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Human GREM1/C15DUPq/CKTSF1B1 ORF/cDNA clone-Lentivirus plasmid (NM_013372)
Cat. No.: pGMLP000730
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human GREM1/C15DUPq/CKTSF1B1 Lentiviral expression plasmid for GREM1 lentivirus packaging, GREM1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
Datasheet
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Product Description
| Catalog ID | pGMLP000730 |
| Gene Name | GREM1 |
| Accession Number | NM_013372 |
| Gene ID | 26585 |
| Species | Human |
| Product Type | Lentivirus plasmid (overexpression) |
| Insert Length | 555 bp |
| Gene Alias | C15DUPq,CKTSF1B1,CRAC1,CRCS4,DAND2,DRM,DUP15q,GREMLIN,HMPS,HMPS1,IHG-2,MPSH,PIG2 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAGCCGCACAGCCTACACGGTGGGAGCCCTGCTTCTCCTCTTGGGGACCCTGCTGCCGGCTGCTGAAGGGAAAAAGAAAGGGTCCCAAGGTGCCATCCCCCCGCCAGACAAGGCCCAGCACAATGACTCAGAGCAGACTCAGTCGCCCCAGCAGCCTGGCTCCAGGAACCGGGGGCGGGGCCAAGGGCGGGGCACTGCCATGCCCGGGGAGGAGGTGCTGGAGTCCAGCCAAGAGGCCCTGCATGTGACGGAGCGCAAATACCTGAAGCGAGACTGGTGCAAAACCCAGCCGCTTAAGCAGACCATCCACGAGGAAGGCTGCAACAGTCGCACCATCATCAACCGCTTCTGTTACGGCCAGTGCAACTCTTTCTACATCCCCAGGCACATCCGGAAGGAGGAAGGTTCCTTTCAGTCCTGCTCCTTCTGCAAGCCCAAGAAATTCACTACCATGATGGTCACACTCAACTGCCCTGAACTACAGCCACCTACCAAGAAGAAGAGAGTCACACGTGTGAAGCAGTGTCGTTGCATATCCATCGATTTGGATTAA |
| ORF Protein Sequence | MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-669 | Pre-Made Ginisortamab biosimilar, Whole mAb, Anti-GREM1/Gremlin-1 Antibody: Anti-C15DUPq/CKTSF1B1/CRAC1/CRCS4/DAND2/DRM/DUP15q/GREMLIN/HMPS/HMPS1/IHG-2/MPSH/PIG2 therapeutic antibody |
| Target Antibody | GM-Tg-g-T22104-Ab | Anti-GREM1/ Gremlin-1/ C15DUPq functional antibody |
| Target Antigen | GM-Tg-g-T22104-Ag | Gremlin-1/GREM1 protein |
| ORF Viral Vector | pGMLP000730 | Human GREM1 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000730 | Human GREM1 Adenovirus plasmid |
| ORF Viral Vector | vGMLP000730 | Human GREM1 Lentivirus particle |
| ORF Viral Vector | vGMAD000730 | Human GREM1 Adenovirus particle |
Target information
| Target ID | GM-T22104 |
| Target Name | GREM1/Gremlin-1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
26585 |
| Gene ID |
100057765 (Equus caballus), 101096735 (Felis catus), 23892 (Mus musculus), 26585 (Homo sapiens) 487475 (Canis lupus familiaris), 50566 (Rattus norvegicus), 539079 (Bos taurus), 574176 (Macaca mulatta) |
| Gene Symbols & Synonyms | GREM1,Grem1,ld,Drm,Grem,Cktsf1b1,DRM,HMPS,MPSH,PIG2,CRAC1,CRCS4,DAND2,HMPS1,IHG-2,DUP15q,C15DUPq,GREMLIN,CKTSF1B1,drm,gremlin-1 |
| Target Alternative Names | GREM1, Gremlin-1,Gremlin-1,Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, Down-regulated in Mos-transformed cells protein, Increased in high glucose protein 2 (IHG-2),DRM,HMPS,MPSH,PIG2,CRAC1,CRCS4,DAND2,HMPS1,IHG-2,DUP15q,C15DUPq,GREMLIN,CKTSF1B1 |
| Uniprot Accession |
O35793,O60565,O70326,Q8WNY1
Additional SwissProt Accessions: O70326,O60565,O35793,Q8WNY1 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index |
| Disease | cancer |
| Disease from KEGG | TGF-beta signaling pathway |
| Gene Ensembl | ENSECAG00000044796, ENSMUSG00000074934, ENSG00000166923, ENSBTAG00000050495, ENSMMUG00000001810 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
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