Human MDM2/ACTFS/hdm2 ORF/cDNA clone-Lentivirus plasmid (NM_002392.5)

Cat. No.: pGMLV000680
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human MDM2/ACTFS/hdm2 Lentiviral expression plasmid for MDM2 lentivirus packaging, MDM2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000680
Gene Name MDM2
Accession Number NM_002392.5
Gene ID 4193
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1494 bp
Gene Alias ACTFS,hdm2,HDMX
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAG
ORF Protein Sequence MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T00176-Ab Anti-MDM2 monoclonal antibody
    Target Antigen GM-Tg-g-T00176-Ag MDM2 protein
    ORF Viral Vector pGMLP005735 Human MDM2 Lentivirus plasmid
    ORF Viral Vector pGMLV000680 Human MDM2 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-001 Human MDM2 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-141 Human MDM2 Adenovirus plasmid
    ORF Viral Vector pGMPC001312 Human MDM2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004812 Human MDM2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004828 Human MDM2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004926 Human MDM2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005735 Human MDM2 Lentivirus particle
    ORF Viral Vector vGMLV000680 Human MDM2 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-001 Human MDM2 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-141 Human MDM2 Adenovirus particle


    Target information

    Target ID GM-T00176
    Target Name MDM2/HDM2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		4193
    Gene ID 100052084 (Equus caballus), 17246 (Mus musculus), 314856 (Rattus norvegicus), 403693 (Canis lupus familiaris)
    4193 (Homo sapiens), 493939 (Felis catus), 540378 (Bos taurus), 718284 (Macaca mulatta)
    Gene Symbols & Synonyms MDM2,Mdm2,edm2,Mdm-2,1700007J15Rik,HDMX,LSKB,hdm2,ACTFS
    Target Alternative Names 1700007J15Rik,ACTFS,Double minute 2 protein (Hdm2),E3 ubiquitin-protein ligase Mdm2,HDM2,HDMX,LSKB,MDM2,Mdm-2,Mdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,edm2,hdm2,p53-binding protein Mdm2
    Uniprot Accession P23804,P56950,P56951,Q00987,Q7YRZ8
    Additional SwissProt Accessions: P56951,P23804,P56950,Q00987,Q7YRZ8
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer, Breast Cancer
    Disease from KEGG Endocrine resistance, FoxO signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, C-type lectin receptor signaling pathway, Thyroid hormone signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Proteoglycans in cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia
    Gene Ensembl ENSECAG00000013604, ENSMUSG00000020184, ENSCAFG00845016387, ENSG00000135679, ENSBTAG00000010422, ENSMMUG00000055447
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.