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Human ERBB3/c-erbB-3/c-erbB3 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (BC002706)
Cat. No.: pGMPC000619
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human ERBB3/c-erbB-3/c-erbB3 Non-Viral expression plasmid (overexpression vector) for mouse ERBB3 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC000619 |
| Gene Name | ERBB3 |
| Accession Number | BC002706 |
| Gene ID | 2065 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 996 bp |
| Gene Alias | c-erbB-3,c-erbB3,ErbB-3,erbB3-S,HER3,MDA-BF-1,p180-ErbB3,p45-sErbB3,p85-sErbB3 |
| Fluorescent Reporter | EGFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAGGGCGAACGACGCTCTGCAGGTGCTGGGCTTGCTTTTCAGCCTGGCCCGGGGCTCCGAGGTGGGCAACTCTCAGGCAGTGTGTCCTGGGACTCTGAATGGCCTGAGTGTGACCGGCGATGCTGAGAACCAATACCAGACACTGTACAAGCTCTACGAGAGGTGTGAGGTGGTGATGGGGAACCTTGAGATTGTGCTCACGGGACACAATGCCGACCTCTCCTTCCTGCAGTGGATTCGAGAAGTGACAGGCTATGTCCTCGTGGCCATGAATGAATTCTCTACTCTACCATTGCCCAACCTCCGCGTGGTGCGAGGGACCCAGGTCTACGATGGGAAGTTTGCCATCTTCGTCATGTTGAACTATAACACCAACTCCAGCCACGCTCTGCGCCAGCTCCGCTTGACTCAGCTCACCGAGATTCTGTCAGGGGGTGTTTATATTGAGAAGAACGATAAGCTTTGTCACATGGACACAATTGACTGGAGGGACATCGTGAGGGACCGAGATGCTGAGATAGTGGTGAAGGACAATGGCAGAAGCTGTCCCCCCTGTCATGAGGTTTGCAAGGGGCGATGCTGGGGTCCTGGATCAGAAGACTGCCAGACATTGACCAAGACCATCTGTGCTCCTCAGTGTAATGGTCACTGCTTTGGGCCCAACCCCAACCAGTGCTGCCATGATGAGTGTGCCGGGGGCTGCTCAGGCCCTCAGGACACAGACTGCTTTGCCTGCCGGCACTTCAATGACAGTGGAGCCTGTGTACCTCGCTGTCCACAGCCTCTTGTCTACAACAAGCTAACTTTCCAGCTGGAACCCAATCCCCACACCAAGTATCAGTATGGAGGAGTTTGTGTAGCCAGCTGTCCCCATAACTTTGTGGTGGATCAAACATCCTGTGTCAGGGCCTGTCCTCCTGACAAGATGGAAGTAGATAAAAATGGGCTCAAGATGTGTGAGCCTTGTGGGGGACTATGTCCCAAAGCCTTTTAA |
| ORF Protein Sequence | MRANDALQVLGLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKAF |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T86350 |
| Target Name | ERBB3/ErbB3/HER3/Erbb-3 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
2065 |
| Gene ID |
100059216 (Equus caballus), 101085388 (Felis catus), 13867 (Mus musculus), 2065 (Homo sapiens) 29496 (Rattus norvegicus), 481105 (Canis lupus familiaris), 711407 (Macaca mulatta), 785655 (Bos taurus) |
| Gene Symbols & Synonyms | ERBB3,Erbb3,Her3,Erbb-3,Erbb3r,HER3,FERLK,LCCS2,VSCN1,ErbB-3,c-erbB3,erbB3-S,MDA-BF-1,c-erbB-3,p180-ErbB3,p45-sErbB3,p85-sErbB3,nuc-ErbB3 |
| Target Alternative Names | ERBB3,ErbB-3,ErbB3,Erbb-3,Erbb3,Erbb3r,FERLK,HER3,Her3,LCCS2,MDA-BF-1,Proto-oncogene-like protein c-ErbB-3,Receptor tyrosine-protein kinase erbB-3,Tyrosine kinase-type cell surface receptor HER3,VSCN1,c-erbB-3,c-erbB3,erbB3-S,nuc-ErbB3,p180-ErbB3,p45-sErbB3,p85-sErbB3 |
| Uniprot Accession |
P21860,Q61526,Q62799
Additional SwissProt Accessions: Q61526,P21860,Q62799 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | cancer, Non-Small Cell Lung Cancer, Prostate Cancer |
| Disease from KEGG | EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Proteoglycans in cancer |
| Gene Ensembl | ENSECAG00000024374, ENSMUSG00000018166, ENSG00000065361, ENSCAFG00845006158, ENSMMUG00000020758, ENSBTAG00000010444 |
| Target Classification | Cytokine Receptor, Checkpoint-Immuno Oncology |
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