Human CXCR4/CD184/D2S201E ORF/cDNA clone-Lentivirus plasmid (NM_003467)

Cat. No.: pGMLP003262
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CXCR4/CD184/D2S201E Lentiviral expression plasmid for CXCR4 lentivirus packaging, CXCR4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003262
Gene Name CXCR4
Accession Number NM_003467
Gene ID 7852
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1059 bp
Gene Alias CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGGGGATCAGTATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGCTAA
ORF Protein Sequence MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-600 Pre-Made Ulocuplumab biosimilar, Whole mAb, Anti-CXCR4 Antibody: Anti-FB22/HM89/LAP3/LCR1/NPYR/WHIM/CD184/LAP-3/LESTR/NPY3R/NPYRL/WHIMS/HSY3RR/NPYY3R/WHIMS1/D2S201E therapeutic antibody
    Target Antibody GM-Tg-g-T96079-Ab Anti-CXCR4/ CD184/ D2S201E monoclonal antibody
    Target Antigen GM-Tg-g-T96079-Ag CXCR4 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T96079 chemokine (C-X-C motif) receptor 4 (CXCR4) protein & antibody
    ORF Viral Vector pGMLP000599 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLP003262 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV000634 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV000695 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV001389 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMPC000631 Human CXCR4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001085 Human CXCR4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000599 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLP003262 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV000634 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV000695 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV001389 Human CXCR4 Lentivirus particle


    Target information

    Target ID GM-T96079
    Target Name CXCR4/CD184
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7852
    Gene ID 100050974 (Equus caballus), 119863891 (Canis lupus familiaris), 12767 (Mus musculus), 281736 (Bos taurus)
    493676 (Felis catus), 60628 (Rattus norvegicus), 707329 (Macaca mulatta), 7852 (Homo sapiens)
    Gene Symbols & Synonyms CXCR4,Cxcr4,CD184,LESTR,Sdf1r,CXC-R4,CXCR-4,Cmkar4,PB-CKR,b2b220Clo,PBSF/SDF-1,FB22,HM89,LAP3,LCR1,NPYR,WHIM,LAP-3,NPY3R,NPYRL,WHIMS,HSY3RR,NPYY3R,WHIMS1,D2S201E
    Target Alternative Names C-X-C chemokine receptor type 4,CD184,CXC-R4,CXCR-4,CXCR4,Cmkar4,Cxcr4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,LPS-associated protein 3),Leukocyte-derived seven transmembrane domain receptor (LESTR),Lipopolysaccharide-associated protein 3 (LAP-3,NPY3R,NPYR,NPYRL,NPYY3R,PB-CKR,PBSF/SDF-1,Sdf1r,Stromal cell-derived factor 1 receptor (SDF-1 receptor),WHIM,WHIMS,WHIMS1,b2b220Clo
    Uniprot Accession O08565,P25930,P56498,P61073,P70658,P79394
    Additional SwissProt Accessions: P70658,P25930,P56498,O08565,P79394,P61073
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease cancer
    Disease from KEGG Calcium signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Axon guidance, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer
    Gene Ensembl ENSECAG00000003837, ENSCAFG00845010172,ENSCAFG00845025560, ENSMUSG00000045382, ENSMMUG00000011918, ENSG00000121966
    Target Classification GPCR, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.