Human SIGIRR/IL-1R8/TIR8 ORF/cDNA clone-Lentivirus plasmid (NM_001135053.1)

Cat. No.: pGMLV000704
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SIGIRR/IL-1R8/TIR8 Lentiviral expression plasmid for SIGIRR lentivirus packaging, SIGIRR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000704
Gene Name SIGIRR
Accession Number NM_001135053.1
Gene ID 59307
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1233 bp
Gene Alias IL-1R8,TIR8
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCAGGTGTCTGTGATAGGGCCCCTGACTTCCTCTCCCCGTCTGAAGACCAGGTGCTGAGGCCTGCCTTGGGCAGCTCAGTGGCTCTGAACTGCACGGCTTGGGTAGTCTCTGGGCCCCACTGCTCCCTGCCTTCAGTCCAGTGGCTGAAAGACGGGCTTCCATTGGGAATTGGGGGCCACTACAGCCTCCACGAGTACTCCTGGGTCAAGGCCAACCTGTCAGAGGTGCTTGTGTCCAGTGTCCTGGGGGTCAACGTGACCAGCACTGAAGTCTATGGGGCCTTCACCTGCTCCATCCAGAACATCAGCTTCTCCTCCTTCACTCTTCAGAGAGCTGGCCCTACAAGCCACGTGGCTGCGGTGCTGGCCTCCCTCCTGGTCCTGCTGGCCCTGCTGCTGGCCGCCCTGCTCTATGTCAAGTGCCGTCTCAACGTGCTGCTCTGGTACCAGGACGCGTATGGGGAGGTGGAGATAAACGACGGGAAGCTCTACGACGCCTACGTCTCCTACAGCGACTGCCCCGAGGACCGCAAGTTCGTGAACTTCATCCTAAAGCCGCAGCTGGAGCGGCGTCGGGGCTACAAGCTCTTCCTGGACGACCGCGACCTCCTGCCGCGCGCTGAGCCCTCCGCCGACCTCTTGGTGAACCTGAGCCGCTGCCGACGCCTCATCGTGGTGCTTTCGGACGCCTTCCTGAGCCGGGCCTGGTGCAGCCACAGCTTCCGGGAGGGCCTGTGCCGGCTGCTGGAGCTCACCCGCAGACCCATCTTCATCACCTTCGAGGGCCAGAGGCGCGACCCCGCGCACCCGGCGCTCCGCCTGCTGCGCCAGCACCGCCACCTGGTGACCTTGCTGCTCTGGAGGCCCGGCTCCGTGACTCCTTCCTCCGATTTTTGGAAAGAAGTGCAGCTGGCGCTGCCGCGGAAGGTGCAGTACAGGCCTGTGGAAGGAGACCCCCAGACGCAGCTGCAGGACGACAAGGACCCCATGCTGATTCTTCGAGGCCGAGTCCCTGAGGGCCGGGCCCTGGACTCAGAGGTGGACCCGGACCCTGAGGGCGACCTGGGTGTCCGGGGGCCTGTCTTTGGAGAGCCATCAGCTCCACCGCACACCAGTGGGGTCTCGCTGGGAGAGAGCCGGAGCAGCGAAGTGGACGTCTCGGATCTCGGCTCGCGAAACTACAGTGCCCGCACAGACTTCTACTGCCTGGTGTCCAAGGATGATATGTAG
ORF Protein Sequence MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1516-Ab Anti-SIGIR/ SIGIRR/ IL-1R8 monoclonal antibody
    Target Antigen GM-Tg-g-MP1516-Ag SIGIRR VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-MP1516 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR) protein & antibody
    ORF Viral Vector pGMLV000704 Human SIGIRR Lentivirus plasmid
    ORF Viral Vector pGMAP000069 Human SIGIRR Adenovirus plasmid
    ORF Viral Vector vGMLV000704 Human SIGIRR Lentivirus particle
    ORF Viral Vector vGMAP000069 Human SIGIRR Adenovirus particle


    Target information

    Target ID GM-MP1516
    Target Name SIGIRR
    Gene Group Identifier
    （Target Gene ID in Homo species)         		59307
    Gene ID 100054544 (Equus caballus), 100686933 (Canis lupus familiaris), 101100416 (Felis catus), 24058 (Mus musculus)
    309106 (Rattus norvegicus), 531801 (Bos taurus), 59307 (Homo sapiens)
    Gene Symbols & Synonyms SIGIRR,Sigirr,TIR8,RGD1306732,IL-1R8
    Target Alternative Names IL-1R8,RGD1306732,SIGIRR,Sigirr,Single Ig IL-1-related receptor,Single Ig IL-1R-related molecule,Single immunoglobulin domain-containing IL1R-related protein,TIR8,Toll/interleukin-1 receptor 8 (TIR8)
    Uniprot Accession Q4V892,Q6IA17,Q9JLZ8
    Additional SwissProt Accessions: Q9JLZ8,Q4V892,Q6IA17
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Cytokine Target
    Disease
    Disease from KEGG
    Gene Ensembl ENSECAG00000022225, ENSCAFG00845029342, ENSMUSG00000025494, ENSBTAG00000011149, ENSG00000185187
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.