Human pak1/alpha-PAK/IDDMSSD ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001128620.1)

Cat. No.: pGMPC000263
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human pak1/alpha-PAK/IDDMSSD Non-Viral expression plasmid (overexpression vector) for mouse pak1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000263
Gene Name pak1
Accession Number NM_001128620.1
Gene ID 5058
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1662 bp
Gene Alias alpha-PAK,IDDMSSD,p65-PAK,PAKalpha
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag HA (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGTCAAATAACGGCCTAGACATTCAAGACAAACCCCCAGCCCCTCCGATGAGAAATACCAGCACTATGATTGGAGCCGGCAGCAAAGATGCTGGAACCCTAAACCATGGTTCTAAACCTCTGCCTCCAAACCCAGAGGAGAAGAAAAAGAAGGACCGATTTTACCGATCCATTTTACCTGGAGATAAAACAAATAAAAAGAAAGAGAAAGAGCGGCCAGAGATTTCTCTCCCTTCAGATTTTGAACACACAATTCATGTCGGTTTTGATGCTGTCACAGGGGAGTTTACGGGAATGCCAGAGCAGTGGGCCCGCTTGCTTCAGACATCAAATATCACTAAGTCGGAGCAGAAGAAAAACCCGCAGGCTGTTCTGGATGTGTTGGAGTTTTACAACTCGAAGAAGACATCCAACAGCCAGAAATACATGAGCTTTACAGATAAGTCAGCTGAGGATTACAATTCTTCTAATGCCTTGAATGTGAAGGCTGTGTCTGAGACTCCTGCAGTGCCACCAGTTTCAGAAGATGAGGATGATGATGATGATGATGCTACCCCACCACCAGTGATTGCTCCACGCCCAGAGCACACAAAATCTGTATACACACGGTCTGTGATTGAACCACTTCCTGTCACTCCAACTCGGGACGTGGCTACATCTCCCATTTCACCTACTGAAAATAACACCACTCCACCAGATGCTTTGACCCGGAATACTGAGAAGCAGAAGAAGAAGCCTAAAATGTCTGATGAGGAGATCTTGGAGAAATTACGAAGCATAGTGAGTGTGGGCGATCCTAAGAAGAAATATACACGGTTTGAGAAGATTGGACAAGGTGCTTCAGGCACCGTGTACACAGCAATGGATGTGGCCACAGGACAGGAGGTGGCCATTAAGCAGATGAATCTTCAGCAGCAGCCCAAGAAAGAGCTGATTATTAATGAGATCCTGGTCATGAGGGAAAACAAGAACCCAAACATTGTGAATTACTTGGACAGTTACCTCGTGGGAGATGAGCTGTGGGTTGTTATGGAATACTTGGCTGGAGGCTCCTTGACAGATGTGGTGACAGAAACTTGCATGGATGAAGGCCAAATTGCAGCTGTGTGCCGTGAGTGTCTGCAGGCTCTGGAGTTCTTGCATTCGAACCAGGTCATTCACAGAGACATCAAGAGTGACAATATTCTGTTGGGAATGGATGGCTCTGTCAAGCTAACTGACTTTGGATTCTGTGCACAGATAACCCCAGAGCAGAGCAAACGGAGCACCATGGTAGGAACCCCATACTGGATGGCACCAGAGGTTGTGACACGAAAGGCCTATGGGCCCAAGGTTGACATCTGGTCCCTGGGCATCATGGCCATCGAAATGATTGAAGGGGAGCCTCCATACCTCAATGAAAACCCTCTGAGAGCCTTGTACCTCATTGCCACCAATGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAA
ORF Protein Sequence MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRKLRFQVFSNFSMIAASIPEDCQAPLQPHSTDCCS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T37961-Ab Anti-PAK1/ PAKalpha monoclonal antibody
    Target Antigen GM-Tg-g-T37961-Ag PAK1 VLP (virus-like particle)
    ORF Viral Vector pGMLP005538 Human PAK1 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-062 Human PAK1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-202 Human PAK1 Adenovirus plasmid
    ORF Viral Vector pGMPC000262 Human PAK1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000263 Human pak1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005538 Human PAK1 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-062 Human PAK1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-202 Human PAK1 Adenovirus particle


    Target information

    Target ID GM-T37961
    Target Name PAK1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5058
    Gene ID 100063217 (Equus caballus), 101087171 (Felis catus), 18479 (Mus musculus), 29431 (Rattus norvegicus)
    5058 (Homo sapiens), 533729 (Bos taurus), 607885 (Canis lupus familiaris), 698585 (Macaca mulatta)
    Gene Symbols & Synonyms PAK1,Pak1,Paka,PAK-1,IDDMSSD,p65-PAK,PAKalpha,alpha-PAK
    Target Alternative Names Alpha-PAK,IDDMSSD,PAK-1,PAK1,PAKalpha,Pak1,Paka,Serine/threonine-protein kinase PAK 1,alpha-PAK,p21-activated kinase 1 (PAK-1),p65-PAK
    Uniprot Accession O88643,P35465,Q08E52,Q13153
    Additional SwissProt Accessions: O88643,P35465,Q13153,Q08E52
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Axon guidance, Focal adhesion, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Proteoglycans in cancer, Renal cell carcinoma
    Gene Ensembl ENSECAG00000017840, ENSMUSG00000030774, ENSG00000149269, ENSBTAG00000010191, ENSCAFG00845009162, ENSMMUG00000001387
    Target Classification Kinase, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.