Human ACVR1/ACTRI/ACVR1A ORF/cDNA clone-Lentivirus plasmid (NM_001105.4)

Cat. No.: pGMLP005182
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human ACVR1/ACTRI/ACVR1A Lentiviral expression plasmid for ACVR1 lentivirus packaging, ACVR1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005182
Gene Name ACVR1
Accession Number NM_001105.4
Gene ID 90
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1530 bp
Gene Alias ACTRI,ACVR1A,ACVRLK2,ALK2,FOP,SKR1,TSRI
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTAGATGGAGTGATGATTCTTCCTGTGCTTATCATGATTGCTCTCCCCTCCCCTAGTATGGAAGATGAGAAGCCCAAGGTCAACCCCAAACTCTACATGTGTGTGTGTGAAGGTCTCTCCTGCGGTAATGAGGACCACTGTGAAGGCCAGCAGTGCTTTTCCTCACTGAGCATCAACGATGGCTTCCACGTCTACCAGAAAGGCTGCTTCCAGGTTTATGAGCAGGGAAAGATGACCTGTAAGACCCCGCCGTCCCCTGGCCAAGCCGTGGAGTGCTGCCAAGGGGACTGGTGTAACAGGAACATCACGGCCCAGCTGCCCACTAAAGGAAAATCCTTCCCTGGAACACAGAATTTCCACTTGGAGGTTGGCCTCATTATTCTCTCTGTAGTGTTCGCAGTATGTCTTTTAGCCTGCCTGCTGGGAGTTGCTCTCCGAAAATTTAAAAGGCGCAACCAAGAACGCCTCAATCCCCGAGACGTGGAGTATGGCACTATCGAAGGGCTCATCACCACCAATGTTGGAGACAGCACTTTAGCAGATTTATTGGATCATTCGTGTACATCAGGAAGTGGCTCTGGTCTTCCTTTTCTGGTACAAAGAACAGTGGCTCGCCAGATTACACTGTTGGAGTGTGTCGGGAAAGGCAGGTATGGTGAGGTGTGGAGGGGCAGCTGGCAAGGGGAGAATGTTGCCGTGAAGATCTTCTCCTCCCGTGATGAGAAGTCATGGTTCAGGGAAACGGAATTGTACAACACTGTGATGCTGAGGCATGAAAATATCTTAGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTCGACAAATTGAAAACTGACTGTTGA
ORF Protein Sequence MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T12091-Ab Anti-ACVR1/ ALK-2/ ACTRIA monoclonal antibody
    Target Antigen GM-Tg-g-T12091-Ag ALK-2/ACVR1 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T12091 activin A receptor, type I (ACVR1) protein & antibody
    ORF Viral Vector pGMLP005182 Human ACVR1 Lentivirus plasmid
    ORF Viral Vector pGMAD000055 Human ACVR1 Adenovirus plasmid
    ORF Viral Vector vGMLP005182 Human ACVR1 Lentivirus particle
    ORF Viral Vector vGMAD000055 Human ACVR1 Adenovirus particle


    Target information

    Target ID GM-T12091
    Target Name ACVR1/ALK-2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		90
    Gene ID 100050899 (Equus caballus), 101091298 (Felis catus), 11477 (Mus musculus), 338068 (Bos taurus)
    478757 (Canis lupus familiaris), 697935 (Macaca mulatta), 79558 (Rattus norvegicus), 90 (Homo sapiens)
    Gene Symbols & Synonyms ACVR1,Acvr1,ALK2,Acvr,Alk8,SKR1,Alk-2,Tsk7L,ActR-I,ActRIA,Acvr1a,Acvrlk2,D330013D15Rik,ACVR1A,ActR-IA,FOP,TSRI,ACTRI,ACVRLK2
    Target Alternative Names ACTRI,ACVR1,ACVR1A,ACVRLK2,ALK-2,ALK2,ActR-I,ActR-IA,ActRIA,Activin receptor type I (ACTR-I),Activin receptor type-1,Activin receptor-like kinase 2 (ALK-2),Acvr,Acvr1,Acvr1a,Acvrlk2,Alk-2,Alk8,D330013D15Rik,FOP,SKR1,Serine/threonine-protein kinase receptor R1 (SKR1),TGF-B superfamily receptor type I (TSR-I),TSRI,Tsk7L
    Uniprot Accession P37172,P80201,Q04771,Q28041
    Additional SwissProt Accessions: P37172,Q28041,P80201,Q04771
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease cancer
    Disease from KEGG Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, Fluid shear stress and atherosclerosis
    Gene Ensembl ENSECAG00000018902, ENSMUSG00000026836, ENSBTAG00000011909, ENSCAFG00845026311, ENSMMUG00000018497, ENSG00000115170
    Target Classification Cytokine Receptor, Kinase


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.