Human SMAD1/BSP1/JV4-1 ORF/cDNA clone-Adenovirus particle (BC001878)

Cat. No.: vGMAP-SPh-183

Pre-made Human SMAD1/BSP1/JV4-1 Adenovirus for SMAD1 overexpression in-vitro and in-vivo. The SMAD1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified SMAD1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP-SPh-183 Human SMAD1 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP-SPh-183
Gene Name SMAD1
Accession Number BC001878
Gene ID 4086
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1398 bp
Gene Alias BSP1,JV4-1,JV41,MADR1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGAATGTGACAAGTTTATTTTCCTTTACAAGTCCAGCTGTGAAGAGACTTCTTGGGTGGAAACAGGGCGATGAAGAAGAAAAATGGGCAGAGAAAGCTGTTGATGCTTTGGTGAAAAAACTGAAGAAAAAGAAAGGTGCCATGGAGGAACTGGAAAAGGCCTTGAGCTGCCCAGGGCAACCGAGTAACTGTGTCACCATTCCCCGCTCTCTGGATGGCAGGCTGCAAGTCTCCCACCGGAAGGGACTGCCTCATGTCATTTACTGCCGTGTGTGGCGCTGGCCCGATCTTCAGAGCCACCATGAACTAAAACCACTGGAATGCTGTGAGTTTCCTTTTGGTTCCAAGCAGAAGGAGGTCTGCATCAATCCCTACCACTATAAGAGAGTAGAAAGCCCTGTACTTCCTCCTGTGCTGGTTCCAAGACACAGCGAATATAATCCTCAGCACAGCCTCTTAGCTCAGTTCCGTAACTTAGGACAAAATGAGCCTCACATGCCACTCAACGCCACTTTTCCAGATTCTTTCCAGCAACCCAACAGCCACCCGTTTCCTCACTCTCCCAATAGCAGTTACCCAAACTCTCCTGGGAGCAGCAGCAGCACCTACCCTCACTCTCCCACCAGCTCAGACCCAGGAAGCCCTTTCCAGATGCCAGCTGATACGCCCCCACCTGCTTACCTGCCTCCTGAAGACCCCATGACCCAGGATGGCTCTCAGCCGATGGACACAAACATGATGGCGCCTCCCCTGCCCTCAGAAATCAACAGAGGAGATGTTCAGGCGGTTGCTTATGAGGAACCAAAACACTGGTGCTCTATTGTCTACTATGAGCTCAACAATCGTGTGGGTGAAGCGTTCCATGCCTCCTCCACAAGTGTGTTGGTGGATGGTTTCACTGATCCTTCCAACAATAAGAACCGTTTCTGCCTTGGGCTGCTCTCCAATGTTAACCGGAATTCCACTATTGAAAACACCAGGCGGCATATTGGAAAAGGAGTTCATCTTTATTATGTTGGAGGGGAGGTGTATGCCGAATGCCTTAGTGACAGTAGCATCTTTGTGCAAAGTCGGAACTGCAACTACCATCATGGATTTCATCCTACTACTGTTTGCAAGATCCCTAGTGGGTGTAGTCTGAAAATTTTTAACAACCAAGAATTTGCTCAGTTATTGGCACAGTCTGTGAACCATGGATTTGAGACAGTCTATGAGCTTACAAAAATGTGTACTATACGTATGAGCTTTGTGAAGGGCTGGGGAGCAGAATACCACCGCCAGGATGTTACTAGCACCCCCTGCTGGATTGAGATACATCTGCACGGCCCCCTCCAGTGGCTGGATAAAGTTCTTACTCAAATGGGTTCACCTCATAATCCTATTTCATCTGTATCTTAA
ORF Protein Sequence MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP2743-Ab Anti-SMAD1 monoclonal antibody
    Target Antigen GM-Tg-g-IP2743-Ag SMAD1 protein
    Cytokine cks-Tg-g-GM-IP2743 SMAD family member 1 (SMAD1) protein & antibody
    ORF Viral Vector pGMLP000523 Human SMAD1 Lentivirus plasmid
    ORF Viral Vector pGMLV002299 Human SMAD1 Lentivirus plasmid
    ORF Viral Vector pGMAP000218 Human SMAD1 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-043 Human SMAD1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-183 Human SMAD1 Adenovirus plasmid
    ORF Viral Vector vGMLP000523 Human SMAD1 Lentivirus particle
    ORF Viral Vector vGMLV002299 Human SMAD1 Lentivirus particle
    ORF Viral Vector vGMAP000218 Human SMAD1 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-043 Human SMAD1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-183 Human SMAD1 Adenovirus particle


    Target information

    Target ID GM-IP2743
    Target Name SMAD1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		4086
    Gene ID 100033850 (Equus caballus), 101085713 (Felis catus), 17125 (Mus musculus), 25671 (Rattus norvegicus)
    4086 (Homo sapiens), 475456 (Canis lupus familiaris), 540488 (Bos taurus), 574340 (Macaca mulatta)
    Gene Symbols & Synonyms SMAD1,Smad1,Mad1,Mlp1,Madh1,Madr1,dwf-A,mMad1,MusMLP,BSP1,JV41,BSP-1,JV4-1,MADH1,MADR1
    Target Alternative Names BSP-1,BSP1,JV4-1,JV41,MAD homolog 1,MADH1,MADR1,Mad-related protein 1,Mad1,Madh1,Madr1,Mlp1,Mothers against DPP homolog 1,Mothers against decapentaplegic homolog 1,MusMLP,SMAD family member 1 (SMAD 1,SMAD1,Smad1,Transforming growth factor-beta-signaling protein 1 (BSP-1),dwf-A,hSMAD1),mMad1
    Uniprot Accession P70340,P97588,Q15797,Q1JQA2
    Additional SwissProt Accessions: P70340,P97588,Q15797,Q1JQA2
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Cytokine Target
    Disease cancer
    Disease from KEGG TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells
    Gene Ensembl ENSECAG00000022649, ENSMUSG00000031681, ENSG00000170365, ENSCAFG00845012104, ENSBTAG00000002835, ENSMMUG00000018384
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.