Human CLU/AAG4/APO-J ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001831.3)

Cat. No.: pGMPC001701
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CLU/AAG4/APO-J Non-Viral expression plasmid (overexpression vector) for mouse CLU overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001701
Gene Name CLU
Accession Number NM_001831.3
Gene ID 1191
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1350 bp
Gene Alias AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGATGAAGACTCTGCTGCTGTTTGTGGGGCTGCTGCTGACCTGGGAGAGTGGGCAGGTCCTGGGGGACCAGACGGTCTCAGACAATGAGCTCCAGGAAATGTCCAATCAGGGAAGTAAGTACGTCAATAAGGAAATTCAAAATGCTGTCAACGGGGTGAAACAGATAAAGACTCTCATAGAAAAAACAAACGAAGAGCGCAAGACACTGCTCAGCAACCTAGAAGAAGCCAAGAAGAAGAAAGAGGATGCCCTAAATGAGACCAGGGAATCAGAGACAAAGCTGAAGGAGCTCCCAGGAGTGTGCAATGAGACCATGATGGCCCTCTGGGAAGAGTGTAAGCCCTGCCTGAAACAGACCTGCATGAAGTTCTACGCACGCGTCTGCAGAAGTGGCTCAGGCCTGGTTGGCCGCCAGCTTGAGGAGTTCCTGAACCAGAGCTCGCCCTTCTACTTCTGGATGAATGGTGACCGCATCGACTCCCTGCTGGAGAACGACCGGCAGCAGACGCACATGCTGGATGTCATGCAGGACCACTTCAGCCGCGCGTCCAGCATCATAGACGAGCTCTTCCAGGACAGGTTCTTCACCCGGGAGCCCCAGGATACCTACCACTACCTGCCCTTCAGCCTGCCCCACCGGAGGCCTCACTTCTTCTTTCCCAAGTCCCGCATCGTCCGCAGCTTGATGCCCTTCTCTCCGTACGAGCCCCTGAACTTCCACGCCATGTTCCAGCCCTTCCTTGAGATGATACACGAGGCTCAGCAGGCCATGGACATCCACTTCCATAGCCCGGCCTTCCAGCACCCGCCAACAGAATTCATACGAGAAGGCGACGATGACCGGACTGTGTGCCGGGAGATCCGCCACAACTCCACGGGCTGCCTGCGGATGAAGGACCAGTGTGACAAGTGCCGGGAGATCTTGTCTGTGGACTGTTCCACCAACAACCCCTCCCAGGCTAAGCTGCGGCGGGAGCTCGACGAATCCCTCCAGGTCGCTGAGAGGTTGACCAGGAAATACAACGAGCTGCTAAAGTCCTACCAGTGGAAGATGCTCAACACCTCCTCCTTGCTGGAGCAGCTGAACGAGCAGTTTAACTGGGTGTCCCGGCTGGCAAACCTCACGCAAGGCGAAGACCAGTACTATCTGCGGGTCACCACGGTGGCTTCCCACACTTCTGACTCGGACGTTCCTTCCGGTGTCACTGAGGTGGTCGTGAAGCTCTTTGACTCTGATCCCATCACTGTGACGGTCCCTGTAGAAGTCTCCAGGAAGAACCCTAAATTTATGGAGACCGTGGCGGAGAAAGCGCTGCAGGAATACCGCAAAAAGCACCGGGAGGAGTGA
ORF Protein Sequence MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-696 Pre-Made Sotevtamab biosimilar, Whole mAb, Anti-CLU/Clusterinm Antibody: Anti-AAG4/APO-J/APOJ/CLI/KUB1/NA1/NA2/SGP-2/SGP2/SP-40/TRPM-2/TRPM2 therapeutic antibody
    Target Antibody GM-Tg-g-T96669-Ab Anti-CLUS/ CLU/ AAG4 functional antibody
    Target Antigen GM-Tg-g-T96669-Ag CLU protein
    ORF Viral Vector pGMLV000313 Human CLU Lentivirus plasmid
    ORF Viral Vector pGMAD000502 Human CLU Adenovirus plasmid
    ORF Viral Vector pGMAD000637 Human CLU Adenovirus plasmid
    ORF Viral Vector pGMPC001701 Human CLU Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004750 Human CLU Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000313 Human CLU Lentivirus particle
    ORF Viral Vector vGMAD000502 Human CLU Adenovirus particle
    ORF Viral Vector vGMAD000637 Human CLU Adenovirus particle


    Target information

    Target ID GM-T96669
    Target Name CLU/Clusterin
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1191
    Gene ID 100034172 (Equus caballus), 101092846 (Felis catus), 1191 (Homo sapiens), 12759 (Mus musculus)
    24854 (Rattus norvegicus), 442971 (Canis lupus familiaris), 677866 (Macaca mulatta)
    Gene Symbols & Synonyms CLU,Clu,CLI,AAG4,APOJ,CLU1,CLU2,KUB1,SGP2,APO-J,SGP-2,SP-40,TRPM2,TRPM-2,NA1/NA2,Cli,ApoJ,Sgp2,Sgp-2,Sugp-2,D14Ucla3,DAG,SP40,Trpm2,Trpmb,TRPM2B,RATTRPM2B,GP80
    Target Alternative Names 40,AAG4,APO-J,APOJ,Aging-associated gene 4 protein,ApoJ,Apolipoprotein J (Apo-J),CLI,CLU,CLU1,CLU2,Cli,Clu,Clusterin,Complement cytolysis inhibitor (CLI),Complement-associated protein SP-40,D14Ucla3,DAG,GP80,KUB1,Ku70-binding protein 1,NA1/NA2,RATTRPM2B,SGP-2,SGP2,SP-40,SP40,Sgp-2,Sgp2,Sugp-2,Sulfated glycoprotein 2 (SGP-2),TRPM-2,TRPM2,TRPM2B,Testosterone-repressed prostate message 2 (TRPM-2),Trpm2,Trpmb
    Uniprot Accession P05371,P10909,P25473,Q06890,Q29482
    Additional SwissProt Accessions: Q29482,P10909,Q06890,P05371,P25473
    Uniprot Entry Name
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, INN Index
    Disease cancer, leukemia patients, Acute kidney failure, Dent disease, Type 2 diabetes mellitus
    Disease from KEGG Complement and coagulation cascades
    Gene Ensembl ENSECAG00000007010, ENSG00000120885, ENSMUSG00000022037, ENSCAFG00845010565, ENSMMUG00000021516
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.