Human CYP19A1/ARO/ARO1 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_000103.4)

Cat. No.: vGMAAV001256

Pre-made Human CYP19A1/ARO/ARO1 Adeno-associated virus particle for CYP19A1 in-vivo study, mechanism of action (MOA) research and CYP19A1-associated gene therapy development.

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Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV001256 Human CYP19A1 Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV001256
Gene Name CYP19A1
Accession Number NM_000103.4
Gene ID 1588
Species Human
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 1512 bp
Gene Alias ARO,ARO1,CPV1,CYAR,CYP19,CYPXIX,P-450AROM
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter hSyn
Resistance Amplicin
ORF Nucleotide Sequence ATGGTTTTGGAAATGCTGAACCCGATACATTATAACATCACCAGCATCGTGCCTGAAGCCATGCCTGCTGCCACCATGCCAGTCCTGCTCCTCACTGGCCTTTTTCTCTTGGTGTGGAATTATGAGGGCACATCCTCAATACCAGGTCCTGGCTACTGCATGGGAATTGGACCCCTCATCTCCCACGGCAGATTCCTGTGGATGGGGATCGGCAGTGCCTGCAACTACTACAACCGGGTATATGGAGAATTCATGCGAGTCTGGATCTCTGGAGAGGAAACACTCATTATCAGCAAGTCCTCAAGTATGTTCCACATAATGAAGCACAATCATTACAGCTCTCGATTCGGCAGCAAACTTGGGCTGCAGTGCATCGGTATGCATGAGAAAGGCATCATATTTAACAACAATCCAGAGCTCTGGAAAACAACTCGACCCTTCTTTATGAAAGCTCTGTCAGGCCCCGGCCTTGTTCGTATGGTCACAGTCTGTGCTGAATCCCTCAAAACACATCTGGACAGGTTGGAGGAGGTGACCAATGAATCGGGCTATGTGGACGTGTTGACCCTTCTGCGTCGTGTCATGCTGGACACCTCTAACACGCTCTTCTTGAGGATCCCTTTGGACGAAAGTGCTATCGTGGTTAAAATCCAAGGTTATTTTGATGCATGGCAAGCTCTCCTCATCAAACCAGACATCTTCTTTAAGATTTCTTGGCTATACAAAAAGTATGAGAAGTCTGTCAAGGATTTGAAAGATGCCATAGAAGTTCTGATAGCAGAAAAAAGACGCAGGATTTCCACAGAAGAGAAACTGGAAGAATGTATGGACTTTGCCACTGAGTTGATTTTAGCAGAGAAACGTGGTGACCTGACAAGAGAGAATGTGAACCAGTGCATATTGGAAATGCTGATCGCAGCTCCTGACACCATGTCTGTCTCTTTGTTCTTCATGCTATTTCTCATTGCAAAGCACCCTAATGTTGAAGAGGCAATAATAAAGGAAATCCAGACTGTTATTGGTGAGAGAGACATAAAGATTGATGATATACAAAAATTAAAAGTGATGGAAAACTTCATTTATGAGAGCATGCGGTACCAGCCTGTCGTGGACTTGGTCATGCGCAAAGCCTTAGAAGATGATGTAATCGATGGCTACCCAGTGAAAAAGGGGACAAACATTATCCTGAATATTGGAAGGATGCACAGACTCGAGTTTTTCCCCAAACCCAATGAATTTACTCTTGAAAATTTTGCAAAGAATGTTCCTTATAGGTACTTTCAGCCATTTGGCTTTGGGCCCCGTGGCTGTGCAGGAAAGTACATCGCCATGGTGATGATGAAAGCCATCCTCGTTACACTTCTGAGACGATTCCACGTGAAGACATTGCAAGGACAGTGTGTTGAGAGCATACAGAAGATACACGACTTGTCCTTGCACCCAGATGAGACTAAAAACATGCTGGAAATGATCTTTACCCCAAGAAACTCAGACAGGTGTCTGGAACACTAG
ORF Protein Sequence MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRNSDRCLEH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T13260-Ab Anti-CYP19A1 monoclonal antibody
    Target Antigen GM-Tg-g-T13260-Ag CYP19A1 protein
    ORF Viral Vector pGMLV000457 Human CYP19A1 Lentivirus plasmid
    ORF Viral Vector pGMAAV001256 Human CYP19A1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000276 Human CYP19A1 Adenovirus plasmid
    ORF Viral Vector vGMLV000457 Human CYP19A1 Lentivirus particle
    ORF Viral Vector vGMAAV001256 Human CYP19A1 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000276 Human CYP19A1 Adenovirus particle


    Target information

    Target ID GM-T13260
    Target Name CYP19A1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1588
    Gene ID 100009712 (Equus caballus), 101094932 (Felis catus), 13075 (Mus musculus), 1588 (Homo sapiens)
    25147 (Rattus norvegicus), 281740 (Bos taurus), 494003 (Canis lupus familiaris), 678697 (Macaca mulatta)
    Gene Symbols & Synonyms CYP19A1,Cyp19a1,CYPXIX,P450AROM,P-450AROM,Ar,ArKO,Int5,Cyp19,Int-5,p450arom,ARO,ARO1,CPV1,CYAR,CYP19,Cyp19a,Aromatase,CYP19P1
    Target Alternative Names ARO,ARO1,Ar,ArKO,Aromatase,CPV1,CYAR,CYP19,CYP19A1,CYP19P1,CYPXIX,Cyp19,Cyp19a,Cyp19a1,Cytochrome P-450AROM,Cytochrome P450 19A1,Estrogen synthase,Int-5,Int5,P-450AROM,P450AROM,p450arom
    Uniprot Accession O46512,P11511,P22443,P28649,P46194,Q5QQX7
    Additional SwissProt Accessions: O46512,P28649,P11511,P22443,P46194,Q5QQX7
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer, Breast cancer
    Disease from KEGG Metabolic pathways, Steroid hormone biosynthesis, Ovarian steroidogenesis
    Gene Ensembl ENSECAG00000020474, ENSMUSG00000032274, ENSG00000137869, ENSBTAG00000014890, ENSCAFG00845024965, ENSMMUG00000002553
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.