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Human BIRC5/API4/EPR-1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001168.3)
Cat. No.: pGMPC001525
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human BIRC5/API4/EPR-1 Non-Viral expression plasmid (overexpression vector) for mouse BIRC5 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC001525 |
| Gene Name | BIRC5 |
| Accession Number | NM_001168.3 |
| Gene ID | 332 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 429 bp |
| Gene Alias | API4,EPR-1 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAGCAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGA |
| ORF Protein Sequence | MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAAMD |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T02677-Ab | Anti-BIRC5 monoclonal antibody |
| Target Antigen | GM-Tg-g-T02677-Ag | BIRC5 protein |
| ORF Viral Vector | pGMAP000202 | Human BIRC5 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001492 | Human BIRC5 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | pGMPC001525 | Human BIRC5 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMAP000202 | Human BIRC5 Adenovirus particle |
Target information
| Target ID | GM-T02677 |
| Target Name | SURVIVIN/BIRC5 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
332 |
| Gene ID |
100050808 (Equus caballus), 11799 (Mus musculus), 332 (Homo sapiens), 414925 (Bos taurus) 442936 (Canis lupus familiaris), 493835 (Felis catus), 64041 (Rattus norvegicus), 709565 (Macaca mulatta) |
| Gene Symbols & Synonyms | BIRC5,Birc5,Api4,TIAP,AAC-11,survivin40,API4,EPR-1,AP14 |
| Target Alternative Names | AAC-11,AP14,API4,Api4,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,BIRC5,Baculoviral IAP repeat-containing protein 5,Birc5,EPR-1,SURVIVIN,TIAP,survivin40 |
| Uniprot Accession |
O15392,O70201,Q6I6F4,Q6J1J1,Q8I009,Q9JHY7
Additional SwissProt Accessions: O70201,O15392,Q6J1J1,Q8I009,Q6I6F4,Q9JHY7 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | cancer, Breast Cancer, Malignant neoplasm of bladder |
| Disease from KEGG | Apoptosis, Apoptosis - multiple species, Hippo signaling pathway, Hepatitis B, Pathways in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer |
| Gene Ensembl | ENSMUSG00000017716, ENSG00000089685, ENSBTAG00000013573, ENSMMUG00000013767 |
| Target Classification | Checkpoint-Immuno Oncology |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.