ENSMMUG00000010647 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.