Human PRKAA1/AMPK/AMPKa1 ORF/cDNA clone-Lentivirus plasmid (NM_006251.5)

Cat. No.: pGMLV000515
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PRKAA1/AMPK/AMPKa1 Lentiviral expression plasmid for PRKAA1 lentivirus packaging, PRKAA1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000515
Gene Name PRKAA1
Accession Number NM_006251.5
Gene ID 5562
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1680 bp
Gene Alias AMPK,AMPKa1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGCAGACTCAGTTCCTGGAGAAAGATGGCGACAGCCGAGAAGCAGAAACACGACGGGCGGGTGAAGATCGGCCACTACATTCTGGGTGACACGCTGGGGGTCGGCACCTTCGGCAAAGTGAAGGTTGGCAAACATGAATTGACTGGGCATAAAGTAGCTGTGAAGATACTCAATCGACAGAAGATTCGGAGCCTTGATGTGGTAGGAAAAATCCGCAGAGAAATTCAGAACCTCAAGCTTTTCAGGCATCCTCATATAATTAAACTGTACCAGGTCATCAGTACACCATCTGATATTTTCATGGTGATGGAATATGTCTCAGGAGGAGAGCTATTTGATTATATCTGTAAGAATGGAAGGCTGGATGAAAAAGAAAGTCGGCGTCTGTTCCAACAGATCCTTTCTGGTGTGGATTATTGTCACAGGCATATGGTGGTCCATAGAGATTTGAAACCTGAAAATGTCCTGCTTGATGCACACATGAATGCAAAGATAGCTGATTTTGGTCTTTCAAACATGATGTCAGATGGTGAATTTTTAAGAACAAGTTGTGGCTCACCCAACTATGCTGCACCAGAAGTAATTTCAGGAAGATTGTATGCAGGCCCAGAGGTAGATATATGGAGCAGTGGGGTTATTCTCTATGCTTTATTATGTGGAACCCTTCCATTTGATGATGACCATGTGCCAACTCTTTTTAAGAAGATATGTGATGGGATCTTCTATACCCCTCAATATTTAAATCCTTCTGTGATTAGCCTTTTGAAACATATGCTGCAGGTGGATCCCATGAAGAGGGCCACAATCAAAGATATCAGGGAACATGAATGGTTTAAACAGGACCTTCCAAAATATCTCTTTCCTGAGGATCCATCATATAGTTCAACCATGATTGATGATGAAGCCTTAAAAGAAGTATGTGAAAAGTTTGAGTGCTCAGAAGAGGAAGTTCTCAGCTGTCTTTACAACAGAAATCACCAGGATCCTTTGGCAGTTGCCTACCATCTCATAATAGATAACAGGAGAATAATGAATGAAGCCAAAGATTTCTATTTGGCGACAAGCCCACCTGATTCTTTTCTTGATGATCATCACCTGACTCGGCCCCATCCTGAAAGAGTACCATTCTTGGTTGCTGAAACACCAAGGGCACGCCATACCCTTGATGAATTAAATCCACAGAAATCCAAACACCAAGGTGTAAGGAAAGCAAAATGGCATTTAGGAATTAGAAGTCAAAGTCGACCAAATGATATTATGGCAGAAGTATGTAGAGCAATCAAACAATTGGATTATGAATGGAAGGTTGTAAACCCATATTATTTGCGTGTACGAAGGAAGAATCCTGTGACAAGCACTTACTCCAAAATGAGTCTACAGTTATACCAAGTGGATAGTAGAACTTATCTACTGGATTTCCGTAGTATTGATGATGAAATTACAGAAGCCAAATCAGGGACTGCTACTCCACAGAGATCGGGATCAGTTAGCAACTATCGATCTTGCCAAAGGAGTGATTCAGATGCTGAGGCTCAAGGAAAATCCTCAGAAGTTTCTCTTACCTCATCTGTGACCTCACTTGACTCTTCTCCTGTTGACCTAACTCCAAGACCTGGAAGTCACACAATAGAATTTTTTGAGATGTGTGCAAATCTAATTAAAATTCTTGCACAATAA
ORF Protein Sequence MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-TA017-Ab Anti-PRKAA1 monoclonal antibody
    Target Antigen GM-Tg-g-TA017-Ag PRKAA1 protein
    ORF Viral Vector pGMLP005602 Human PRKAA1 Lentivirus plasmid
    ORF Viral Vector pGMLV000515 Human PRKAA1 Lentivirus plasmid
    ORF Viral Vector pGMLV000577 Human PRKAA1 Lentivirus plasmid
    ORF Viral Vector pGMLV001150 Human PRKAA1 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-132 Human PRKAA1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-272 Human PRKAA1 Adenovirus plasmid
    ORF Viral Vector pGMPC000051 Human PRKAA1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005602 Human PRKAA1 Lentivirus particle
    ORF Viral Vector vGMLV000515 Human PRKAA1 Lentivirus particle
    ORF Viral Vector vGMLV000577 Human PRKAA1 Lentivirus particle
    ORF Viral Vector vGMLV001150 Human PRKAA1 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-132 Human PRKAA1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-272 Human PRKAA1 Adenovirus particle


    Target information

    Target ID GM-TA017
    Target Name AMPK Alpha 1/AMPK Alpha/PRKAA1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5562
    Gene ID 100009710 (Equus caballus), 101095885 (Felis catus), 105787 (Mus musculus), 479351 (Canis lupus familiaris)
    540404 (Bos taurus), 5562 (Homo sapiens), 65248 (Rattus norvegicus), 695558 (Macaca mulatta)
    Gene Symbols & Synonyms PRKAA1,Prkaa1,AMPKalpha1,C130083N04Rik,AMPK,AMPKa1,AMPK alpha 1
    Target Alternative Names 5'-AMP-activated protein kinase catalytic subunit alpha-1,AMPK,AMPK Alpha,AMPK Alpha 1,AMPK alpha 1,AMPK subunit alpha-1,AMPKa1,AMPKalpha1,Acetyl-CoA carboxylase kinase (ACACA kinase),C130083N04Rik,Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase),PRKAA1,Prkaa1,Tau-protein kinase PRKAA1
    Uniprot Accession P54645,Q13131,Q5EG47
    Additional SwissProt Accessions: Q5EG47,Q13131,P54645
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG FoxO signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Tight junction, Adipocytokine signaling pathway, Oxytocin signaling pathway, Insulin resistance, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis
    Gene Ensembl ENSECAG00000022617, ENSMUSG00000050697, ENSCAFG00845002768, ENSBTAG00000000013, ENSG00000132356, ENSMMUG00000023806
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.