Human PTEN/10q23del/BZS ORF/cDNA clone-Lentivirus particle (NM_000314)

Cat. No.: vGMLP-SPh-003

Pre-made Human PTEN/10q23del/BZS Lentiviral expression plasmid for PTEN lentivirus packaging, PTEN lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP-SPh-003 Human PTEN Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP-SPh-003
Gene Name PTEN
Accession Number NM_000314
Gene ID 5728
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 1212 bp
Gene Alias 10q23del,BZS,CWS1,DEC,GLM2,MHAM,MMAC1,PTEN1,PTENbeta,TEP1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACAGCCATCATCAAAGAGATCGTTAGCAGAAACAAAAGGAGATATCAAGAGGATGGATTCGACTTAGACTTGACCTATATTTATCCAAACATTATTGCTATGGGATTTCCTGCAGAAAGACTTGAAGGCGTATACAGGAACAATATTGATGATGTAGTAAGGTTTTTGGATTCAAAGCATAAAAACCATTACAAGATATACAATCTTTGTGCTGAAAGACATTATGACACCGCCAAATTTAATTGCAGAGTTGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGGAGTAACTATTCCCAGTCAGAGGCGCTATGTGTATTATTATAGCTACCTGTTAAAGAATCATCTGGATTATAGACCAGTGGCACTGTTGTTTCACAAGATGATGTTTGAAACTATTCCAATGTTCAGTGGCGGAACTTGCAATCCTCAGTTTGTGGTCTGCCAGCTAAAGGTGAAGATATATTCCTCCAATTCAGGACCCACACGACGGGAAGACAAGTTCATGTACTTTGAGTTCCCTCAGCCGTTACCTGTGTGTGGTGATATCAAAGTAGAGTTCTTCCACAAACAGAACAAGATGCTAAAAAAGGACAAAATGTTTCACTTTTGGGTAAATACATTCTTCATACCAGGACCAGAGGAAACCTCAGAAAAAGTAGAAAATGGAAGTCTATGTGATCAAGAAATCGATAGCATTTGCAGTATAGAGCGTGCAGATAATGACAAGGAATATCTAGTACTTACTTTAACAAAAAATGATCTTGACAAAGCAAATAAAGACAAAGCCAACCGATACTTTTCTCCAAATTTTAAGGTGAAGCTGTACTTCACAAAAACAGTAGAGGAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACCACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGA
ORF Protein Sequence MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T38257-Ab Anti-PTEN/ 10q23del/ BZS monoclonal antibody
    Target Antigen GM-Tg-g-T38257-Ag PTEN VLP (virus-like particle)
    ORF Viral Vector pGMLP005649 Human PTEN Lentivirus plasmid
    ORF Viral Vector pGMLV000452 Human PTEN Lentivirus plasmid
    ORF Viral Vector pGMLV001225 Human PTEN Lentivirus plasmid
    ORF Viral Vector pGMLV002290 Human PTEN Lentivirus plasmid
    ORF Viral Vector pGMAD000006 Human PTEN Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-003 Human PTEN Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-143 Human PTEN Adenovirus plasmid
    ORF Viral Vector pGMPC000358 Human PTEN Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001526 Human PTEN Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001692 Human PTEN Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004795 Human PTEN Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005649 Human PTEN Lentivirus particle
    ORF Viral Vector vGMLV000452 Human PTEN Lentivirus particle
    ORF Viral Vector vGMLV001225 Human PTEN Lentivirus particle
    ORF Viral Vector vGMLV002290 Human PTEN Lentivirus particle
    ORF Viral Vector vGMAD000006 Human PTEN Adenovirus particle
    ORF Viral Vector vGMLP-SPh-003 Human PTEN Lentivirus particle
    ORF Viral Vector vGMAP-SPh-143 Human PTEN Adenovirus particle


    Target information

    Target ID GM-T38257
    Target Name PTEN
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5728
    Gene ID 100062388 (Equus caballus), 101091813 (Felis catus), 19211 (Mus musculus), 403832 (Canis lupus familiaris)
    50557 (Rattus norvegicus), 540786 (Bos taurus), 5728 (Homo sapiens), 705121 (Macaca mulatta)
    Gene Symbols & Synonyms PTEN,Pten,TEP1,MMAC1,PTENbeta,2310035O07Rik,A130070J02Rik,B430203M17Rik,Mmac,BZS,DEC,CWS1,GLM2,MHAM,PTEN1,10q23del,PTENgama
    Target Alternative Names 10q23del,2310035O07Rik,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN,A130070J02Rik,B430203M17Rik,BZS,CWS1,DEC,GLM2,Inositol polyphosphate 3-phosphatase,MHAM,MMAC1,Mmac,Mutated in multiple advanced cancers 1,PTEN,PTEN1,PTENbeta,PTENgama,Phosphatase and tensin homolog,Phosphatidylinositol 3,Pten,TEP1
    Uniprot Accession O08586,O54857,P60483,P60484
    Additional SwissProt Accessions: O08586,P60483,O54857,P60484
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Metabolic pathways, EGFR tyrosine kinase inhibitor resistance, FoxO signaling pathway, Sphingolipid signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Focal adhesion, Insulin resistance, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Pathways in cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Central carbon metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
    Gene Ensembl ENSECAG00000017012, ENSMUSG00000013663, ENSCAFG00845029443, ENSBTAG00000009498, ENSG00000171862, ENSMMUG00000008431
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

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