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Human SERPINC1/AT3/AT3D ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_000488.3)
Cat. No.: vGMAAV000149
Pre-made Human SERPINC1/AT3/AT3D Adeno-associated virus particle for SERPINC1 in-vivo study, mechanism of action (MOA) research and SERPINC1-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Serpin C1/Antithrombin III/SERPINC1/ATIII/SERPINC1/AT3 products
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Product information
| Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
| vGMAAV000149 | Human SERPINC1 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| Research Grade | 1.0E+12VG/ml | |||
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| GMP-like Grade | inquiry | |||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAAV000149 |
| Gene Name | SERPINC1 |
| Accession Number | NM_000488.3 |
| Gene ID | 462 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) particle (overexpression) |
| Insert Length | 1395 bp |
| Gene Alias | AT3,AT3D,ATIII,THPH7 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGTATTCCAATGTGATAGGAACTGTAACCTCTGGAAAAAGGAAGGTTTATCTTTTGTCCTTGCTGCTCATTGGCTTCTGGGACTGCGTGACCTGTCACGGGAGCCCTGTGGACATCTGCACAGCCAAGCCGCGGGACATTCCCATGAATCCCATGTGCATTTACCGCTCCCCGGAGAAGAAGGCAACTGAGGATGAGGGCTCAGAACAGAAGATCCCGGAGGCCACCAACCGGCGTGTCTGGGAACTGTCCAAGGCCAATTCCCGCTTTGCTACCACTTTCTATCAGCACCTGGCAGATTCCAAGAATGACAATGATAACATTTTCCTGTCACCCCTGAGTATCTCCACGGCTTTTGCTATGACCAAGCTGGGTGCCTGTAATGACACCCTCCAGCAACTGATGGAGGTATTTAAGTTTGACACCATATCTGAGAAAACATCTGATCAGATCCACTTCTTCTTTGCCAAACTGAACTGCCGACTCTATCGAAAAGCCAACAAATCCTCCAAGTTAGTATCAGCCAATCGCCTTTTTGGAGACAAATCCCTTACCTTCAATGAGACCTACCAGGACATCAGTGAGTTGGTATATGGAGCCAAGCTCCAGCCCCTGGACTTCAAGGAAAATGCAGAGCAATCCAGAGCGGCCATCAACAAATGGGTGTCCAATAAGACCGAAGGCCGAATCACCGATGTCATTCCCTCGGAAGCCATCAATGAGCTCACTGTTCTGGTGCTGGTTAACACCATTTACTTCAAGGGCCTGTGGAAGTCAAAGTTCAGCCCTGAGAACACAAGGAAGGAACTGTTCTACAAGGCTGATGGAGAGTCGTGTTCAGCATCTATGATGTACCAGGAAGGCAAGTTCCGTTATCGGCGCGTGGCTGAAGGCACCCAGGTGCTTGAGTTGCCCTTCAAAGGTGATGACATCACCATGGTCCTCATCTTGCCCAAGCCTGAGAAGAGCCTGGCCAAGGTAGAGAAGGAACTCACCCCAGAGGTGCTGCAAGAGTGGCTGGATGAATTGGAGGAGATGATGCTGGTGGTCCACATGCCCCGCTTCCGCATTGAGGACGGCTTCAGTTTGAAGGAGCAGCTGCAAGACATGGGCCTTGTCGATCTGTTCAGCCCTGAAAAGTCCAAACTCCCAGGTATTGTTGCAGAAGGCCGAGATGACCTCTATGTCTCAGATGCATTCCATAAGGCATTTCTTGAGGTAAATGAAGAAGGCAGTGAAGCAGCTGCAAGTACCGCTGTTGTGATTGCTGGCCGTTCGCTAAACCCCAACAGGGTGACTTTCAAGGCCAACAGGCCTTTCCTGGTTTTTATAAGAGAAGTTCCTCTGAACACTATTATCTTCATGGGCAGAGTAGCCAACCCTTGTGTTAAGTAA |
| ORF Protein Sequence | MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T73476-Ab | Anti-ANT3/ ATIII/ SERPINC1 monoclonal antibody |
| Target Antigen | GM-Tg-g-T73476-Ag | ATIII/SERPINC1 VLP (virus-like particle) |
| ORF Viral Vector | pGMLP002891 | Human SERPINC1 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000149 | Human SERPINC1 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | pGMAAV000297 | Human SERPINC1 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | pGMAAV000501 | Human SERPINC1 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | vGMLP002891 | Human SERPINC1 Lentivirus particle |
| ORF Viral Vector | vGMAAV000149 | Human SERPINC1 Adeno-associate virus(AAV) particle |
| ORF Viral Vector | vGMAAV000297 | Human SERPINC1 Adeno-associate virus(AAV) particle |
| ORF Viral Vector | vGMAAV000501 | Human SERPINC1 Adeno-associate virus(AAV) particle |
Target information
| Target ID | GM-T73476 |
| Target Name | Serpin C1/Antithrombin III/SERPINC1/ATIII |
|
Gene Group Identifier （Target Gene ID in Homo species) |
462 |
| Gene ID |
100061173 (Equus caballus), 101093983 (Felis catus), 11905 (Mus musculus), 304917 (Rattus norvegicus) 462 (Homo sapiens), 480066 (Canis lupus familiaris), 540261 (Bos taurus), 708854 (Macaca mulatta) |
| Gene Symbols & Synonyms | SERPINC1,Serpinc1,AT3,At3,At-3,ATIII,AT3D,THPH7,ATIII-R2,ATIII-T1,ATIII-T2 |
| Target Alternative Names | AT3,AT3D,ATIII,ATIII-R2,ATIII-T1,ATIII-T2,Antithrombin III,Antithrombin-III,At-3,At3,SERPINC1,Serpin C1,Serpinc1,THPH7 |
| Uniprot Accession |
P01008,P32261,P41361
Additional SwissProt Accessions: P32261,P01008,P41361 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | cancer |
| Disease from KEGG | Complement and coagulation cascades |
| Gene Ensembl | ENSECAG00000014493, ENSMUSG00000026715, ENSG00000117601, ENSCAFG00845011264, ENSBTAG00000004362, ENSMMUG00000000629 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.