Human RUNX2/AML3/CBF-alpha-1 ORF/cDNA clone-Adenovirus particle (NM_001024630.4)

Cat. No.: vGMAD000989

Pre-made Human RUNX2/AML3/CBF-alpha-1 Adenovirus for RUNX2 overexpression in-vitro and in-vivo. The RUNX2 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified RUNX2-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000989 Human RUNX2 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000989
Gene Name RUNX2
Accession Number NM_001024630.4
Gene ID 860
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1566 bp
Gene Alias AML3,CBF-alpha-1,CBFA1,CCD,CCD1,CLCD,OSF-2,OSF2,PEA2aA,PEBP2aA
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGGCATCAAACAGCCTCTTCAGCACAGTGACACCATGTCAGCAAAACTTCTTTTGGGATCCGAGCACCAGCCGGCGCTTCAGCCCCCCCTCCAGCAGCCTGCAGCCCGGCAAAATGAGCGACGTGAGCCCGGTGGTGGCTGCGCAACAGCAGCAGCAACAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGGAGGCGGCGGCGGCGGCTGCGGCGGCGGCGGCGGCTGCGGCGGCGGCAGCTGCAGTGCCCCGGTTGCGGCCGCCCCACGACAACCGCACCATGGTGGAGATCATCGCCGACCACCCGGCCGAACTCGTCCGCACCGACAGCCCCAACTTCCTGTGCTCGGTGCTGCCCTCGCACTGGCGCTGCAACAAGACCCTGCCCGTGGCCTTCAAGGTGGTAGCCCTCGGAGAGGTACCAGATGGGACTGTGGTTACTGTCATGGCGGGTAACGATGAAAATTATTCTGCTGAGCTCCGGAATGCCTCTGCTGTTATGAAAAACCAAGTAGCAAGGTTCAACGATCTGAGATTTGTGGGCCGGAGTGGACGAGGCAAGAGTTTCACCTTGACCATAACCGTCTTCACAAATCCTCCCCAAGTAGCTACCTATCACAGAGCAATTAAAGTTACAGTAGATGGACCTCGGGAACCCAGAAGGCACAGACAGAAGCTTGATGACTCTAAACCTAGTTTGTTCTCTGACCGCCTCAGTGATTTAGGGCGCATTCCTCATCCCAGTATGAGAGTAGGTGTCCCGCCTCAGAACCCACGGCCCTCCCTGAACTCTGCACCAAGTCCTTTTAATCCACAAGGACAGAGTCAGATTACAGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCCACCTCTGACTTCTGCCTCTGGCCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTTTGGCGACCATATTGA
ORF Protein Sequence MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T02259-Ab Anti-RUNX2 monoclonal antibody
    Target Antigen GM-Tg-g-T02259-Ag RUNX2 protein
    ORF Viral Vector pGMLP001724 Human RUNX2 Lentivirus plasmid
    ORF Viral Vector pGMAD000989 Human RUNX2 Adenovirus plasmid
    ORF Viral Vector pGMPC000085 Human RUNX2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000917 Human RUNX2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001724 Human RUNX2 Lentivirus particle
    ORF Viral Vector vGMAD000989 Human RUNX2 Adenovirus particle


    Target information

    Target ID GM-T02259
    Target Name RUNX2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		860
    Gene ID 100033890 (Equus caballus), 101089612 (Felis catus), 12393 (Mus musculus), 367218 (Rattus norvegicus)
    449531 (Canis lupus familiaris), 536911 (Bos taurus), 703331 (Macaca mulatta), 860 (Homo sapiens)
    Gene Symbols & Synonyms RUNX2,Runx2,Cbf,LS3,AML3,Osf2,Cbfa1,Cbfa-1,PEBP2aA,Pebp2a1,Pebpa2a,CBF-alpha-1,OSF-2,CCD,CCD1,CLCD,OSF2,CBFA1,PEA2aA
    Target Alternative Names AML3,Acute myeloid leukemia 3 protein,CBF-alpha-1,CBFA1,CCD,CCD1,CLCD,Cbf,Cbfa-1,Cbfa1,Core-binding factor subunit alpha-1 (CBF-alpha-1),LS3,OSF-2,OSF2,Oncogene AML-3,Osf2,Osteoblast-specific transcription factor 2 (OSF-2),PEA2aA,PEBP2-alpha A),PEBP2aA,Pebp2a1,Pebpa2a,Polyomavirus enhancer-binding protein 2 alpha A subunit (PEA2-alpha A,RUNX2,Runt-related transcription factor 2,Runx2,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit
    Uniprot Accession Q08775,Q13950,Q9XSB7,Q9Z2J9
    Additional SwissProt Accessions: Q9XSB7,Q08775,Q9Z2J9,Q13950
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Parathyroid hormone synthesis, secretion and action
    Gene Ensembl ENSECAG00000020875, ENSMUSG00000039153, ENSCAFG00845012369, ENSBTAG00000004104, ENSMMUG00000019819, ENSG00000124813
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.