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Human FGF21 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_019113.3)
Cat. No.: vGMAAV000245
Pre-made Human FGF21/ Adeno-associated virus particle for FGF21 in-vivo study, mechanism of action (MOA) research and FGF21-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
| Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
| vGMAAV000245 | Human FGF21 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| Research Grade | 1.0E+12VG/ml | |||
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| GMP-like Grade | inquiry | |||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAAV000245 |
| Gene Name | FGF21 |
| Accession Number | NM_019113.3 |
| Gene ID | 26291 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) particle (overexpression) |
| Insert Length | 630 bp |
| Gene Alias | |
| Fluorescent Reporter | Null |
| Mammalian Cell Selection | Null |
| Fusion Tag | Null |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGACTCGGACGAGACCGGGTTCGAGCACTCAGGACTGTGGGTTTCTGTGCTGGCTGGTCTTCTGCTGGGAGCCTGCCAGGCACACCCCATCCCTGACTCCAGTCCTCTCCTGCAATTCGGGGGCCAAGTCCGGCAGCGGTACCTCTACACAGATGATGCCCAGCAGACAGAAGCCCACCTGGAGATCAGGGAGGATGGGACGGTGGGGGGCGCTGCTGACCAGAGCCCCGAAAGTCTCCTGCAGCTGAAAGCCTTGAAGCCGGGAGTTATTCAAATCTTGGGAGTCAAGACATCCAGGTTCCTGTGCCAGCGGCCAGATGGGGCCCTGTATGGATCGCTCCACTTTGACCCTGAGGCCTGCAGCTTCCGGGAGCTGCTTCTTGAGGACGGATACAATGTTTACCAGTCCGAAGCCCACGGCCTCCCGCTGCACCTGCCAGGGAACAAGTCCCCACACCGGGACCCTGCACCCCGAGGACCAGCTCGCTTCCTGCCACTACCAGGCCTGCCCCCCGCACTCCCGGAGCCACCCGGAATCCTGGCCCCCCAGCCCCCCGATGTGGGCTCCTCGGACCCTCTGAGCATGGTGGGACCTTCCCAGGGCCGAAGCCCCAGCTACGCTTCCTGA |
| ORF Protein Sequence | MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T42928-Ab | Anti-FGF21 functional antibody |
| Target Antigen | GM-Tg-g-T42928-Ag | FGF21 protein |
| Cytokine | cks-Tg-g-GM-T42928 | fibroblast growth factor 21 (FGF21) protein & antibody |
| ORF Viral Vector | pGMLP003451 | Human FGF21 Lentivirus plasmid |
| ORF Viral Vector | pGMLV001311 | Human FGF21 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002194 | Human FGF21 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000245 | Human FGF21 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | vGMLP003451 | Human FGF21 Lentivirus particle |
| ORF Viral Vector | vGMLV001311 | Human FGF21 Lentivirus particle |
| ORF Viral Vector | vGMLV002194 | Human FGF21 Lentivirus particle |
| ORF Viral Vector | vGMAAV000245 | Human FGF21 Adeno-associate virus(AAV) particle |
Target information
| Target ID | GM-T42928 |
| Target Name | FGF-21/FGF21 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
26291 |
| Gene ID |
100054542 (Equus caballus), 101080595 (Felis catus), 170580 (Rattus norvegicus), 26291 (Homo sapiens) 484395 (Canis lupus familiaris), 56636 (Mus musculus), 718288 (Macaca mulatta), 785576 (Bos taurus) |
| Gene Symbols & Synonyms | FGF21,Fgf21,FGF8C,Fgf8c |
| Target Alternative Names | FGF-21,FGF21,FGF8C,Fgf21,Fgf8c,Fibroblast growth factor 21 |
| Uniprot Accession |
Q9JJN1,Q9NSA1
Additional SwissProt Accessions: Q9NSA1,Q9JJN1 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | |
| Disease from KEGG | MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Melanoma, Breast cancer, Gastric cancer |
| Gene Ensembl | ENSECAG00000010695, ENSG00000105550, ENSCAFG00845000788, ENSMUSG00000030827, ENSMMUG00000028737, ENSBTAG00000011624 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.