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Human CASP1/ICE/IL1BC ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001257118.3)
Cat. No.: pGMPC001855
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human CASP1/ICE/IL1BC Non-Viral expression plasmid (overexpression vector) for mouse CASP1 overexpression in unique cell transient transfection and stable cell line development.
Datasheet
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Product Description
| Catalog ID | pGMPC001855 |
| Gene Name | CASP1 |
| Accession Number | NM_001257118.3 |
| Gene ID | 834 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 1215 bp |
| Gene Alias | ICE,IL1BC,P45 |
| Fluorescent Reporter | Null |
| Mammalian Cell Selection | Null |
| Fusion Tag | HA (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGCCGACAAGGTCCTGAAGGAGAAGAGAAAGCTGTTTATCCGTTCCATGGGTGAAGGTACAATAAATGGCTTACTGGATGAATTATTACAGACAAGGGTGCTGAACAAGGAAGAGATGGAGAAAGTAAAACGTGAAAATGCTACAGTTATGGATAAGACCCGAGCTTTGATTGACTCCGTTATTCCGAAAGGGGCACAGGCATGCCAAATTTGCATCACATACATTTGTGAAGAAGACAGTTACCTGGCAGGGACGCTGGGACTCTCAGCAGATCAAACATCTGGAAATTACCTTAATATGCAAGACTCTCAAGGAGTACTTTCTTCCTTTCCAGCTCCTCAGGCAGTGCAGGACAACCCAGCTATGCCCACATCCTCAGGCTCAGAAGGGAATGTCAAGCTTTGCTCCCTAGAAGAAGCTCAAAGGATATGGAAACAAAAGTCGGCAGAGATTTATCCAATAATGGACAAGTCAAGCCGCACACGTCTTGCTCTCATTATCTGCAATGAAGAATTTGACAGTATTCCTAGAAGAACTGGAGCTGAGGTTGACATCACAGGCATGACAATGCTGCTACAAAATCTGGGGTACAGCGTAGATGTGAAAAAAAATCTCACTGCTTCGGACATGACTACAGAGCTGGAGGCATTTGCACACCGCCCAGAGCACAAGACCTCTGACAGCACGTTCCTGGTGTTCATGTCTCATGGTATTCGGGAAGGCATTTGTGGGAAGAAACACTCTGAGCAAGTCCCAGATATACTACAACTCAATGCAATCTTTAACATGTTGAATACCAAGAACTGCCCAAGTTTGAAGGACAAACCGAAGGTGATCATCATCCAGGCCTGCCGTGGTGACAGCCCTGGTGTGGTGTGGTTTAAAGATTCAGTAGGAGTTTCTGGAAACCTATCTTTACCAACTACAGAAGAGTTTGAGGATGATGCTATTAAGAAAGCCCACATAGAGAAGGATTTTATCGCTTTCTGCTCTTCCACACCAGATAATGTTTCTTGGAGACATCCCACAATGGGCTCTGTTTTTATTGGAAGACTCATTGAACATATGCAAGAATATGCCTGTTCCTGTGATGTGGAGGAAATTTTCCGCAAGGTTCGATTTTCATTTGAGCAGCCAGATGGTAGAGCGCAGATGCCCACCACTGAAAGAGTGACTTTGACAAGATGTTTCTACCTCTTCCCAGGACATTAA |
| ORF Protein Sequence | MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T98269-Ab | Anti-CASP1 monoclonal antibody |
| Target Antigen | GM-Tg-g-T98269-Ag | CASP1 protein |
| ORF Viral Vector | pGMLP000487 | Human CASP1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002040 | Human CASP1 Lentivirus plasmid |
| ORF Viral Vector | pGMAP000381 | Human CASP1 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001855 | Human CASP1 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLP000487 | Human CASP1 Lentivirus particle |
| ORF Viral Vector | vGMLV002040 | Human CASP1 Lentivirus particle |
| ORF Viral Vector | vGMAP000381 | Human CASP1 Adenovirus particle |
Target information
| Target ID | GM-T98269 |
| Target Name | Caspase 1/CASP1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
834 |
| Gene ID | 25166 (Rattus norvegicus), 514214 (Bos taurus), 834 (Homo sapiens) |
| Gene Symbols & Synonyms | Casp1,CASP1,Ice,p45,Il1bc,ICE,P45,IL1BC |
| Target Alternative Names | CASP-1,CASP1,Casp1,Caspase 1,Caspase-1,ICE,IL-1 beta-converting enzyme),IL1BC,Ice,Il1bc,Interleukin-1 beta convertase (IL-1BC),Interleukin-1 beta-converting enzyme (ICE,P45,p45 |
| Uniprot Accession |
P29466,P43527
Additional SwissProt Accessions: P43527,P29466 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | cancer, Sepsis |
| Disease from KEGG | NOD-like receptor signaling pathway, C-type lectin receptor signaling pathway, Pathogenic Escherichia coli infection, Pertussis, Legionellosis, Yersinia infection, Influenza A, Lipid and atherosclerosis |
| Gene Ensembl | ENSBTAG00000050239, ENSG00000137752 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.