Human XIAP/API3/BIRC4 ORF/cDNA clone-Lentivirus plasmid (NM_001167)

Cat. No.: pGMLP002221
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human XIAP/API3/BIRC4 Lentiviral expression plasmid for XIAP lentivirus packaging, XIAP lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002221
Gene Name XIAP
Accession Number NM_001167
Gene ID 331
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1494 bp
Gene Alias API3,BIRC4,hIAP-3,hIAP3,IAP-3,ILP1,MIHA,XLP2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAGAAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTCCTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCGTGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTGGAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATAGTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATCTGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTTTGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGTATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCCCAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCTTTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACAGGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAATCTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCATCCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACAAGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCTTTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATGCTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACAATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCATCACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATACGAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTGGGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACAGTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGCTAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCGTTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGTGTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAA
ORF Protein Sequence MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0058-Ab Anti-XIAP monoclonal antibody
    Target Antigen GM-Tg-g-IP0058-Ag XIAP protein
    ORF Viral Vector pGMLP002221 Human XIAP Lentivirus plasmid
    ORF Viral Vector pGMLV000630 Human XIAP Lentivirus plasmid
    ORF Viral Vector pGMPC001434 Human XIAP Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002221 Human XIAP Lentivirus particle
    ORF Viral Vector vGMLV000630 Human XIAP Lentivirus particle


    Target information

    Target ID GM-IP0058
    Target Name XIAP
    Gene Group Identifier
    （Target Gene ID in Homo species)         		331
    Gene ID 100060870 (Equus caballus), 101090594 (Felis catus), 11798 (Mus musculus), 281647 (Bos taurus)
    331 (Homo sapiens), 442989 (Canis lupus familiaris), 63879 (Rattus norvegicus), 698057 (Macaca mulatta)
    Gene Symbols & Synonyms XIAP,Xiap,Aipa,Api3,IAP3,MIHA,Birc4,ILP-1,1110015C02Rik,BIRC4,API3,ILP1,XLP2,IAP-3,hIAP3,hIAP-3,riap3
    Target Alternative Names 1110015C02Rik,API3,Aipa,Api3,BIRC4,Baculoviral IAP repeat-containing protein 4,Birc4,E3 ubiquitin-protein ligase XIAP,IAP-3,IAP-like protein (ILP,IAP3,ILP-1,ILP1,Inhibitor of apoptosis protein 3 (IAP-3,MIHA,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein (X-linked IAP),XIAP,XLP2,Xiap,hIAP-3,hIAP3,hIAP3),hILP),riap3
    Uniprot Accession P98170,Q60989,Q9R0I6
    Additional SwissProt Accessions: Q60989,P98170,Q9R0I6
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease cancer
    Disease from KEGG NF-kappa B signaling pathway, Apoptosis, Apoptosis - multiple species, Focal adhesion, NOD-like receptor signaling pathway, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Small cell lung cancer
    Gene Ensembl ENSECAG00000020071, ENSMUSG00000025860, ENSBTAG00000040350, ENSG00000101966, ENSCAFG00845025680, ENSMMUG00000032353
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.