Human CYBB/AMCBX2/CGD ORF/cDNA clone-Lentivirus plasmid (NM_000397)

Cat. No.: pGMLP002072
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CYBB/AMCBX2/CGD Lentiviral expression plasmid for CYBB lentivirus packaging, CYBB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002072
Gene Name CYBB
Accession Number NM_000397
Gene ID 1536
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1713 bp
Gene Alias AMCBX2,CGD,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGGAACTGGGCTGTGAATGAGGGGCTCTCCATTTTTGTCATTCTGGTTTGGCTGGGGTTGAACGTCTTCCTCTTTGTCTGGTATTACCGGGTTTATGATATTCCACCTAAGTTCTTTTACACAAGAAAACTTCTTGGGTCAGCACTGGCACTGGCCAGGGCCCCTGCAGCCTGCCTGAATTTCAACTGCATGCTGATTCTCTTGCCAGTCTGTCGAAATCTGCTGTCCTTCCTCAGGGGTTCCAGTGCGTGCTGCTCAACAAGAGTTCGAAGACAACTGGACAGGAATCTCACCTTTCATAAAATGGTGGCATGGATGATTGCACTTCACTCTGCGATTCACACCATTGCACATCTATTTAATGTGGAATGGTGTGTGAATGCCCGAGTCAATAATTCTGATCCTTATTCAGTAGCACTCTCTGAACTTGGAGACAGGCAAAATGAAAGTTATCTCAATTTTGCTCGAAAGAGAATAAAGAACCCTGAAGGAGGCCTGTACCTGGCTGTGACCCTGTTGGCAGGCATCACTGGAGTTGTCATCACGCTGTGCCTCATATTAATTATCACTTCCTCCACCAAAACCATCCGGAGGTCTTACTTTGAAGTCTTTTGGTACACACATCATCTCTTTGTGATCTTCTTCATTGGCCTTGCCATCCATGGAGCTGAACGAATTGTACGTGGGCAGACCGCAGAGAGTTTGGCTGTGCATAATATAACAGTTTGTGAACAAAAAATCTCAGAATGGGGAAAAATAAAGGAATGCCCAATCCCTCAGTTTGCTGGAAACCCTCCTATGACTTGGAAATGGATAGTGGGTCCCATGTTTCTGTATCTCTGTGAGAGGTTGGTGCGGTTTTGGCGATCTCAACAGAAGGTGGTCATCACCAAGGTGGTCACTCACCCTTTCAAAACCATCGAGCTACAGATGAAGAAGAAGGGGTTCAAAATGGAAGTGGGACAATACATTTTTGTCAAGTGCCCAAAGGTGTCCAAGCTGGAGTGGCACCCTTTTACACTGACATCCGCCCCTGAGGAAGACTTCTTTAGTATCCATATCCGCATCGTTGGGGACTGGACAGAGGGGCTGTTCAATGCTTGTGGCTGTGATAAGCAGGAGTTTCAAGATGCGTGGAAACTACCTAAGATAGCGGTTGATGGGCCCTTTGGCACTGCCAGTGAAGATGTGTTCAGCTATGAGGTGGTGATGTTAGTGGGAGCAGGGATTGGGGTCACACCCTTCGCATCCATTCTCAAGTCAGTCTGGTACAAATATTGCAATAACGCCACCAATCTGAAGCTCAAAAAGATCTACTTCTACTGGCTGTGCCGGGACACACATGCCTTTGAGTGGTTTGCAGATCTGCTGCAACTGCTGGAGAGCCAGATGCAGGAAAGGAACAATGCCGGCTTCCTCAGCTACAACATCTACCTCACTGGCTGGGATGAGTCTCAGGCCAATCACTTTGCTGTGCACCATGATGAGGAGAAAGATGTGATCACAGGCCTGAAACAAAAGACTTTGTATGGACGGCCCAACTGGGATAATGAATTCAAGACAATTGCAAGTCAACACCCTAATACCAGAATAGGAGTTTTCCTCTGTGGACCTGAAGCCTTGGCTGAAACCCTGAGTAAACAAAGCATCTCCAACTCTGAGTCTGGCCCTCGGGGAGTGCATTTCATTTTCAACAAGGAAAACTTCTAA
ORF Protein Sequence MGNWAVNEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCNNATNLKLKKIYFYWLCRDTHAFEWFADLLQLLESQMQERNNAGFLSYNIYLTGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPEALAETLSKQSISNSESGPRGVHFIFNKENF

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T36729-Ab Anti-CY24B/ CYBB/ AMCBX2 monoclonal antibody
    Target Antigen GM-Tg-g-T36729-Ag CYBB VLP (virus-like particle)
    ORF Viral Vector pGMLP002072 Human CYBB Lentivirus plasmid
    ORF Viral Vector pGMPC001103 Human CYBB Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002072 Human CYBB Lentivirus particle


    Target information

    Target ID GM-T36729
    Target Name NOX2/CYBB
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1536
    Gene ID 100050132 (Equus caballus), 101086207 (Felis catus), 13058 (Mus musculus), 1536 (Homo sapiens)
    281112 (Bos taurus), 491825 (Canis lupus familiaris), 66021 (Rattus norvegicus), 696542 (Macaca mulatta)
    Gene Symbols & Synonyms CYBB,Cybb,Cgd,Cyd,Nox2,gp91-1,gp91phox,CGD91-phox,CGD,CGDX,NOX2,IMD34,AMCBX2,GP91-1,GP91PHOX,p91-PHOX,GP91-PHOX,Gp91-phox
    Target Alternative Names AMCBX2,CGD,CGD91-phox,CGDX,CYBB,Cgd,Cybb,Cyd,Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta),Cytochrome b-245 heavy chain,GP91-1,GP91-PHOX,GP91PHOX,Gp91-phox,Heme-binding membrane glycoprotein gp91phox,IMD34,NADPH oxidase 2,NOX2,Neutrophil cytochrome b 91 kDa polypeptide,Nox2,Superoxide-generating NADPH oxidase heavy chain subunit,gp91-1,gp91-phox,gp91phox,p22 phagocyte B-cytochrome,p91-PHOX
    Uniprot Accession O46522,P04839,Q61093
    Additional SwissProt Accessions: Q61093,P04839,O46522
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG HIF-1 signaling pathway, Phagosome, Ferroptosis, NOD-like receptor signaling pathway, Leukocyte transendothelial migration, AGE-RAGE signaling pathway in diabetic complications, Alzheimer disease, Leishmaniasis, Lipid and atherosclerosis
    Gene Ensembl ENSECAG00000017917, ENSMUSG00000015340, ENSG00000165168, ENSBTAG00000019953, ENSCAFG00845023727, ENSMMUG00000013220
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.