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Human CCR4/CC-CKR-4/CD194 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_005508.5)
Cat. No.: pGMPC000641
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human CCR4/CC-CKR-4/CD194 Non-Viral expression plasmid (overexpression vector) for mouse CCR4 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC000641 |
| Gene Name | CCR4 |
| Accession Number | NM_005508.5 |
| Gene ID | 1233 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 1083 bp |
| Gene Alias | CC-CKR-4,CD194,ChemR13,CKR4,CMKBR4,HGCN:14099,K5-5 |
| Fluorescent Reporter | Null |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | Null |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAACCCCACGGATATAGCAGACACCACCCTCGATGAAAGCATATACAGCAATTACTATCTGTATGAAAGTATCCCCAAGCCTTGCACCAAAGAAGGCATCAAGGCATTTGGGGAGCTCTTCCTGCCCCCACTGTATTCCTTGGTTTTTGTATTTGGTCTGCTTGGAAATTCTGTGGTGGTTCTGGTCCTGTTCAAATACAAGCGGCTCAGGTCCATGACTGATGTGTACCTGCTCAACCTTGCCATCTCGGATCTGCTCTTCGTGTTTTCCCTCCCTTTTTGGGGCTACTATGCAGCAGACCAGTGGGTTTTTGGGCTAGGTCTGTGCAAGATGATTTCCTGGATGTACTTGGTGGGCTTTTACAGTGGCATATTCTTTGTCATGCTCATGAGCATTGATAGATACCTGGCAATTGTGCACGCGGTGTTTTCCTTGAGGGCAAGGACCTTGACTTATGGGGTCATCACCAGTTTGGCTACATGGTCAGTGGCTGTGTTCGCCTCCCTTCCTGGCTTTCTGTTCAGCACTTGTTATACTGAGCGCAACCATACCTACTGCAAAACCAAGTACTCTCTCAACTCCACGACGTGGAAGGTTCTCAGCTCCCTGGAAATCAACATTCTCGGATTGGTGATCCCCTTAGGGATCATGCTGTTTTGCTACTCCATGATCATCAGGACCTTGCAGCATTGTAAAAATGAGAAGAAGAACAAGGCGGTGAAGATGATCTTTGCCGTGGTGGTCCTCTTCCTTGGGTTCTGGACACCTTACAACATAGTGCTCTTCCTAGAGACCCTGGTGGAGCTAGAAGTCCTTCAGGACTGCACCTTTGAAAGATACTTGGACTATGCCATCCAGGCCACAGAAACTCTGGCTTTTGTTCACTGCTGCCTTAATCCCATCATCTACTTTTTTCTGGGGGAGAAATTTCGCAAGTACATCCTACAGCTCTTCAAAACCTGCAGGGGCCTTTTTGTGCTCTGCCAATACTGTGGGCTCCTCCAAATTTACTCTGCTGACACCCCCAGCTCATCTTACACGCAGTCCACCATGGATCATGATCTCCATGATGCTCTGTAG |
| ORF Protein Sequence | MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-354 | Pre-Made Mogamulizumab biosimilar, Whole mAb, Anti-CCR4 Antibody: Anti-CKR4/K5-5/CD194/CMKBR4/ChemR13/CC-CKR-4/HGCN:14099 therapeutic antibody |
| Target Antibody | GM-Tg-g-T06955-Ab | Anti-CCR4/ CC-CKR-4/ CD194 monoclonal antibody |
| Target Antigen | GM-Tg-g-T06955-Ag | CCR4 VLP (virus-like particle) |
| Cytokine | cks-Tg-g-GM-T06955 | chemokine (C-C motif) receptor 4 (CCR4) protein & antibody |
| ORF Viral Vector | pGMLP002020 | Human CCR4 Lentivirus plasmid |
| ORF Viral Vector | pGMPC000641 | Human CCR4 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLP002020 | Human CCR4 Lentivirus particle |
Target information
| Target ID | GM-T06955 |
| Target Name | CCR4/CD194 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
1233 |
| Gene ID |
100056549 (Equus caballus), 102900629 (Felis catus), 1233 (Homo sapiens), 12773 (Mus musculus) 171054 (Rattus norvegicus), 403541 (Canis lupus familiaris), 408019 (Bos taurus), 705457 (Macaca mulatta) |
| Gene Symbols & Synonyms | CCR4,Ccr4,CKR4,K5-5,CD194,CMKBR4,ChemR13,CC-CKR-4,HGCN:14099,LESTR,Sdf1r,CHEMR1,Cmkbr4,C-C CKR-4 |
| Target Alternative Names | C-C CKR-4,C-C chemokine receptor type 4,CC-CKR-4,CCR-4,CCR4,CD194,CHEMR1,CKR4,CMKBR4,Ccr4,ChemR13,Cmkbr4,HGCN:14099,K5-5,LESTR,Sdf1r |
| Uniprot Accession |
P51679,P51680,Q8MJW8
Additional SwissProt Accessions: P51679,P51680,Q8MJW8 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Kaposi sarcoma-associated herpesvirus infection |
| Gene Ensembl | ENSECAG00000005023, ENSG00000183813, ENSMUSG00000047898, ENSCAFG00845023571, ENSBTAG00000034883, ENSMMUG00000022661 |
| Target Classification | GPCR, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.