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Human SERPINE1/PAI/PAI-1 ORF/cDNA clone-Adenovirus particle (BC010860)
Cat. No.: vGMAP000049
Pre-made Human SERPINE1/PAI/PAI-1 Adenovirus for SERPINE1 overexpression in-vitro and in-vivo. The SERPINE1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified SERPINE1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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PAI-1/Serpin E1/SERPINE1/SERPINE1/PAI products
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000049 | Human SERPINE1 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000049 |
| Gene Name | SERPINE1 |
| Accession Number | BC010860 |
| Gene ID | 5054 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 1209 bp |
| Gene Alias | PAI,PAI-1 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Kanamycin |
| ORF Nucleotide Sequence | ATGCAGATGTCTCCAGCCCTCACCTGCCTAGTCCTGGGCCTGGCCCTTGTCTTTGGTGAAGGGTCTGCTGTGCACCATCCCCCATCCTACGTGGCCCACCTGGCCTCAGACTTCGGGGTGAGGGTGTTTCAGCAGGTGGCGCAGGCCTCCAAGGACCGCAACGTGGTTTTCTCACCCTATGGGGTGGCCTCGGTGTTGGCCATGCTCCAGCTGACAACAGGAGGAGAAACCCAGCAGCAGATTCAAGCAGCTATGGGATTCAAGATTGATGACAAGGGCATGGCCCCCGCCCTCCGGCATCTGTACAAGGAGCTCATGGGGCCATGGAACAAGGATGAGATCAGCACCACAGACGCGATCTTCGTCCAGCGGGATCTGAAGCTGGTCCAGGGCTTCATGCCCCACTTCTTCAGGCTGTTCCGGAGCACGGTCAAGCAAGTGGACTTTTCAGAGGTGGAGAGAGCCAGATTCATCATCAATGACTGGGTGAAGACACACACAAAAGGTATGATCAGCAACTTGCTTGGGAAAGGAGCCGTGGACCAGCTGACACGGCTGGTGCTGGTGAATGCCCTCTACTTCAACGGCCAGTGGAAGACTCCCTTCCCCGACTCCAGCACCCACCGCCGCCTCTTCCACAAATCAGACGGCAGCACTGTCTCTGTGCCCATGATGGCTCAGACCAACAAGTTCAACTATACTGAGTTCACCACGCCCGATGGCCATTACTACGACATCCTGGAACTGCCCTACCACGGGGACACCCTCAGCATGTTCATTGCTGCCCCTTATGAAAAAGAGGTGCCTCTCTCTGCCCTCACCAACATTCTGAGTGCCCAGCTCATCAGCCACTGGAAAGGCAACATGACCAGGCTGCCCCGCCTCCTGGTTCTGCCCAAGTTCTCCCTGGAGACTGAAGTCGACCTCAGGAAGCCCCTAGAGAACCTGGGAATGACCGACATGTTCAGACAGTTTCAGGCTGACTTCACGAGTCTTTCAGACCAAGAGCCTCTCCACGTCGCGCAGGCGCTGCAGAAAGTGAAGATCGAGGTGAACGAGAGTGGCACGGTGGCCTCCTCATCCACAGCTGTCATAGTCTCAGCCCGCATGGCCCCCGAGGAGATCATCATGGACAGACCCTTCCTCTTTGTGGTCCGGCACAACCCCACAGGAACAGTCCTTTTCATGGGCCAAGTGATGGAACCCTGA |
| ORF Protein Sequence | MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T15556-Ab | Anti-PAI1/ SERPINE1/ PAI monoclonal antibody |
| Target Antigen | GM-Tg-g-T15556-Ag | SERPINE1 VLP (virus-like particle) |
| Cytokine | cks-Tg-g-GM-T15556 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1) protein & antibody |
| ORF Viral Vector | pGMLP000493 | Human SERPINE1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002209 | Human SERPINE1 Lentivirus plasmid |
| ORF Viral Vector | pGMAP000049 | Human SERPINE1 Adenovirus plasmid |
| ORF Viral Vector | vGMLP000493 | Human SERPINE1 Lentivirus particle |
| ORF Viral Vector | vGMLV002209 | Human SERPINE1 Lentivirus particle |
| ORF Viral Vector | vGMAP000049 | Human SERPINE1 Adenovirus particle |
Target information
| Target ID | GM-T15556 |
| Target Name | PAI-1/Serpin E1/SERPINE1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
5054 |
| Gene ID |
100033931 (Equus caballus), 100127105 (Felis catus), 18787 (Mus musculus), 24617 (Rattus norvegicus) 281375 (Bos taurus), 403476 (Canis lupus familiaris), 5054 (Homo sapiens), 713883 (Macaca mulatta) |
| Gene Symbols & Synonyms | SERPINE1,Serpine1,PAI-1,PAI1,Planh1,Pai1,PAI1A,Planh,Pai1aa,RATPAI1A,PAI,PLANH1 |
| Target Alternative Names | Endothelial plasminogen activator inhibitor,PAI,PAI-1,PAI1,PAI1A,PLANH1,Pai1,Pai1aa,Planh,Planh1,Plasminogen activator inhibitor 1,RATPAI1A,SERPINE1,Serpin E1,Serpine1 |
| Uniprot Accession |
P05121,P13909,P20961,P22777
Additional SwissProt Accessions: P22777,P20961,P13909,P05121 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | cancer, Ovary Cancer, Malignant neoplasm of bladder |
| Disease from KEGG | HIF-1 signaling pathway, p53 signaling pathway, Cellular senescence, Hippo signaling pathway, Complement and coagulation cascades, AGE-RAGE signaling pathway in diabetic complications, Chagas disease |
| Gene Ensembl | ENSECAG00000019781, ENSMUSG00000037411, ENSCAFG00845000607, ENSG00000106366, ENSMMUG00000009926 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.