Human ICOSLG/B7-H2/B7H2 ORF/cDNA clone-Lentivirus plasmid (NM_015259)

Cat. No.: pGMLP002122
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human ICOSLG/B7-H2/B7H2 Lentiviral expression plasmid for ICOSLG lentivirus packaging, ICOSLG lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002122
Gene Name ICOSLG
Accession Number NM_015259
Gene ID 23308
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 909 bp
Gene Alias B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGGCTGGGCAGTCCTGGACTGCTCTTCCTGCTCTTCAGCAGCCTTCGAGCTGATACTCAGGAGAAGGAAGTCAGAGCGATGGTAGGCAGCGACGTGGAGCTCAGCTGCGCTTGCCCTGAAGGAAGCCGTTTTGATTTAAATGATGTTTACGTATATTGGCAAACCAGTGAGTCGAAAACCGTGGTGACCTACCACATCCCACAGAACAGCTCCTTGGAAAACGTGGACAGCCGCTACCGGAACCGAGCCCTGATGTCACCGGCCGGCATGCTGCGGGGCGACTTCTCCCTGCGCTTGTTCAACGTCACCCCCCAGGACGAGCAGAAGTTTCACTGCCTGGTGTTGAGCCAATCCCTGGGATTCCAGGAGGTTTTGAGCGTTGAGGTTACACTGCATGTGGCAGCAAACTTCAGCGTGCCCGTCGTCAGCGCCCCCCACAGCCCCTCCCAGGATGAGCTCACCTTCACGTGTACATCCATAAACGGCTACCCCAGGCCCAACGTGTACTGGATCAATAAGACGGACAACAGCCTGCTGGACCAGGCTCTGCAGAATGACACCGTCTTCTTGAACATGCGGGGCTTGTATGACGTGGTCAGCGTGCTGAGGATCGCACGGACCCCCAGCGTGAACATTGGCTGCTGCATAGAGAACGTGCTTCTGCAGCAGAACCTGACTGTCGGCAGCCAGACAGGAAATGACATCGGAGAGAGAGACAAGATCACAGAGAATCCAGTCAGTACCGGCGAGAAAAACGCGGCCACGTGGAGCATCCTGGCTGTCCTGTGCCTGCTTGTGGTCGTGGCGGTGGCCATAGGCTGGGTGTGCAGGGACCGATGCCTCCAACACAGCTATGCAGGTGCCTGGGCTGTGAGTCCGGAGACAGAGCTCACTGGCCACGTTTGA
ORF Protein Sequence MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTGHV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-456 Pre-Made Prezalumab biosimilar, Whole mAb, Anti-ICOSLG/B7RP1 Antibody: Anti-B7-H2/B7H2/B7h/CD275/GL50/ICOS-L/ICOSL/LICOS therapeutic antibody
    Target Antibody GM-Tg-g-T16144-Ab Anti-ICOSL/ B7RP1/ ICOSLG monoclonal antibody
    Target Antigen GM-Tg-g-T16144-Ag B7RP1/ICOSLG VLP (virus-like particle)
    ORF Viral Vector pGMLP002122 Human ICOSLG Lentivirus plasmid
    ORF Viral Vector vGMLP002122 Human ICOSLG Lentivirus particle


    Target information

    Target ID GM-T16144
    Target Name ICOSLG/B7-H2/CD275/B7RP1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		23308
    Gene ID 100057048 (Equus caballus), 101091550 (Felis catus), 23308 (Homo sapiens), 487793 (Canis lupus familiaris)
    499415 (Rattus norvegicus), 50723 (Mus musculus), 507857 (Bos taurus), 722191 (Macaca mulatta)
    Gene Symbols & Synonyms ICOSLG,Icoslg,Icosl,B7h,B7H2,GL50,B7-H2,B7RP1,CD275,ICOSL,LICOS,B7RP-1,ICOS-L,IMD119,RGD1562791,GI50,GL50-B,Ly115l,mKIAA0653
    Target Alternative Names B7 homolog 2 (B7-H2),B7-H2,B7-like protein Gl50,B7-related protein 1 (B7RP-1),B7H2,B7RP-1,B7RP1,B7h,CD275,GI50,GL50,GL50-B,ICOS ligand,ICOS-L,ICOSL,ICOSLG,IMD119,Icosl,Icoslg,LICOS,Ly115l,RGD1562791,mKIAA0653
    Uniprot Accession O75144,Q9JHJ8
    Additional SwissProt Accessions: O75144,Q9JHJ8
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index
    Disease
    Disease from KEGG Cell adhesion molecules, Intestinal immune network for IgA production
    Gene Ensembl ENSECAG00000051827, ENSG00000160223, ENSCAFG00845019541, ENSMUSG00000000732, ENSBTAG00000014880, ENSMMUG00000010647
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.