Human DIO2/5DII/D2 ORF/cDNA clone-Adenovirus particle (NM_013989)

Cat. No.: vGMAD000267

Pre-made Human DIO2/5DII/D2 Adenovirus for DIO2 overexpression in-vitro and in-vivo. The DIO2 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified DIO2-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collection

Go to DIO2/5DII products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdf MSDS
pdf Datasheet

Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000267 Human DIO2 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000267
Gene Name DIO2
Accession Number NM_013989
Gene ID 1734
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 822 bp
Gene Alias 5DII,D2,DIOII,SelY,TXDI2
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGCATCCTCAGCGTAGACTTGCTGATCACACTGCAAATTCTGCCAGTTTTTTTCTCCAACTGCCTCTTCCTGGCTCTCTATGACTCGGTCATTCTGCTCAAGCACGTGGTGCTGCTGTTGAGCCGCTCCAAGTCCACTCGCGGAGAGTGGCGGCGCATGCTGACCTCAGAGGGACTGCGCTGCGTCTGGAAGAGCTTCCTCCTCGATGCCTACAAACAGGTGAAATTGGGTGAGGATGCCCCCAATTCCAGTGTGGTGCATGTCTCCAGTACAGAAGGAGGTGACAACAGTGGCAATGGTACCCAGGAGAAGATAGCTGAGGGAGCCACATGCCACCTTCTTGACTTTGCCAGCCCTGAGCGCCCACTAGTGGTCAACTTTGGCTCAGCCACTTGACCTCCTTTCACGAGCCAGCTGCCAGCCTTCCGCAAACTGGTGGAAGAGTTCTCCTCAGTGGCTGACTTCCTGCTGGTCTACATTGATGAGGCTCATCCATCAGATGGCTGGGCGATACCGGGGGACTCCTCTTTGTCTTTTGAGGTGAAGAAGCACCAGAACCAGGAAGATCGATGTGCAGCAGCCCAGCAGCTTCTGGAGCGTTTCTCCTTGCCGCCCCAGTGCCGAGTTGTGGCTGACCGCATGGACAATAACGCCAACATAGCTTACGGGGTAGCCTTTGAACGTGTGTGCATTGTGCAGAGACAGAAAATTGCTTATCTGGGAGGAAAGGGCCCCTTCTCCTACAACCTTCAAGAAGTCCGGCATTGGCTGGAGAAGAATTTCAGCAAGAGATGAAAGAAAACTAGATTAGCTGGTTAA
ORF Protein Sequence MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0359-Ab Anti-IOD2/ DIO2/ 5DII monoclonal antibody
    Target Antigen GM-Tg-g-MP0359-Ag DIO2 VLP (virus-like particle)
    ORF Viral Vector pGMAD000267 Human DIO2 Adenovirus plasmid
    ORF Viral Vector vGMAD000267 Human DIO2 Adenovirus particle


    Target information

    Target ID GM-MP0359
    Target Name DIO2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1734
    Gene ID 100052547 (Equus caballus), 101088170 (Felis catus), 13371 (Mus musculus), 1734 (Homo sapiens)
    490813 (Canis lupus familiaris), 494548 (Bos taurus), 65162 (Rattus norvegicus), 707484 (Macaca mulatta)
    Gene Symbols & Synonyms DIO2,Dio2,5DII,DIOII,D2,SelY,TXDI2,SELENOY
    Target Alternative Names 5DII,D2,DIO2,DIOII,Dio2,SELENOY,SelY,TXDI2,Type 2 DI,Type II iodothyronine deiodinase,Type-II 5'-deiodinase
    Uniprot Accession P70551,Q5I3B2,Q92813,Q9Z1Y9
    Additional SwissProt Accessions: Q9Z1Y9,Q92813,Q5I3B2,P70551
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category
    Disease
    Disease from KEGG Thyroid hormone signaling pathway
    Gene Ensembl ENSECAG00000030788, ENSMUSG00000007682, ENSG00000211448, ENSBTAG00000064181
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.