Human BIRC5/EPR-1 ORF/cDNA clone-Adenovirus particle (BC008718)
Cat. No.: vGMAP000202
Pre-made Human BIRC5/EPR-1 Adenovirus for BIRC5 overexpression in-vitro and in-vivo. The BIRC5 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified BIRC5-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000202 | Human BIRC5 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000202 |
| Gene Name | BIRC5 |
| Accession Number | BC008718 |
| Gene ID | 332 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 429 bp |
| Gene Alias | EPR-1 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Kanamycin |
| ORF Nucleotide Sequence | ATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAGCAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGAAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGA |
| ORF Protein Sequence | MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T02677-Ab | Anti-BIRC5 monoclonal antibody |
| Target Antigen | GM-Tg-g-T02677-Ag | BIRC5 protein |
| ORF Viral Vector | pGMAP000202 | Human BIRC5 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001492 | Human BIRC5 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC001525 | Human BIRC5 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMAP000202 | Human BIRC5 Adenovirus particle |
Target information
| Target ID | GM-T02677 |
| Target Name | SURVIVIN/BIRC5 |
|
Gene Group Identifier (Target Gene ID in Homo species) |
332 |
| Gene ID |
100050808 (Equus caballus), 11799 (Mus musculus), 332 (Homo sapiens), 414925 (Bos taurus) 442936 (Canis lupus familiaris), 493835 (Felis catus), 64041 (Rattus norvegicus), 709565 (Macaca mulatta) |
| Gene Symbols & Synonyms | BIRC5,Birc5,Api4,TIAP,AAC-11,survivin40,API4,EPR-1,AP14 |
| Target Alternative Names | AAC-11,AP14,API4,Api4,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,BIRC5,Baculoviral IAP repeat-containing protein 5,Birc5,EPR-1,SURVIVIN,TIAP,survivin40 |
| Uniprot Accession |
O15392,O70201,Q6I6F4,Q6J1J1,Q8I009,Q9JHY7
Additional SwissProt Accessions: O70201,O15392,Q6J1J1,Q8I009,Q6I6F4,Q9JHY7 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | cancer, Breast Cancer, Malignant neoplasm of bladder |
| Disease from KEGG | Apoptosis, Apoptosis - multiple species, Hippo signaling pathway, Hepatitis B, Pathways in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer |
| Gene Ensembl | ENSMUSG00000017716, ENSG00000089685, ENSBTAG00000013573, ENSMMUG00000013767 |
| Target Classification | Checkpoint-Immuno Oncology |
About GMVC

GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.


