Human RUNX1/AML1/AML1-EVI-1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001001890.3)

Cat. No.: pGMPC001636
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human RUNX1/AML1/AML1-EVI-1 Non-Viral expression plasmid (overexpression vector) for mouse RUNX1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001636
Gene Name RUNX1
Accession Number NM_001001890.3
Gene ID 861
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1362 bp
Gene Alias AML1,AML1-EVI-1,AMLCR1,CBF2alpha,CBFA2,EVI-1,PEBP2aB,PEBP2alpha
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGTATCCCCGTAGATGCCAGCACGAGCCGCCGCTTCACGCCGCCTTCCACCGCGCTGAGCCCAGGCAAGATGAGCGAGGCGTTGCCGCTGGGCGCCCCGGACGCCGGCGCTGCCCTGGCCGGCAAGCTGAGGAGCGGCGACCGCAGCATGGTGGAGGTGCTGGCCGACCACCCGGGCGAGCTGGTGCGCACCGACAGCCCCAACTTCCTCTGCTCCGTGCTGCCTACGCACTGGCGCTGCAACAAGACCCTGCCCATCGCTTTCAAGGTGGTGGCCCTAGGGGATGTTCCAGATGGCACTCTGGTCACTGTGATGGCTGGCAATGATGAAAACTACTCGGCTGAGCTGAGAAATGCTACCGCAGCCATGAAGAACCAGGTTGCAAGATTTAATGACCTCAGGTTTGTCGGTCGAAGTGGAAGAGGGAAAAGCTTCACTCTGACCATCACTGTCTTCACAAACCCACCGCAAGTCGCCACCTACCACAGAGCCATCAAAATCACAGTGGATGGGCCCCGAGAACCTCGAAGACATCGGCAGAAACTAGATGATCAGACCAAGCCCGGGAGCTTGTCCTTTTCCGAGCGGCTCAGTGAACTGGAGCAGCTGCGGCGCACAGCCATGAGGGTCAGCCCACACCACCCAGCCCCCACGCCCAACCCTCGTGCCTCCCTGAACCACTCCACTGCCTTTAACCCTCAGCCTCAGAGTCAGATGCAGGATACAAGGCAGATCCAACCATCCCCACCGTGGTCCTACGATCAGTCCTACCAATACCTGGGATCCATTGCCTCTCCTTCTGTGCACCCAGCAACGCCCATTTCACCTGGACGTGCCAGCGGCATGACAACCCTCTCTGCAGAACTTTCCAGTCGACTCTCAACGGCACCCGACCTGACAGCGTTCAGCGACCCGCGCCAGTTCCCCGCGCTGCCCTCCATCTCCGACCCCCGCATGCACTATCCAGGCGCCTTCACCTACTCCCCGACGCCGGTCACCTCGGGCATCGGCATCGGCATGTCGGCCATGGGCTCGGCCACGCGCTACCACACCTACCTGCCGCCGCCCTACCCCGGCTCGTCGCAAGCGCAGGGAGGCCCGTTCCAAGCCAGCTCGCCCTCCTACCACCTGTACTACGGCGCCTCGGCCGGCTCCTACCAGTTCTCCATGGTGGGCGGCGAGCGCTCGCCGCCGCGCATCCTGCCGCCCTGCACCAACGCCTCCACCGGCTCCGCGCTGCTCAACCCCAGCCTCCCGAACCAGAGCGACGTGGTGGAGGCCGAGGGCAGCCACAGCAACTCCCCCACCAACATGGCGCCCTCCGCGCGCCTGGAGGAGGCCGTGTGGAGGCCCTACTGA
ORF Protein Sequence MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T43711-Ab Anti-RUNX1 monoclonal antibody
    Target Antigen GM-Tg-g-T43711-Ag RUNX1 protein
    ORF Viral Vector pGMLV000314 Human RUNX1 Lentivirus plasmid
    ORF Viral Vector pGMLV000843 Human RUNX1 Lentivirus plasmid
    ORF Viral Vector pGMPC001443 Human RUNX1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001636 Human RUNX1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000314 Human RUNX1 Lentivirus particle
    ORF Viral Vector vGMLV000843 Human RUNX1 Lentivirus particle


    Target information

    Target ID GM-T43711
    Target Name RUNX1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		861
    Gene ID 100051950 (Equus caballus), 101084898 (Felis catus), 12394 (Mus musculus), 487746 (Canis lupus familiaris)
    50662 (Rattus norvegicus), 529631 (Bos taurus), 696749 (Macaca mulatta), 861 (Homo sapiens)
    Gene Symbols & Synonyms RUNX1,Runx1,AML1,Cbfa2,Pebp2a2,Pebpa2b,CBF-alpha-2,Aml1,PEA2-alpha,PEBP2-alpha,CBFA2,EVI-1,AMLCR1,PEBP2aB,CBF2alpha,AML1-EVI-1,PEBP2alpha
    Target Alternative Names AML1,AML1-EVI-1,AMLCR1,Acute myeloid leukemia 1 protein,Aml1,CBF-alpha-2,CBF2alpha,CBFA2,Cbfa2,Core-binding factor subunit alpha-2 (CBF-alpha-2),EVI-1,Oncogene AML-1,PEA2-alpha,PEBP2-alpha,PEBP2-alpha B),PEBP2aB,PEBP2alpha,Pebp2a2,Pebpa2b,Polyomavirus enhancer-binding protein 2 alpha B subunit (PEA2-alpha B,RUNX1,Runt-related transcription factor 1,Runx1,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core-binding factor alpha B subunit
    Uniprot Accession Q01196,Q03347,Q63046
    Additional SwissProt Accessions: Q03347,Q63046,Q01196
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Tight junction, Th17 cell differentiation, Pathways in cancer, Chronic myeloid leukemia, Acute myeloid leukemia
    Gene Ensembl ENSECAG00000003462, ENSMUSG00000022952, ENSCAFG00845026139, ENSBTAG00000004742, ENSMMUG00000001649, ENSG00000159216
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.