Human XIAP/API3/BIRC4 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001167)

Cat. No.: pGMPC001434
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human XIAP/API3/BIRC4 Non-Viral expression plasmid (overexpression vector) for mouse XIAP overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001434
Gene Name XIAP
Accession Number NM_001167
Gene ID 331
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1494 bp
Gene Alias API3,BIRC4,hIAP-3,hIAP3,IAP-3,ILP1,MIHA,XLP2
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAGAAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTCCTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCGTGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTGGAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATAGTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATCTGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTTTGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGTATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCCCAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCTTTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACAGGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAATCTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCATCCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACAAGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCTTTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATGCTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACAATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCATCACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATACGAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTGGGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACAGTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGCTAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCGTTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGTGTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAA
ORF Protein Sequence MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0058-Ab Anti-XIAP monoclonal antibody
    Target Antigen GM-Tg-g-IP0058-Ag XIAP protein
    ORF Viral Vector pGMLP002221 Human XIAP Lentivirus plasmid
    ORF Viral Vector pGMLV000630 Human XIAP Lentivirus plasmid
    ORF Viral Vector pGMPC001434 Human XIAP Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002221 Human XIAP Lentivirus particle
    ORF Viral Vector vGMLV000630 Human XIAP Lentivirus particle


    Target information

    Target ID GM-IP0058
    Target Name XIAP
    Gene Group Identifier
    （Target Gene ID in Homo species)         		331
    Gene ID 100060870 (Equus caballus), 101090594 (Felis catus), 11798 (Mus musculus), 281647 (Bos taurus)
    331 (Homo sapiens), 442989 (Canis lupus familiaris), 63879 (Rattus norvegicus), 698057 (Macaca mulatta)
    Gene Symbols & Synonyms XIAP,Xiap,Aipa,Api3,IAP3,MIHA,Birc4,ILP-1,1110015C02Rik,BIRC4,API3,ILP1,XLP2,IAP-3,hIAP3,hIAP-3,riap3
    Target Alternative Names 1110015C02Rik,API3,Aipa,Api3,BIRC4,Baculoviral IAP repeat-containing protein 4,Birc4,E3 ubiquitin-protein ligase XIAP,IAP-3,IAP-like protein (ILP,IAP3,ILP-1,ILP1,Inhibitor of apoptosis protein 3 (IAP-3,MIHA,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein (X-linked IAP),XIAP,XLP2,Xiap,hIAP-3,hIAP3,hIAP3),hILP),riap3
    Uniprot Accession P98170,Q60989,Q9R0I6
    Additional SwissProt Accessions: Q60989,P98170,Q9R0I6
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease cancer
    Disease from KEGG NF-kappa B signaling pathway, Apoptosis, Apoptosis - multiple species, Focal adhesion, NOD-like receptor signaling pathway, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Small cell lung cancer
    Gene Ensembl ENSECAG00000020071, ENSMUSG00000025860, ENSBTAG00000040350, ENSG00000101966, ENSCAFG00845025680, ENSMMUG00000032353
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


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