Human PDK1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_002610)

Cat. No.: pGMPC000371
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PDK1/ Non-Viral expression plasmid (overexpression vector) for mouse PDK1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000371
Gene Name PDK1
Accession Number NM_002610
Gene ID 5163
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1311 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag HA (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGGCTGGCGCGGCTGCTTCGCGGAGCCGCCTTGGCCGGCCCGGGCCCGGGGCTGCGCGCCGCCGGCTTCAGCCGCAGCTTCAGCTCGGACTCGGGCTCCAGCCCGGCGTCCGAGCGCGGCGTTCCGGGCCAGGTGGACTTCTACGCGCGCTTCTCGCCGTCCCCGCTCTCCATGAAGCAGTTCCTGGACTTCGGATCAGTGAATGCTTGTGAAAAGACCTCATTTATGTTTCTGCGGCAAGAGTTGCCTGTCAGACTGGCAAATATAATGAAAGAAATAAGTCTCCTTCCAGATAATCTTCTCAGGACACCATCCGTTCAATTGGTACAAAGCTGGTATATCCAGAGTCTTCAGGAGCTTCTTGATTTTAAGGACAAAAGTGCTGAGGATGCTAAAGCTATTTATGACTTTACAGATACTGTGATACGGATCAGAAACCGACACAATGATGTCATTCCCACAATGGCCCAGGGTGTGATTGAATACAAGGAGAGCTTTGGGGTGGATCCTGTCACCAGCCAGAATGTTCAGTACTTTTTGGATCGATTCTACATGAGTCGCATTTCAATTAGAATGTTACTCAATCAGCACTCTTTATTGTTTGGTGGAAAAGGCAAAGGAAGTCCATCTCATCGAAAACACATTGGAAGCATAAATCCAAACTGCAATGTACTTGAAGTTATTAAAGATGGCTATGAAAATGCTAGGCGTCTGTGTGATTTGTATTATATTAACTCTCCCGAACTAGAACTTGAAGAACTAAATGCAAAATCACCAGGACAGCCAATACAAGTGGTTTATGTACCATCCCATCTCTATCACATGGTGTTTGAACTTTTCAAGAATGCAATGAGAGCCACTATGGAACACCATGCCAACAGAGGTGTTTACCCCCCTATTCAAGTTCATGTCACGCTGGGTAATGAGGATTTGACTGTGAAGATGAGTGACCGAGGAGGTGGCGTTCCTTTGAGGAAAATTGACAGACTTTTCAACTACATGTATTCAACTGCACCAAGACCTCGTGTTGAGACCTCCCGCGCAGTGCCTCTGGCTGGTTTTGGTTATGGATTGCCCATATCACGTCTTTACGCACAATACTTCCAAGGAGACCTGAAGCTGTATTCCCTAGAGGGTTACGGGACAGATGCAGTTATCTACATTAAGGCTCTGTCAACAGACTCAATAGAAAGACTCCCAGTGTATAACAAAGCTGCCTGGAAGCATTACAACACCAACCACGAGGCTGATGACTGGTGCGTCCCCAGCAGAGAACCCAAAGACATGACGACGTTCCGCAGTGCCTAG
ORF Protein Sequence MRLARLLRGAALAGPGPGLRAAGFSRSFSSDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T15776-Ab Anti-PDHK1 monoclonal antibody
    Target Antigen GM-Tg-g-T15776-Ag PDHK1/PDK1 protein
    ORF Viral Vector pGMLP005316 Human PDK1 Lentivirus plasmid
    ORF Viral Vector pGMPC000371 Human PDK1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005316 Human PDK1 Lentivirus particle


    Target information

    Target ID GM-T15776
    Target Name PDK1/PDHK1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5163
    Gene ID 100064091 (Equus caballus), 101092705 (Felis catus), 116551 (Rattus norvegicus), 228026 (Mus musculus)
    476828 (Canis lupus familiaris), 5163 (Homo sapiens), 528655 (Bos taurus), 697772 (Macaca mulatta)
    Gene Symbols & Synonyms PDK1,Pdk1,B830012B01,D530020C15Rik
    Target Alternative Names PDK1, PDHK1,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial,Pyruvate dehydrogenase kinase isoform 1 (PDH kinase 1)
    Uniprot Accession Q15118,Q63065,Q8BFP9
    Additional SwissProt Accessions: Q63065,Q8BFP9,Q15118
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG HIF-1 signaling pathway, Central carbon metabolism in cancer
    Gene Ensembl ENSECAG00000006213, ENSMUSG00000006494, ENSCAFG00845028798, ENSG00000152256, ENSBTAG00000016836, ENSMMUG00000022553
    Target Classification Kinase, Tumor-associated antigen (TAA)


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