Human GSDMD/DF5L/DFNA5L ORF/cDNA clone-Lentivirus plasmid (NM_024736)

Cat. No.: pGMLP003197
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GSDMD/DF5L/DFNA5L Lentiviral expression plasmid for GSDMD lentivirus packaging, GSDMD lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003197
Gene Name GSDMD
Accession Number NM_024736
Gene ID 79792
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1455 bp
Gene Alias DF5L,DFNA5L,FKSG10,GSDMDC1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGGTCGGCCTTTGAGCGGGTAGTCCGGAGAGTGGTCCAGGAGCTGGACCATGGTGGGGAGTTCATCCCTGTGACCAGCCTGCAGAGCTCCACTGGCTTCCAGCCCTACTGCCTGGTGGTTAGGAAGCCCTCAAGCTCATGGTTCTGGAAACCCCGTTATAAGTGTGTCAACCTGTCTATCAAGGACATCCTGGAGCCGGATGCCGCGGAACCAGACGTGCAGCGTGGCAGGAGCTTCCACTTCTACGATGCCATGGATGGGCAGATACAGGGCAGCGTGGAGCTGGCAGCCCCAGGACAGGCAAAGATCGCAGGCGGGGCCGCGGTGTCTGACAGCTCCAGCACCTCAATGAATGTGTACTCGCTGAGTGTGGACCCTAACACCTGGCAGACTCTGCTCCATGAGAGGCACCTGCGGCAGCCAGAACACAAAGTCCTGCAGCAGCTGCGCAGCCGCGGGGACAACGTGTACGTGGTGACTGAGGTGCTGCAGACACAGAAGGAGGTGGAAGTCACGCGCACCCACAAGCGGGAGGGCTCGGGCCGGTTTTCCCTGCCCGGAGCCACGTGCTTGCAGGGTGAGGGCCAGGGCCATCTGAGCCAGAAGAAGACGGTCACCATCCCCTCAGGCAGCACCCTCGCATTCCGGGTGGCCCAGCTGGTTATTGACTCTGACTTGGACGTCCTTCTCTTCCCGGATAAGAAGCAGAGGACCTTCCAGCCACCCGCGACAGGCCACAAGCGTTCCACGAGCGAAGGCGCCTGGCCACAGCTGCCCTCTGGCCTCTCCATGATGAGGTGCCTCCACAACTTCCTGACAGATGGGGTCCCTGCGGAGGGGGCGTTCACTGAAGACTTCCAGGGCCTACGGGCAGAGGTGGAGACCATCTCCAAGGAACTGGAGCTTTTGGACAGAGAGCTGTGCCAGCTGCTGCTGGAGGGCCTGGAGGGGGTGCTGCGGGACCAGCTGGCCCTGCGAGCCTTGGAGGAGGCGCTGGAGCAGGGCCAGAGCCTTGGGCCGGTGGAGCCCCTGGACGGTCCAGCAGGTGCTGTCCTGGAGTGCCTGGTGTTGTCCTCCGGAATGCTGGTGCCGGAACTCGCTATCCCTGTTGTCTACCTGCTGGGGGCACTGACCATGCTGAGTGAAACGCAGCACAAGCTGCTGGCGGAGGCGCTGGAGTCGCAGACCCTGTTGGGGCCGCTCGAGCTGGTGGGCAGCCTCTTGGAGCAGAGTGCCCCGTGGCAGGAGCGCAGCACCATGTCCCTGCCCCCCGGGCTCCTGGGGAACAGCTGGGGCGAAGGAGCACCGGCCTGGGTCTTGCTGGACGAGTGTGGCCTAGAGCTGGGGGAGGACACTCCCCACGTGTGCTGGGAGCCGCAGGCCCAGGGCCGCATGTGTGCACTCTACGCCTCCCTGGCACTGCTATCAGGACTGAGCCAGGAGCCCCACTAG
ORF Protein Sequence MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLSIKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQEPH

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2580-Ab Anti-GSDMD/ DF5L/ DFNA5L monoclonal antibody
    Target Antigen GM-Tg-g-MP2580-Ag GSDMD VLP (virus-like particle)
    ORF Viral Vector pGMLP003197 Human GSDMD Lentivirus plasmid
    ORF Viral Vector pGMLV001966 Human GSDMD Lentivirus plasmid
    ORF Viral Vector pGMPC000382 Human GSDMD Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000461 Human GSDMD Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001214 Human GSDMD Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP003197 Human GSDMD Lentivirus particle
    ORF Viral Vector vGMLV001966 Human GSDMD Lentivirus particle


    Target information

    Target ID GM-MP2580
    Target Name GSDMD
    Gene Group Identifier
    （Target Gene ID in Homo species)         		79792
    Gene ID 100063519 (Equus caballus), 101089493 (Felis catus), 315084 (Rattus norvegicus), 513939 (Bos taurus)
    609395 (Canis lupus familiaris), 69146 (Mus musculus), 697137 (Macaca mulatta), 79792 (Homo sapiens)
    Gene Symbols & Synonyms GSDMD,Gsdmd,Gsdmdc1,GSDMDC1,DF5L,M2-4,Dfna5l,GsdmD-1,1810036L03Rik,DFNA5L,FKSG10
    Target Alternative Names 1810036L03Rik,DF5L,DFNA5L,Dfna5l,FKSG10,GSDMD,GSDMDC1,Gasdermin domain-containing protein 1,Gasdermin-D,GsdmD-1,Gsdmd,Gsdmdc1,M2-4
    Uniprot Accession P57764,Q9D8T2
    Additional SwissProt Accessions: Q9D8T2,P57764
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category
    Disease
    Disease from KEGG NOD-like receptor signaling pathway
    Gene Ensembl ENSBTAG00000021474, ENSCAFG00845015279, ENSMUSG00000022575, ENSMMUG00000001633, ENSG00000104518
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.