Human CASP3/CPP32/CPP32B ORF/cDNA clone-Lentivirus plasmid (NM_032991.2)

Cat. No.: pGMLP005817
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CASP3/CPP32/CPP32B Lentiviral expression plasmid for CASP3 lentivirus packaging, CASP3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005817
Gene Name CASP3
Accession Number NM_032991.2
Gene ID 836
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 834 bp
Gene Alias CPP32,CPP32B,SCA-1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGAACACTGAAAACTCAGTGGATTCAAAATCCATTAAAAATTTGGAACCAAAGATCATACATGGAAGCGAATCAATGGACTCTGGAATATCCCTGGACAACAGTTATAAAATGGATTATCCTGAGATGGGTTTATGTATAATAATTAATAATAAGAATTTTCATAAAAGCACTGGAATGACATCTCGGTCTGGTACAGATGTCGATGCAGCAAACCTCAGGGAAACATTCAGAAACTTGAAATATGAAGTCAGGAATAAAAATGATCTTACACGTGAAGAAATTGTGGAATTGATGCGTGATGTTTCTAAAGAAGATCACAGCAAAAGGAGCAGTTTTGTTTGTGTGCTTCTGAGCCATGGTGAAGAAGGAATAATTTTTGGAACAAATGGACCTGTTGACCTGAAAAAAATAACAAACTTTTTCAGAGGGGATCGTTGTAGAAGTCTAACTGGAAAACCCAAACTTTTCATTATTCAGGCCTGCCGTGGTACAGAACTGGACTGTGGCATTGAGACAGACAGTGGTGTTGATGATGACATGGCGTGTCATAAAATACCAGTGGAGGCCGACTTCTTGTATGCATACTCCACAGCACCTGGTTATTATTCTTGGCGAAATTCAAAGGATGGCTCCTGGTTCATCCAGTCGCTTTGTGCCATGCTGAAACAGTATGCCGACAAGCTTGAATTTATGCACATTCTTACCCGGGTTAACCGAAAGGTGGCAACAGAATTTGAGTCCTTTTCCTTTGACGCTACTTTTCATGCAAAGAAACAGATTCCATGTATTGTTTCCATGCTCACAAAAGAACTCTATTTTTATCACTAA
ORF Protein Sequence MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T57943-Ab Anti-CASP3 monoclonal antibody
    Target Antigen GM-Tg-g-T57943-Ag CASP3 protein
    ORF Viral Vector pGMLP005817 Human CASP3 Lentivirus plasmid
    ORF Viral Vector pGMAP000159 Human CASP3 Adenovirus plasmid
    ORF Viral Vector vGMLP005817 Human CASP3 Lentivirus particle
    ORF Viral Vector vGMAP000159 Human CASP3 Adenovirus particle


    Target information

    Target ID GM-T57943
    Target Name CASP3/Caspase 3/P17/P19/Cleaved Caspase 3
    Gene Group Identifier
    （Target Gene ID in Homo species)         		836
    Gene ID 100034083 (Equus caballus), 12367 (Mus musculus), 25402 (Rattus norvegicus), 403567 (Canis lupus familiaris)
    408016 (Bos taurus), 493932 (Felis catus), 694473 (Macaca mulatta), 836 (Homo sapiens)
    Gene Symbols & Synonyms CASP3,Casp3,CC3,AC-3,Lice,Yama,mldy,CPP32,SCA-1,CASP-3,CPP-32,Caspase-3,A830040C14Rik,CPP32-beta,CPP32B
    Target Alternative Names A830040C14Rik,AC-3,Apopain,CASP-3,CASP3,CC3,CPP-32,CPP32,CPP32-beta,CPP32B,Casp3,Caspase 3,Caspase-3,Cleaved Caspase 3,Cysteine protease CPP32 (CPP-32),Lice,P17,P19,Protein Yama,SCA-1,SREBP cleavage activity 1 (SCA-1),Yama,mldy
    Uniprot Accession P42574,P55213,P70677,Q08DY9,Q8MJU1,Q8MKI5
    Additional SwissProt Accessions: P70677,P55213,Q8MKI5,Q08DY9,Q8MJU1,P42574
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer, gastric carcinoma, gastric cancer
    Disease from KEGG MAPK signaling pathway, p53 signaling pathway, Apoptosis, Apoptosis - multiple species, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, TNF signaling pathway, Serotonergic synapse, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Pertussis, Legionellosis, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Small cell lung cancer, Viral myocarditis, Lipid and atherosclerosis
    Gene Ensembl ENSECAG00000022197, ENSMUSG00000031628, ENSCAFG00845015288, ENSBTAG00000015874, ENSMMUG00000012053, ENSG00000164305
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.