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Human SMAD2/hMAD-2/hSMAD2 ORF/cDNA clone-Lentivirus particle (NM_005901.5)
Cat. No.: vGMLP-SPh-044
Pre-made Human SMAD2/hMAD-2/hSMAD2 Lentiviral expression plasmid for SMAD2 lentivirus packaging, SMAD2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLP-SPh-044 | Human SMAD2 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLP-SPh-044 |
| Gene Name | SMAD2 |
| Accession Number | NM_005901.5 |
| Gene ID | 4087 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 1404 bp |
| Gene Alias | hMAD-2,hSMAD2,JV18,JV18-1,MADH2,MADR2 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGATCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGAAACGCCACCTCCTGGATATATCAGTGAAGATGGAGAAACAAGTGACCAACAGTTGAATCAAAGTATGGACACAGGCTCTCCAGCAGAACTATCTCCTACTACTCTTTCCCCTGTTAATCATAGCTTGGATTTACAGCCAGTTACTTACTCAGAACCTGCATTTTGGTGTTCGATAGCATATTATGAATTAAATCAGAGGGTTGGAGAAACCTTCCATGCATCACAGCCCTCACTCACTGTAGATGGCTTTACAGACCCATCAAATTCAGAGAGGTTCTGCTTAGGTTTACTCTCCAATGTTAACCGAAATGCCACGGTAGAAATGACAAGAAGGCATATAGGAAGAGGAGTGCGCTTATACTACATAGGTGGGGAAGTTTTTGCTGAGTGCCTAAGTGATAGTGCAATCTTTGTGCAGAGCCCCAATTGTAATCAGAGATATGGCTGGCACCCTGCAACAGTGTGTAAAATTCCACCAGGCTGTAATCTGAAGATCTTCAACAACCAGGAATTTGCTGCTCTTCTGGCTCAGTCTGTTAATCAGGGTTTTGAAGCCGTCTATCAGCTAACTAGAATGTGCACCATAAGAATGAGTTTTGTGAAAGGGTGGGGAGCAGAATACCGAAGGCAGACGGTAACAAGTACTCCTTGCTGGATTGAACTTCATCTGAATGGACCTCTACAGTGGTTGGACAAAGTATTAACTCAGATGGGATCCCCTTCAGTGCGTTGCTCAAGCATGTCATAA |
| ORF Protein Sequence | MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-IP1753-Ab | Anti-SMAD2 monoclonal antibody |
| Target Antigen | GM-Tg-g-IP1753-Ag | SMAD2 protein |
| Cytokine | cks-Tg-g-GM-IP1753 | SMAD family member 2 (SMAD2) protein & antibody |
| ORF Viral Vector | pGMLP001353 | Human SMAD2 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000190 | Human SMAD2 Adenovirus plasmid |
| ORF Viral Vector | pGMLP-SPh-044 | Human SMAD2 Lentivirus plasmid |
| ORF Viral Vector | pGMAP-SPh-184 | Human SMAD2 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001202 | Human SMAD2 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC001609 | Human SMAD2 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLP001353 | Human SMAD2 Lentivirus particle |
| ORF Viral Vector | vGMAD000190 | Human SMAD2 Adenovirus particle |
| ORF Viral Vector | vGMLP-SPh-044 | Human SMAD2 Lentivirus particle |
| ORF Viral Vector | vGMAP-SPh-184 | Human SMAD2 Adenovirus particle |
Target information
| Target ID | GM-IP1753 |
| Target Name | SMAD2 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
4087 |
| Gene ID |
100033843 (Equus caballus), 101087179 (Felis catus), 17126 (Mus musculus), 29357 (Rattus norvegicus) 4087 (Homo sapiens), 480144 (Canis lupus familiaris), 516010 (Bos taurus), 697581 (Macaca mulatta) |
| Gene Symbols & Synonyms | SMAD2,Smad2,Madh2,Madr2,mMad2,Smad-2,7120426M23Rik,JV18,LDS6,CHTD8,MADH2,MADR2,JV18-1,hMAD-2,hSMAD2 |
| Target Alternative Names | 7120426M23Rik,CHTD8,JV18,JV18-1,LDS6,MAD homolog 2,MADH2,MADR2,Mad-related protein 2 (hMAD-2),Madh2,Madr2,Mothers against DPP homolog 2,Mothers against decapentaplegic homolog 2,SMAD family member 2 (SMAD 2,SMAD2,Smad-2,Smad2,hMAD-2,hSMAD2,hSMAD2),mMad2 |
| Uniprot Accession |
O70436,Q15796,Q1W668,Q62432
Additional SwissProt Accessions: Q62432,O70436,Q15796,Q1W668 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Cellular senescence, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th17 cell differentiation, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Chagas disease, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Pancreatic cancer, Hepatocellular carcinoma, Gastric cancer, Inflammatory bowel disease |
| Gene Ensembl | ENSECAG00000015132, ENSMUSG00000024563, ENSG00000175387, ENSCAFG00845002338, ENSBTAG00000039916, ENSMMUG00000007816 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.