Human TNFSF10/Apo-2L/APO2L ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_003810.3)

Cat. No.: pGMPC000026
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TNFSF10/Apo-2L/APO2L Non-Viral expression plasmid (overexpression vector) for mouse TNFSF10 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000026
Gene Name TNFSF10
Accession Number NM_003810.3
Gene ID 8743
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 846 bp
Gene Alias Apo-2L,APO2L,CD253,TL2,TNLG6A,TRAIL
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTATGATGGAGGTCCAGGGGGGACCCAGCCTGGGACAGACCTGCGTGCTGATCGTGATCTTCACAGTGCTCCTGCAGTCTCTCTGTGTGGCTGTAACTTACGTGTACTTTACCAACGAGCTGAAGCAGATGCAGGACAAGTACTCCAAAAGTGGCATTGCTTGTTTCTTAAAAGAAGATGACAGTTATTGGGACCCCAATGACGAAGAGAGTATGAACAGCCCCTGCTGGCAAGTCAAGTGGCAACTCCGTCAGCTCGTTAGAAAGATGATTTTGAGAACCTCTGAGGAAACCATTTCTACAGTTCAAGAAAAGCAACAAAATATTTCTCCCCTAGTGAGAGAAAGAGGTCCTCAGAGAGTAGCAGCTCACATAACTGGGACCAGAGGAAGAAGCAACACATTGTCTTCTCCAAACTCCAAGAATGAAAAGGCTCTGGGCCGCAAAATAAACTCCTGGGAATCATCAAGGAGTGGGCATTCATTCCTGAGCAACTTGCACTTGAGGAATGGTGAACTGGTCATCCATGAAAAAGGGTTTTACTACATCTATTCCCAAACATACTTTCGATTTCAGGAGGAAATAAAAGAAAACACAAAGAACGACAAACAAATGGTCCAATATATTTACAAATACACAAGTTATCCTGACCCTATATTGTTGATGAAAAGTGCTAGAAATAGTTGTTGGTCTAAAGATGCAGAATATGGACTCTATTCCATCTATCAAGGGGGAATATTTGAGCTTAAGGAAAATGACAGAATTTTTGTTTCTGTAACAAATGAGCACTTGATAGACATGGACCATGAAGCCAGTTTTTTTGGGGCCTTTTTAGTTGGCTAA
ORF Protein Sequence MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T46084-Ab Anti-TNF10/ TNFSF10/ APO2L functional antibody
    Target Antigen GM-Tg-g-T46084-Ag TNFSF10 protein
    Cytokine cks-Tg-g-GM-T46084 tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10) protein & antibody
    ORF Viral Vector pGMPC000026 Human TNFSF10 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000692 Human TNFSF10 Mammalian (Non-Viral Vector) plasmid


    Target information

    Target ID GM-T46084
    Target Name TRAIL/CD253/TNFSF10
    Gene Group Identifier
    （Target Gene ID in Homo species)         		8743
    Gene ID 100064377 (Equus caballus), 100174780 (Canis lupus familiaris), 100174789 (Felis catus), 22035 (Mus musculus)
    246775 (Rattus norvegicus), 507215 (Bos taurus), 694451 (Macaca mulatta), 8743 (Homo sapiens)
    Gene Symbols & Synonyms TNFSF10,Tnfsf10,TNLG6A,TRAIL,TL2,Ly81,Trail,APO-2L,Tnlg6a,A330042I21Rik,APO2L,CD253,TANCR,Apo-2L
    Target Alternative Names A330042I21Rik,APO-2L,APO2L,Apo-2 ligand (Apo-2L),Apo-2L,CD253,Ly81,TANCR,TL2,TNF-related apoptosis-inducing ligand (Protein TRAIL),TNFSF10,TNLG6A,TRAIL,Tnfsf10,Tnlg6a,Trail,Tumor necrosis factor ligand superfamily member 10
    Uniprot Accession P50591,P50592
    Additional SwissProt Accessions: P50592,P50591
    Uniprot Entry Name
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease cancer, Prostate Cancer
    Disease from KEGG Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, FoxO signaling pathway, Apoptosis, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Influenza A, Lipid and atherosclerosis
    Gene Ensembl ENSECAG00000019391, ENSCAFG00845025786, ENSMUSG00000039304, ENSBTAG00000018994, ENSMMUG00000019302, ENSG00000121858
    Target Classification Checkpoint-Immuno Oncology


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