Human CHEK2/CDS1/CHK2 ORF/cDNA clone-Lentivirus plasmid (NM_007194.3)

Cat. No.: pGMLP005480
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CHEK2/CDS1/CHK2 Lentiviral expression plasmid for CHEK2 lentivirus packaging, CHEK2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005480
Gene Name CHEK2
Accession Number NM_007194.3
Gene ID 11200
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1632 bp
Gene Alias CDS1,CHK2,hCds1,HuCds1,LFS2,PP1425,RAD53
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCTCGGGAGTCGGATGTTGAGGCTCAGCAGTCTCATGGCAGCAGTGCCTGTTCACAGCCCCATGGCAGCGTTACCCAGTCCCAAGGCTCCTCCTCACAGTCCCAGGGCATATCCAGCTCCTCTACCAGCACGATGCCAAACTCCAGCCAGTCCTCTCACTCCAGCTCTGGGACACTGAGCTCCTTAGAGACAGTGTCCACTCAGGAACTCTATTCTATTCCTGAGGACCAAGAACCTGAGGACCAAGAACCTGAGGAGCCTACCCCTGCCCCCTGGGCTCGATTATGGGCCCTTCAGGATGGATTTGCCAATCTTGAATGTGTGAATGACAACTACTGGTTTGGGAGGGACAAAAGCTGTGAATATTGCTTTGATGAACCACTGCTGAAAAGAACAGATAAATACCGAACATACAGCAAGAAACACTTTCGGATTTTCAGGGAAGTGGGTCCTAAAAACTCTTACATTGCATACATAGAAGATCACAGTGGCAATGGAACCTTTGTAAATACAGAGCTTGTAGGGAAAGGAAAACGCCGTCCTTTGAATAACAATTCTGAAATTGCACTGTCACTAAGCAGAAATAAAGTTTTTGTCTTTTTTGATCTGACTGTAGATGATCAGTCAGTTTATCCTAAGGCATTAAGAGATGAATACATCATGTCAAAAACTCTTGGAAGTGGTGCCTGTGGAGAGGTAAAGCTGGCTTTCGAGAGGAAAACATGTAAGAAAGTAGCCATAAAGATCATCAGCAAAAGGAAGTTTGCTATTGGTTCAGCAAGAGAGGCAGACCCAGCTCTCAATGTTGAAACAGAAATAGAAATTTTGAAAAAGCTAAATCATCCTTGCATCATCAAGATTAAAAACTTTTTTGATGCAGAAGATTATTATATTGTTTTGGAATTGATGGAAGGGGGAGAGCTGTTTGACAAAGTGGTGGGGAATAAACGCCTGAAAGAAGCTACCTGCAAGCTCTATTTTTACCAGATGCTCTTGGCTGTGCAGTACCTTCATGAAAACGGTATTATACACCGTGACTTAAAGCCAGAGAATGTTTTACTGTCATCTCAAGAAGAGGACTGTCTTATAAAGATTACTGATTTTGGGCACTCCAAGATTTTGGGAGAGACCTCTCTCATGAGAACCTTATGTGGAACCCCCACCTACTTGGCGCCTGAAGTTCTTGTTTCTGTTGGGACTGCTGGGTATAACCGTGCTGTGGACTGCTGGAGTTTAGGAGTTATTCTTTTTATCTGCCTTAGTGGGTATCCACCTTTCTCTGAGCATAGGACTCAAGTGTCACTGAAGGATCAGATCACCAGTGGAAAATACAACTTCATTCCTGAAGTCTGGGCAGAAGTCTCAGAGAAAGCTCTGGACCTTGTCAAGAAGTTGTTGGTAGTGGATCCAAAGGCACGTTTTACGACAGAAGAAGCCTTAAGACACCCGTGGCTTCAGGATGAAGACATGAAGAGAAAGTTTCAAGATCTTCTGTCTGAGGAAAATGAATCCACAGCTCTACCCCAGGTTCTAGCCCAGCCTTCTACTAGTCGAAAGCGGCCCCGTGAAGGGGAAGCCGAGGGTGCCGAGACCACAAAGCGCCCAGCTGTGTGTGCTGCTGTGTTGTGA
ORF Protein Sequence MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0043-Ab Anti-RAD53 monoclonal antibody
    Target Antigen GM-Tg-g-IP0043-Ag RAD53/CHEK2 protein
    ORF Viral Vector pGMLP000677 Human CHEK2 Lentivirus plasmid
    ORF Viral Vector pGMLP005480 Human CHEK2 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-005 Human CHEK2 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-145 Human CHEK2 Adenovirus plasmid
    ORF Viral Vector pGMPC001827 Human CHEK2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000677 Human CHEK2 Lentivirus particle
    ORF Viral Vector vGMLP005480 Human CHEK2 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-005 Human CHEK2 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-145 Human CHEK2 Adenovirus particle


    Target information

    Target ID GM-IP0043
    Target Name CHEK2/RAD53
    Gene Group Identifier
    （Target Gene ID in Homo species)         		11200
    Gene ID 100059288 (Equus caballus), 101085665 (Felis catus), 11200 (Homo sapiens), 114212 (Rattus norvegicus)
    486338 (Canis lupus familiaris), 50883 (Mus musculus), 518897 (Bos taurus), 713668 (Macaca mulatta)
    Gene Symbols & Synonyms CHEK2,Chek2,CDS1,CHK2,LFS2,RAD53,TPDS4,hCds1,HuCds1,PP1425,Chk2,Rad53,Cds1,HUCDS1
    Target Alternative Names CDS1,CHEK2,CHK2,CHK2 checkpoint homolog,Cds1,Cds1 homolog (Hucds1,Checkpoint kinase 2,Chek2,Chk2,HUCDS1,HuCds1,LFS2,PP1425,RAD53,Rad53,Serine/threonine-protein kinase Chk2,TPDS4,hCds1,hCds1)
    Uniprot Accession O96017,Q9Z265
    Additional SwissProt Accessions: O96017,Q9Z265
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease cancer
    Disease from KEGG p53 signaling pathway, Cellular senescence, Human T-cell leukemia virus 1 infection
    Gene Ensembl ENSECAG00000004845, ENSG00000183765, ENSCAFG00845030072, ENSMUSG00000029521, ENSBTAG00000004956, ENSMMUG00000020486
    Target Classification Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.