Human SIRPA/BIT/CD172A ORF/cDNA clone-Lentivirus plasmid (NM_001330728)

Cat. No.: pGMLV002135
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SIRPA/BIT/CD172A Lentiviral expression plasmid for SIRPA lentivirus packaging, SIRPA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV002135
Gene Name SIRPA
Accession Number NM_001330728
Gene ID 140885
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1527 bp
Gene Alias BIT,CD172A,MFR,MYD-1,P84,PTPNS1,SHPS1,SIRP
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGCCCGCCGGCCCGGCCCCCGGCCGCCTCGGGCCGCTGCTCTGCCTGCTGCTCGCCGCGTCCTGCGCCTGGTCAGGAGTGGCGGGTGAGGAGGAGCTGCAGGTGATTCAGCCTGACAAGTCCGTGTTGGTTGCAGCTGGAGAGACAGCCACTCTGCGCTGCACTGCGACCTCTCTGATCCCTGTGGGGCCCATCCAGTGGTTCAGAGGAGCTGGACCAGGCCGGGAATTAATCTACAATCAAAAAGAAGGCCACTTCCCCCGGGTAACAACTGTTTCAGACCTCACAAAGAGAAACAACATGGACTTTTCCATCCGCATCGGTAACATCACCCCAGCAGATGCCGGCACCTACTACTGTGTGAAGTTCCGGAAAGGGAGCCCCGATGACGTGGAGTTTAAGTCTGGAGCAGGCACTGAGCTGTCTGTGCGCGCCAAACCCTCTGCCCCCGTGGTATCGGGCCCTGCGGCGAGGGCCACACCTCAGCACACAGTGAGCTTCACCTGCGAGTCCCACGGCTTCTCACCCAGAGACATCACCCTGAAATGGTTCAAAAATGGGAATGAGCTCTCAGACTTCCAGACCAACGTGGACCCCGTAGGAGAGAGCGTGTCCTACAGCATCCACAGCACAGCCAAGGTGGTGCTGACCCGCGAGGACGTTCACTCTCAAGTCATCTGCGAGGTGGCCCACGTCACCTTGCAGGGGGACCCTCTTCGTGGGACTGCCAACTTGTCTGAGACCATCCGAGTTCCACCCACCTTGGAGGTTACTCAACAGCCCGTGAGGGCAGAGAACCAGGTGAATGTCACCTGCCAGGTGAGGAAGTTCTACCCCCAGAGACTACAGCTGACCTGGTTGGAGAATGGAAACGTGTCCCGGACAGAAACGGCCTCAACCGTTACAGAGAACAAGGATGGTACCTACAACTGGATGAGCTGGCTCCTGGTGAATGTATCTGCCCACAGGGATGATGTGAAGCTCACCTGCCAGGTGGAGCATGACGGGCAGCCAGCGGTCAGCAAAAGCCATGACCTGAAGGTCTCAGCCCACCCGAAGGAGCAGGGCTCAAATACCGCCGCTGAGAACACTGGATCTAATGAACGGAACATCTATATTGTGGTGGGTGTGGTGTGCACCTTGCTGGTGGCCCTACTGATGGCGGCCCTCTACCTCGTCCGAATCAGACAGAAGAAAGCCCAGGGCTCCACTTCTTCTACAAGGTTGCATGAGCCCGAGAAGAATGCCAGAGAAATAACACAGGTACAGTCCTTGGACACAAATGATATCACATATGCAGACCTGAACCTGCCCAAGGGGAAGAAGCCTGCTCCCCAGGCTGCGGAGCCCAACAACCACACGGAGTATGCCAGCATTCAGACCAGCCCGCAGCCCGCGTCGGAGGACACCCTCACCTATGCTGACCTGGACATGGTCCACCTCAACCGGACCCCCAAGCAGCCGGCCCCCAAGCCTGAGCCGTCCTTCTCAGAGTACGCCAGCGTCCAGGTCCCGAGGAAGTGA
ORF Protein Sequence MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQVQSLDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T46789-Ab Anti-SHPS1/ SIRPA/ BIT monoclonal antibody
    Target Antigen GM-Tg-g-T46789-Ag SIRPA VLP (virus-like particle)
    ORF Viral Vector pGMLV002135 Human SIRPA Lentivirus plasmid
    ORF Viral Vector vGMLV002135 Human SIRPA Lentivirus particle


    Target information

    Target ID GM-T46789
    Target Name SIRP Alpha/CD172a/SIRPA
    Gene Group Identifier
    （Target Gene ID in Homo species)         		140885
    Gene ID 100067339 (Equus caballus), 101084787 (Felis catus), 140885 (Homo sapiens), 19261 (Mus musculus)
    25528 (Rattus norvegicus), 327666 (Bos taurus), 609452 (Canis lupus familiaris), 717811 (Macaca mulatta)
    Gene Symbols & Synonyms SIRPA,Sirpa,MYD-1,BIT,MFR,P84,SIRP,SHPS1,CD172A,PTPNS1,Bit,SHP-1,CD172a,Ptpns1,SHPS-1,Idd13.2
    Target Alternative Names BIT,Bit,Brain Ig-like molecule with tyrosine-based activation motifs (Bit),CD172 antigen-like family member A,CD172A,CD172a,Idd13.2,Inhibitory receptor SHPS-1,MFR,MYD-1,Macrophage fusion receptor,MyD-1 antigen,P84,PTPNS1,Ptpns1,SHP substrate 1,SHP-1,SHPS-1,SHPS1,SIRP,SIRP Alpha,SIRPA,Signal-regulatory protein alpha-1 (Sirp-alpha-1),Signal-regulatory protein alpha-2 (Sirp-alpha-2),Signal-regulatory protein alpha-3 (Sirp-alpha-3),Sirpa,Tyrosine-protein phosphatase non-receptor type substrate 1,p84
    Uniprot Accession O46631,P78324,P97710,P97797
    Additional SwissProt Accessions: P78324,P97797,P97710,O46631
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease
    Disease from KEGG Osteoclast differentiation
    Gene Ensembl ENSECAG00000035431, ENSG00000198053, ENSMUSG00000037902, ENSBTAG00000007213, ENSCAFG00845017411, ENSMMUG00000018474
    Target Classification Checkpoint-Immuno Oncology


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.