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Human IL5/EDF/IL-5 ORF/cDNA clone-Lentivirus particle (NM_000879)
Cat. No.: vGMLP-IL-008
Pre-made Human IL5/EDF/IL-5 Lentiviral expression plasmid for IL5 lentivirus packaging, IL5 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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MSDS
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLP-IL-008 | Human IL5 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLP-IL-008 |
| Gene Name | IL5 |
| Accession Number | NM_000879 |
| Gene ID | 3567 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 405 bp |
| Gene Alias | EDF,IL-5,TRF |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAGGATGCTTCTGCATTTGAGTTTGCTAGCTCTTGGAGCTGCCTACGTGTATGCCATCCCCACAGAAATTCCCACAAGTGCATTGGTGAAAGAGACCTTGGCACTGCTTTCTACTCATCGAACTCTGCTGATAGCCAATGAGACTCTGAGGATTCCTGTTCCTGTACATAAAAATCACCAACTGTGCACTGAAGAAATCTTTCAGGGAATAGGCACACTGGAGAGTCAAACTGTGCAAGGGGGTACTGTGGAAAGACTATTCAAAAACTTGTCCTTAATAAAGAAATACATTGACGGCCAAAAAAAAAAGTGTGGAGAAGAAAGACGGAGAGTAAACCAATTCCTAGACTACCTGCAAGAGTTTCTTGGTGTAATGAACACCGAGTGGATAATAGAAAGTTGA |
| ORF Protein Sequence | MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-479 | Pre-Made Reslizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Biosimilar | GMP-Bios-ab-142 | Pre-Made Depemokimab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Biosimilar | GMP-Bios-ab-341 | Pre-Made Mepolizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Target Antibody | GM-Tg-g-T78585-Ab | Anti-IL5/ EDF/ IL-5 functional antibody |
| Target Antigen | GM-Tg-g-T78585-Ag | IL5 protein |
| ORF Viral Vector | pGMLP004769 | Human IL5 Lentivirus plasmid |
| ORF Viral Vector | pGMLP-IL-008 | Human IL5 Lentivirus plasmid |
| ORF Viral Vector | pGMAP-IL-091 | Human IL5 Adenovirus plasmid |
| ORF Viral Vector | vGMLP004769 | Human IL5 Lentivirus particle |
| ORF Viral Vector | vGMLP-IL-008 | Human IL5 Lentivirus particle |
| ORF Viral Vector | vGMAP-IL-091 | Human IL5 Adenovirus particle |
Target information
| Target ID | GM-T78585 |
| Target Name | IL-5/IL5 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
3567 |
| Gene ID |
100034199 (Equus caballus), 16191 (Mus musculus), 24497 (Rattus norvegicus), 280825 (Bos taurus) 3567 (Homo sapiens), 403790 (Canis lupus familiaris), 493803 (Felis catus), 710622 (Macaca mulatta) |
| Gene Symbols & Synonyms | IL5,Il5,IL-5,Il-5,TRF,EDF |
| Target Alternative Names | B-cell differentiation factor I,EDF,Eosinophil differentiation factor,IL-5,IL5,Il-5,Il5,Interleukin-5,T-cell replacing factor (TRF),TRF |
| Uniprot Accession |
O02699,O77515,P04401,P05113,P48093,P52173,Q08125,Q95J76
Additional SwissProt Accessions: O02699,P04401,Q08125,P52173,P05113,Q95J76,O77515,P48093 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index |
| Disease | Hodgkin's disease, Overactive bladder |
| Disease from KEGG | Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Intestinal immune network for IgA production, Pathways in cancer, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Allograft rejection |
| Gene Ensembl | ENSECAG00000016648, ENSMUSG00000036117, ENSBTAG00000031235, ENSG00000113525, ENSCAFG00845010566, ENSMMUG00000051989 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.