Human BECN1/ATG6/beclin1 ORF/cDNA clone-Lentivirus plasmid (NM_003766)

Cat. No.: pGMLP002723
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human BECN1/ATG6/beclin1 Lentiviral expression plasmid for BECN1 lentivirus packaging, BECN1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002723
Gene Name BECN1
Accession Number NM_003766
Gene ID 8678
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1353 bp
Gene Alias ATG6,beclin1,VPS30
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAAGGGTCTAAGACGTCCAACAACAGCACCATGCAGGTGAGCTTCGTGTGCCAGCGCTGCAGCCAGCCCCTGAAACTGGACACGAGTTTCAAGATCCTGGACCGTGTCACCATCCAGGAACTCACAGCTCCATTACTTACCACAGCCCAGGCGAAACCAGGAGAGACCCAGGAGGAAGAGACTAACTCAGGAGAGGAGCCATTTATTGAAACTCCTCGCCAGGATGGTGTCTCTCGCAGATTCATCCCCCCAGCCAGGATGATGTCCACAGAAAGTGCCAACAGCTTCACTCTGATTGGGGAGGCATCTGATGGCGGCACCATGGAGAACCTCAGCCGAAGACTGAAGGTCACTGGGGACCTTTTTGACATCATGTCGGGCCAGACAGATGTGGATCACCCACTCTGTGAGGAATGCACAGATACTCTTTTAGACCAGCTGGACACTCAGCTCAACGTCACTGAAAATGAGTGTCAGAACTACAAACGCTGTTTGGAGATCTTAGAGCAAATGAATGAGGATGACAGTGAACAGTTACAGATGGAGCTAAAGGAGCTGGCACTAGAGGAGGAGAGGCTGATCCAGGAGCTGGAAGACGTGGAAAAGAACCGCAAGATAGTGGCAGAAAATCTCGAGAAGGTCCAGGCTGAGGCTGAGAGACTGGATCAGGAGGAAGCTCAGTATCAGAGAGAATACAGTGAATTTAAACGACAGCAGCTGGAGCTGGATGATGAGCTGAAGAGTGTTGAAAACCAGATGCGTTATGCCCAGACGCAGCTGGATAAGCTGAAGAAAACCAACGTCTTTAATGCAACCTTCCACATCTGGCACAGTGGACAGTTTGGCACAATCAATAACTTCAGGCTGGGTCGCCTGCCCAGTGTTCCCGTGGAATGGAATGAGATTAATGCTGCTTGGGGCCAGACTGTGTTGCTGCTCCATGCTCTGGCCAATAAGATGGGTCTGAAATTTCAGAGATACCGACTTGTTCCTTACGGAAACCATTCATATCTGGAGTCTCTGACAGACAAATCTAAGGAGCTGCCGTTATACTGTTCTGGGGGGTTGCGGTTTTTCTGGGACAACAAGTTTGACCATGCAATGGTGGCTTTCCTGGACTGTGTGCAGCAGTTCAAAGAAGAGGTTGAGAAAGGCGAGACACGTTTTTGTCTTCCCTACAGGATGGATGTGGAGAAAGGCAAGATTGAAGACACAGGAGGCAGTGGCGGCTCCTATTCCATCAAAACCCAGTTTAACTCTGAGGAGCAGTGGACAAAAGCTCTCAAGTTCATGCTGACGAATCTTAAGTGGGGTCTTGCTTGGGTGTCCTCACAATTTTATAACAAATGA
ORF Protein Sequence MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T84616-Ab Anti-BECN1 monoclonal antibody
    Target Antigen GM-Tg-g-T84616-Ag BECN1 protein
    ORF Viral Vector pGMLP002723 Human BECN1 Lentivirus plasmid
    ORF Viral Vector pGMLP-atg-005 Human BECN1 Lentivirus plasmid
    ORF Viral Vector pGMAP-atg-059 Human BECN1 Adenovirus plasmid
    ORF Viral Vector pGMPC001612 Human BECN1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002723 Human BECN1 Lentivirus particle
    ORF Viral Vector vGMLP-atg-005 Human BECN1 Lentivirus particle
    ORF Viral Vector vGMAP-atg-059 Human BECN1 Adenovirus particle


    Target information

    Target ID GM-T84616
    Target Name Beclin 1/BECN1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		8678
    Gene ID 100052295 (Equus caballus), 101101015 (Felis catus), 114558 (Rattus norvegicus), 480513 (Canis lupus familiaris)
    527278 (Bos taurus), 56208 (Mus musculus), 711649 (Macaca mulatta), 8678 (Homo sapiens)
    Gene Symbols & Synonyms BECN1,Becn1,Beclin1,ATG6,Atg6,beclin-1,VPS30,beclin1
    Target Alternative Names ATG6,Atg6,BECN1,Beclin 1,Beclin-1,Beclin1,Becn1,Coiled-coil myosin-like BCL2-interacting protein,Protein GT197,VPS30,beclin-1,beclin1
    Uniprot Accession O88597,Q14457,Q4A1L4,Q91XJ1
    Additional SwissProt Accessions: Q91XJ1,Q4A1L4,O88597,Q14457
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer, gastric cancer
    Disease from KEGG Apoptosis - multiple species, Alzheimer disease, Kaposi sarcoma-associated herpesvirus infection
    Gene Ensembl ENSECAG00000018079, ENSCAFG00845007505, ENSBTAG00000019914, ENSMUSG00000035086, ENSMMUG00000029971, ENSG00000126581
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.