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Human TTR/HsT2651/TBPA ORF/cDNA clone-Adenovirus particle (BC005310)
Cat. No.: vGMAP000187
Pre-made Human TTR/HsT2651/TBPA Adenovirus for TTR overexpression in-vitro and in-vivo. The TTR adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified TTR-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Prealbumin/transthyretin/TTR/TTR/HsT2651 products
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000187 | Human TTR Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000187 |
| Gene Name | TTR |
| Accession Number | BC005310 |
| Gene ID | 7276 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 444 bp |
| Gene Alias | HsT2651,TBPA |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Kanamycin |
| ORF Nucleotide Sequence | ATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTTGTGTCTGAGGCTGGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTTCTAGATGCTGTCCGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCTGCTGATGACACCTGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACTGAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAAGGCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACAGCCAACGACTCCGGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTATTCCACCACGGCTGTCGTCACCAATCCCAAGGAATGA |
| ORF Protein Sequence | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T86462-Ab | Anti-TTHY/ TTR/ ATTR functional antibody |
| Target Antigen | GM-Tg-g-T86462-Ag | TTR protein |
| ORF Viral Vector | pGMLP000332 | Human TTR Lentivirus plasmid |
| ORF Viral Vector | pGMLP002013 | Human TTR Lentivirus plasmid |
| ORF Viral Vector | pGMAP000187 | Human TTR Adenovirus plasmid |
| ORF Viral Vector | pGMPC001668 | Human TTR Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLP000332 | Human TTR Lentivirus particle |
| ORF Viral Vector | vGMLP002013 | Human TTR Lentivirus particle |
| ORF Viral Vector | vGMAP000187 | Human TTR Adenovirus particle |
Target information
| Target ID | GM-T86462 |
| Target Name | Prealbumin/transthyretin/TTR |
|
Gene Group Identifier （Target Gene ID in Homo species) |
7276 |
| Gene ID |
100052147 (Equus caballus), 101085927 (Felis catus), 22139 (Mus musculus), 24856 (Rattus norvegicus) 280948 (Bos taurus), 480167 (Canis lupus familiaris), 705943 (Macaca mulatta), 7276 (Homo sapiens) |
| Gene Symbols & Synonyms | TTR,Ttr,prealbumin,TT,Lr1,Tbpa,TTR1,CTS,TTN,ATTR,CTS1,PALB,TBPA,HEL111,HsT2651 |
| Target Alternative Names | ATTR,CTS,CTS1,HEL111,HsT2651,Lr1,PALB,Prealbumin,TBPA,TT,TTN,TTR,TTR1,Tbpa,Transthyretin,Ttr,prealbumin,transthyretin |
| Uniprot Accession |
O46375,P02766,P02767,P07309
Additional SwissProt Accessions: P07309,P02767,O46375,P02766 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | Ovary Cancer, hepatitis B, ovarian cancer, Diabetic Nephropathy, Alzheimer's Disease, Choroid plexus tumors, Dent disease, IgA glomerulonephritis, Nephrotic syndrome with focal and segmental glomerular lesions, Type 2 diabetes mellitus |
| Disease from KEGG | Thyroid hormone synthesis |
| Gene Ensembl | ENSECAG00000015875, ENSMUSG00000061808, ENSBTAG00000010991, ENSCAFG00845010593, ENSMMUG00000052277, ENSG00000118271 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.