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Human PDCD1/CD279/hPD-1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_005018.2)
Cat. No.: pGMPC000931
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human PDCD1/CD279/hPD-1 Non-Viral expression plasmid (overexpression vector) for mouse PDCD1 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC000931 |
| Gene Name | PDCD1 |
| Accession Number | NM_005018.2 |
| Gene ID | 5133 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 867 bp |
| Gene Alias | CD279,hPD-1,hPD-l,hSLE1,PD-1,PD1,SLEB2 |
| Fluorescent Reporter | EGFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | HA (C-Terminal) |
| Promoter | EF1 |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGCAGATCCCACAGGCGCCCTGGCCAGTCGTCTGGGCGGTGCTACAACTGGGCTGGCGGCCAGGATGGTTCTTAGACTCCCCAGACAGGCCCTGGAACCCCCCCACCTTCTCCCCAGCCCTGCTCGTGGTGACCGAAGGGGACAACGCCACCTTCACCTGCAGCTTCTCCAACACATCGGAGAGCTTCGTGCTAAACTGGTACCGCATGAGCCCCAGCAACCAGACGGACAAGCTGGCCGCCTTCCCCGAGGACCGCAGCCAGCCCGGCCAGGACTGCCGCTTCCGTGTCACACAACTGCCCAACGGGCGTGACTTCCACATGAGCGTGGTCAGGGCCCGGCGCAATGACAGCGGCACCTACCTCTGTGGGGCCATCTCCCTGGCCCCCAAGGCGCAGATCAAAGAGAGCCTGCGGGCAGAGCTCAGGGTGACAGAGAGAAGGGCAGAAGTGCCCACAGCCCACCCCAGCCCCTCACCCAGGCCAGCCGGCCAGTTCCAAACCCTGGTGGTTGGTGTCGTGGGCGGCCTGCTGGGCAGCCTGGTGCTGCTAGTCTGGGTCCTGGCCGTCATCTGCTCCCGGGCCGCACGAGGGACAATAGGAGCCAGGCGCACCGGCCAGCCCCTGAAGGAGGACCCCTCAGCCGTGCCTGTGTTCTCTGTGGACTATGGGGAGCTGGATTTCCAGTGGCGAGAGAAGACCCCGGAGCCCCCCGTGCCCTGTGTCCCTGAGCAGACGGAGTATGCCACCATTGTCTTTCCTAGCGGAATGGGCACCTCATCCCCCGCCCGCAGGGGCTCAGCTGACGGCCCTCGGAGTGCCCAGCCACTGAGGCCTGAGGATGGACACTGCTCTTGGCCCCTCTGA |
| ORF Protein Sequence | MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGSLVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL |
Reference
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Associated products
Target information
| Target ID | GM-T59631 |
| Target Name | PD-1/CD279/PDCD1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
5133 |
| Gene ID |
100067948 (Equus caballus), 100135770 (Felis catus), 100135775 (Macaca mulatta), 18566 (Mus musculus) 301626 (Rattus norvegicus), 486213 (Canis lupus familiaris), 5133 (Homo sapiens), 613842 (Bos taurus) |
| Gene Symbols & Synonyms | PDCD1,Pdcd1,PD-1,PD1,Pdc1,Ly101,CD279,SLEB2,hPD-1,hPD-l,hSLE1,AIMTBS |
| Target Alternative Names | PD-1, CD279, PDCD1,Programmed cell death protein 1,Protein PD-1, hPD-1,PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,AIMTBS |
| Uniprot Accession |
Q02242,Q15116
Additional SwissProt Accessions: Q02242,Q15116 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index |
| Disease | cancer |
| Disease from KEGG | Cell adhesion molecules, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer |
| Gene Ensembl | ENSECAG00000023275, ENSMMUG00000063159, ENSMUSG00000026285, ENSCAFG00845024308, ENSG00000188389, ENSBTAG00000011543 |
| Target Classification | Checkpoint-Immuno Oncology, Cytokine Receptor, Pathway, Tumor-associated antigen (TAA) |
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