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Human SMAD2/CHTD8/hMAD-2 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_005901)
Cat. No.: pGMPC001609
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human SMAD2/CHTD8/hMAD-2 Non-Viral expression plasmid (overexpression vector) for mouse SMAD2 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC001609 |
| Gene Name | SMAD2 |
| Accession Number | NM_005901 |
| Gene ID | 4087 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 1404 bp |
| Gene Alias | CHTD8,hMAD-2,hSMAD2,JV18,JV18-1,LDS6,MADH2,MADR2 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGATCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGAAACGCCACCTCCTGGATATATCAGTGAAGATGGAGAAACAAGTGACCAACAGTTGAATCAAAGTATGGACACAGGCTCTCCAGCAGAACTATCTCCTACTACTCTTTCCCCTGTTAATCATAGCTTGGATTTACAGCCAGTTACTTACTCAGAACCTGCATTTTGGTGTTCGATAGCATATTATGAATTAAATCAGAGGGTTGGAGAAACCTTCCATGCATCACAGCCCTCACTCACTGTAGATGGCTTTACAGACCCATCAAATTCAGAGAGGTTCTGCTTAGGTTTACTCTCCAATGTTAACCGAAATGCCACGGTAGAAATGACAAGAAGGCATATAGGAAGAGGAGTGCGCTTATACTACATAGGTGGGGAAGTTTTTGCTGAGTGCCTAAGTGATAGTGCAATCTTTGTGCAGAGCCCCAATTGTAATCAGAGATATGGCTGGCACCCTGCAACAGTGTGTAAAATTCCACCAGGCTGTAATCTGAAGATCTTCAACAACCAGGAATTTGCTGCTCTTCTGGCTCAGTCTGTTAATCAGGGTTTTGAAGCCGTCTATCAGCTAACTAGAATGTGCACCATAAGAATGAGTTTTGTGAAAGGGTGGGGAGCAGAATACCGAAGGCAGACGGTAACAAGTACTCCTTGCTGGATTGAACTTCATCTGAATGGACCTCTACAGTGGTTGGACAAAGTATTAACTCAGATGGGATCCCCTTCAGTGCGTTGCTCAAGCATGTCATAA |
| ORF Protein Sequence | MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-IP1753-Ab | Anti-SMAD2 monoclonal antibody |
| Target Antigen | GM-Tg-g-IP1753-Ag | SMAD2 protein |
| Cytokine | cks-Tg-g-GM-IP1753 | SMAD family member 2 (SMAD2) protein & antibody |
| ORF Viral Vector | pGMLP001353 | Human SMAD2 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000190 | Human SMAD2 Adenovirus plasmid |
| ORF Viral Vector | pGMLP-SPh-044 | Human SMAD2 Lentivirus plasmid |
| ORF Viral Vector | pGMAP-SPh-184 | Human SMAD2 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001202 | Human SMAD2 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC001609 | Human SMAD2 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLP001353 | Human SMAD2 Lentivirus particle |
| ORF Viral Vector | vGMAD000190 | Human SMAD2 Adenovirus particle |
| ORF Viral Vector | vGMLP-SPh-044 | Human SMAD2 Lentivirus particle |
| ORF Viral Vector | vGMAP-SPh-184 | Human SMAD2 Adenovirus particle |
Target information
| Target ID | GM-IP1753 |
| Target Name | SMAD2 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
4087 |
| Gene ID |
100033843 (Equus caballus), 101087179 (Felis catus), 17126 (Mus musculus), 29357 (Rattus norvegicus) 4087 (Homo sapiens), 480144 (Canis lupus familiaris), 516010 (Bos taurus), 697581 (Macaca mulatta) |
| Gene Symbols & Synonyms | SMAD2,Smad2,Madh2,Madr2,mMad2,Smad-2,7120426M23Rik,JV18,LDS6,CHTD8,MADH2,MADR2,JV18-1,hMAD-2,hSMAD2 |
| Target Alternative Names | 7120426M23Rik,CHTD8,JV18,JV18-1,LDS6,MAD homolog 2,MADH2,MADR2,Mad-related protein 2 (hMAD-2),Madh2,Madr2,Mothers against DPP homolog 2,Mothers against decapentaplegic homolog 2,SMAD family member 2 (SMAD 2,SMAD2,Smad-2,Smad2,hMAD-2,hSMAD2,hSMAD2),mMad2 |
| Uniprot Accession |
O70436,Q15796,Q1W668,Q62432
Additional SwissProt Accessions: Q62432,O70436,Q15796,Q1W668 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Cellular senescence, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th17 cell differentiation, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Chagas disease, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Pancreatic cancer, Hepatocellular carcinoma, Gastric cancer, Inflammatory bowel disease |
| Gene Ensembl | ENSECAG00000015132, ENSMUSG00000024563, ENSG00000175387, ENSCAFG00845002338, ENSBTAG00000039916, ENSMMUG00000007816 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
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