Human FOXO1/FKH1/FKHR ORF/cDNA clone-Lentivirus plasmid (NM_002015)

Cat. No.: pGMLV002023
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human FOXO1/FKH1/FKHR Lentiviral expression plasmid for FOXO1 lentivirus packaging, FOXO1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV002023
Gene Name FOXO1
Accession Number NM_002015
Gene ID 2308
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1968 bp
Gene Alias FKH1,FKHR,FOXO1A
Fluorescent Reporter mCherry
Mammalian Cell Selection Blasticidin (BSD)
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCGAGGCGCCTCAGGTGGTGGAGATCGACCCGGACTTCGAGCCGCTGCCCCGGCCGCGCTCGTGCACCTGGCCGCTGCCCAGGCCGGAGTTTAGCCAGTCCAACTCGGCCACCTCCAGCCCGGCGCCGTCGGGCAGCGCGGCTGCCAACCCCGACGCCGCGGCGGGCCTGCCCTCGGCCTCGGCTGCCGCTGTCAGCGCCGACTTCATGAGCAACCTGAGCTTGCTGGAGGAGAGCGAGGACTTCCCGCAGGCGCCCGGCTCCGTGGCGGCGGCGGTGGCGGCGGCGGCCGCCGCGGCCGCCACCGGGGGGCTGTGCGGGGACTTCCAGGGCCCGGAGGCGGGCTGCCTGCACCCAGCGCCACCGCAGCCCCCGCCGCCCGGGCCGCTGTCGCAGCACCCGCCGGTGCCCCCCGCCGCCGCTGGGCCGCTCGCGGGGCAGCCGCGCAAGAGCAGCTCGTCCCGCCGCAACGCGTGGGGCAACCTGTCCTACGCCGACCTCATCACCAAGGCCATCGAGAGCTCGGCGGAGAAGCGGCTCACGCTGTCGCAGATCTACGAGTGGATGGTCAAGAGCGTGCCCTACTTCAAGGATAAGGGTGACAGCAACAGCTCGGCGGGCTGGAAGAATTCAATTCGTCATAATCTGTCCCTACACAGCAAGTTCATTCGTGTGCAGAATGAAGGAACTGGAAAAAGTTCTTGGTGGATGCTCAATCCAGAGGGTGGCAAGAGCGGGAAATCTCCTAGGAGAAGAGCTGCATCCATGGACAACAACAGTAAATTTGCTAAGAGCCGAAGCCGAGCTGCCAAGAAGAAAGCATCTCTCCAGTCTGGCCAGGAGGGTGCTGGGGACAGCCCTGGATCACAGTTTTCCAAATGGCCTGCAAGCCCTGGCTCTCACAGCAATGATGACTTTGATAACTGGAGTACATTTCGCCCTCGAACTAGCTCAAATGCTAGTACTATTAGTGGGAGACTCTCACCCATTATGACCGAACAGGATGATCTTGGAGAAGGGGATGTGCATTCTATGGTGTACCCGCCATCTGCCGCAAAGATGGCCTCTACTTTACCCAGTCTGTCTGAGATAAGCAATCCCGAAAACATGGAAAATCTTTTGGATAATCTCAACCTTCTCTCATCACCAACATCATTAACTGTTTCGACCCAGTCCTCACCTGGCACCATGATGCAGCAGACGCCGTGCTACTCGTTTGCGCCACCAAACACCAGTTTGAATTCACCCAGCCCAAACTACCAAAAATATACATATGGCCAATCCAGCATGAGCCCTTTGCCCCAGATGCCTATACAAACACTTCAGGACAATAAGTCGAGTTATGGAGGTATGAGTCAGTATAACTGTGCGCCTGGACTCTTGAAGGAGTTGCTGACTTCTGACTCTCCTCCCCATAATGACATTATGACACCAGTTGATCCTGGGGTAGCCCAGCCCAACAGCCGGGTTCTGGGCCAGAACGTCATGATGGGCCCTAATTCGGTCATGTCAACCTATGGCAGCCAGGCATCTCATAACAAAATGATGAATCCCAGCTCCCATACCCACCCTGGACATGCTCAGCAGACATCTGCAGTTAACGGGCGTCCCCTGCCCCACACGGTAAGCACCATGCCCCACACCTCGGGTATGAACCGCCTGACCCAAGTGAAGACACCTGTACAAGTGCCTCTGCCCCACCCCATGCAGATGAGTGCCCTGGGGGGCTACTCCTCCGTGAGCAGCTGCAATGGCTATGGCAGAATGGGCCTTCTCCACCAGGAGAAGCTCCCAAGTGACTTGGATGGCATGTTCATTGAGCGCTTAGACTGTGACATGGAATCCATCATTCGGAATGACCTCATGGATGGAGATACATTGGATTTTAACTTTGACAATGTGTTGCCCAACCAAAGCTTCCCACACAGTGTCAAGACAACGACACATAGCTGGGTGTCAGGCTGA
ORF Protein Sequence MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPVDPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T72850-Ab Anti-FOXO1 monoclonal antibody
    Target Antigen GM-Tg-g-T72850-Ag FOXO1 protein
    ORF Viral Vector pGMLV000310 Human FOXO1 Lentivirus plasmid
    ORF Viral Vector pGMLV001668 Human FOXO1 Lentivirus plasmid
    ORF Viral Vector pGMLV002023 Human FOXO1 Lentivirus plasmid
    ORF Viral Vector pGMLV002427 Human FOXO1 Lentivirus plasmid
    ORF Viral Vector pGMAD000137 Human FOXO1 Adenovirus plasmid
    ORF Viral Vector pGMAD000525 Human FOXO1 Adenovirus plasmid
    ORF Viral Vector pGMAD000764 Human FOXO1 Adenovirus plasmid
    ORF Viral Vector pGMPC000687 Human FOXO1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000310 Human FOXO1 Lentivirus particle
    ORF Viral Vector vGMLV001668 Human FOXO1 Lentivirus particle
    ORF Viral Vector vGMLV002023 Human FOXO1 Lentivirus particle
    ORF Viral Vector vGMLV002427 Human FOXO1 Lentivirus particle
    ORF Viral Vector vGMAD000137 Human FOXO1 Adenovirus particle
    ORF Viral Vector vGMAD000525 Human FOXO1 Adenovirus particle
    ORF Viral Vector vGMAD000764 Human FOXO1 Adenovirus particle


    Target information

    Target ID GM-T72850
    Target Name FOXO1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		2308
    Gene ID 100050481 (Equus caballus), 101096628 (Felis catus), 2308 (Homo sapiens), 477295 (Canis lupus familiaris)
    506618 (Bos taurus), 56458 (Mus musculus), 700030 (Macaca mulatta), 84482 (Rattus norvegicus)
    Gene Symbols & Synonyms FOXO1,Foxo1,FKH1,FKHR,FOXO1A,Afxh,Fkhr1,Foxo1a,Fkhr
    Target Alternative Names Afxh,FKH1,FKHR,FOXO1,FOXO1A,Fkhr,Fkhr1,Forkhead box protein O1,Forkhead box protein O1A,Forkhead in rhabdomyosarcoma,Foxo1,Foxo1a
    Uniprot Accession E1BPQ1,G3V7R4,Q12778,Q9R1E0
    Additional SwissProt Accessions: Q12778,E1BPQ1,Q9R1E0,G3V7R4
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG FoxO signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Thyroid hormone signaling pathway, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Human papillomavirus infection, Pathways in cancer, Prostate cancer
    Gene Ensembl ENSECAG00000002212, ENSG00000150907, ENSCAFG00845024108, ENSBTAG00000044105, ENSMUSG00000044167, ENSMMUG00000030780
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.