Human DKK1/DKK-1/SK ORF/cDNA clone-Lentivirus plasmid (NM_012242.3)

Cat. No.: pGMLP001886
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DKK1/DKK-1/SK Lentiviral expression plasmid for DKK1 lentivirus packaging, DKK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001886
Gene Name DKK1
Accession Number NM_012242.3
Gene ID 22943
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 801 bp
Gene Alias DKK-1,SK
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGATGGCTCTGGGCGCAGCGGGAGCTACCCGGGTCTTTGTCGCGATGGTAGCGGCGGCTCTCGGCGGCCACCCTCTGCTGGGAGTGAGCGCCACCTTGAACTCGGTTCTCAATTCCAACGCTATCAAGAACCTGCCCCCACCGCTGGGCGGCGCTGCGGGGCACCCAGGCTCTGCAGTCAGCGCCGCGCCGGGAATCCTGTACCCGGGCGGGAATAAGTACCAGACCATTGACAACTACCAGCCGTACCCGTGCGCAGAGGACGAGGAGTGCGGCACTGATGAGTACTGCGCTAGTCCCACCCGCGGAGGGGACGCAGGCGTGCAAATCTGTCTCGCCTGCAGGAAGCGCCGAAAACGCTGCATGCGTCACGCTATGTGCTGCCCCGGGAATTACTGCAAAAATGGAATATGTGTGTCTTCTGATCAAAATCATTTCCGAGGAGAAATTGAGGAAACCATCACTGAAAGCTTTGGTAATGATCATAGCACCTTGGATGGGTATTCCAGAAGAACCACCTTGTCTTCAAAAATGTATCACACCAAAGGACAAGAAGGTTCTGTTTGTCTCCGGTCATCAGACTGTGCCTCAGGATTGTGTTGTGCTAGACACTTCTGGTCCAAGATCTGTAAACCTGTCCTGAAAGAAGGTCAAGTGTGTACCAAGCATAGGAGAAAAGGCTCTCATGGACTAGAAATATTCCAGCGTTGTTACTGTGGAGAAGGTCTGTCTTGCCGGATACAGAAAGATCACCATCAAGCCAGTAATTCTTCTAGGCTTCACACTTGTCAGAGACACTAA
ORF Protein Sequence MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-694 Pre-Made Sirexatamab biosimilar, Whole mAb, Anti-DKK1 Antibody: Anti-SK/DKK-1 therapeutic antibody
    Target Antibody GM-Tg-g-T56697-Ab Anti-DKK1/ DKK-1/ SK monoclonal antibody
    Target Antigen GM-Tg-g-T56697-Ag DKK1 VLP (virus-like particle)
    ORF Viral Vector pGMLP001886 Human DKK1 Lentivirus plasmid
    ORF Viral Vector pGMLV002350 Human DKK1 Lentivirus plasmid
    ORF Viral Vector vGMLP001886 Human DKK1 Lentivirus particle
    ORF Viral Vector vGMLV002350 Human DKK1 Lentivirus particle


    Target information

    Target ID GM-T56697
    Target Name DKK1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		22943
    Gene ID 100071881 (Equus caballus), 101097173 (Felis catus), 13380 (Mus musculus), 22943 (Homo sapiens)
    293897 (Rattus norvegicus), 504445 (Bos taurus), 609600 (Canis lupus familiaris), 702997 (Macaca mulatta)
    Gene Symbols & Synonyms DKK1,Dkk1,mdkk-1,SK,DKK-1
    Target Alternative Names DKK-1,DKK1,Dickkopf-1,Dickkopf-related protein 1,Dkk-1,Dkk1,SK,hDkk-1,mdkk-1
    Uniprot Accession O54908,O94907
    Additional SwissProt Accessions: O54908,O94907
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index
    Disease cancer
    Disease from KEGG Wnt signaling pathway, Alzheimer disease
    Gene Ensembl ENSECAG00000017837, ENSMUSG00000024868, ENSG00000107984, ENSBTAG00000014218, ENSMMUG00000010847
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.