Human TGFBR2/AAT3/FAA3 ORF/cDNA clone-Lentivirus plasmid (NM_001024847)

Cat. No.: pGMLP-SPh-041
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TGFBR2/AAT3/FAA3 Lentiviral expression plasmid for TGFBR2 lentivirus packaging, TGFBR2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-SPh-041
Gene Name TGFBR2
Accession Number NM_001024847
Gene ID 7048
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1779 bp
Gene Alias AAT3,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,TAAD2,TGFbeta-RII,TGFR-2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGTCGGGGGCTGCTCAGGGGCCTGTGGCCGCTGCACATCGTCCTGTGGACGCGTATCGCCAGCACGATCCCACCGCACGTTCAGAAGTCGGATGTGGAAATGGAGGCCCAGAAAGATGAAATCATCTGCCCCAGCTGTAATAGGACTGCCCATCCACTGAGACATATTAATAACGACATGATAGTCACTGACAACAACGGTGCAGTCAAGTTTCCACAACTGTGTAAATTTTGTGATGTGAGATTTTCCACCTGTGACAACCAGAAATCCTGCATGAGCAACTGCAGCATCACCTCCATCTGTGAGAAGCCACAGGAAGTCTGTGTGGCTGTATGGAGAAAGAATGACGAGAACATAACACTAGAGACAGTTTGCCATGACCCCAAGCTCCCCTACCATGACTTTATTCTGGAAGATGCTGCTTCTCCAAAGTGCATTATGAAGGAAAAAAAAAAGCCTGGTGAGACTTTCTTCATGTGTTCCTGTAGCTCTGATGAGTGCAATGACAACATCATCTTCTCAGAAGAATATAACACCAGCAATCCTGACTTGTTGCTAGTCATATTTCAAGTGACAGGCATCAGCCTCCTGCCACCACTGGGAGTTGCCATATCTGTCATCATCATCTTCTACTGCTACCGCGTTAACCGGCAGCAGAAGCTGAGTTCAACCTGGGAAACCGGCAAGACGCGGAAGCTCATGGAGTTCAGCGAGCACTGTGCCATCATCCTGGAAGATGACCGCTCTGACATCAGCTCCACGTGTGCCAACAACATCAACCACAACACAGAGCTGCTGCCCATTGAGCTGGACACCCTGGTGGGGAAAGGTCGCTTTGCTGAGGTCTATAAGGCCAAGCTGAAGCAGAACACTTCAGAGCAGTTTGAGACAGTGGCAGTCAAGATCTTTCCCTATGAGGAGTATGCCTCTTGGAAGACAGAGAAGGACATCTTCTCAGACATCAATCTGAAGCATGAGAACATACTCCAGTTCCTGACGGCTGAGGAGCGGAAGACGGAGTTGGGGAAACAATACTGGCTGATCACCGCCTTCCACGCCAAGGGCAACCTACAGGAGTACCTGACGCGGCATGTCATCAGCTGGGAGGACCTGCGCAAGCTGGGCAGCTCCCTCGCCCGGGGGATTGCTCACCTCCACAGTGATCACACTCCATGTGGGAGGCCCAAGATGCCCATCGTGCACAGGGACCTCAAGAGCTCCAATATCCTCGTGAAGAACGACCTAACCTGCTGCCTGTGTGACTTTGGGCTTTCCCTGCGTCTGGACCCTACTCTGTCTGTGGATGACCTGGCTAACAGTGGGCAGGTGGGAACTGCAAGATACATGGCTCCAGAAGTCCTAGAATCCAGGATGAATTTGGAGAATGTTGAGTCCTTCAAGCAGACCGATGTCTACTCCATGGCTCTGGTGCTCTGGGAAATGACATCTCGCTGTAATGCAGTGGGAGAAGTAAAAGATTATGAGCCTCCATTTGGTTCCAAGGTGCGGGAGCACCCCTGTGTCGAAAGCATGAAGGACAACGTGTTGAGAGATCGAGGGCGACCAGAAATTCCCAGCTTCTGGCTCAACCACCAGGGCATCCAGATGGTGTGTGAGACGTTGACTGAGTGCTGGGACCACGACCCAGAGGCCCGTCTCACAGCCCAGTGTGTGGCAGAACGCTTCAGTGAGCTGGAGCATCTGGACAGGCTCTCGGGGAGGAGCTGCTCGGAGGAGAAGATTCCTGAAGACGGCTCCCTAAACACTACCAAATAG
ORF Protein Sequence MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSDVEMEAQKDEIICPSCNRTAHPLRHINNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-659 Pre-Made Dalutrafusp biosimilar, Whole mAb, Anti-TGFBR2 Antibody: Anti-AAT3/FAA3/LDS1B/LDS2/LDS2B/MFS2/RIIC/TAAD2/TBR-ii/TBRII/TGFR-2-RII therapeutic antibody
    Target Antibody GM-Tg-g-T49989-Ab Anti-TGFR2/ TGFBR2/ AAT3 monoclonal antibody
    Target Antigen GM-Tg-g-T49989-Ag TGFBR2 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T49989 transforming growth factor, beta receptor II (70/80kDa) (TGFBR2) protein & antibody
    ORF Viral Vector pGMLP001435 Human TGFBR2 Lentivirus plasmid
    ORF Viral Vector pGMLV002329 Human TGFBR2 Lentivirus plasmid
    ORF Viral Vector pGMLV002336 Human TGFBR2 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-041 Human TGFBR2 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-181 Human TGFBR2 Adenovirus plasmid
    ORF Viral Vector pGMPC000634 Human TGFBR2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001435 Human TGFBR2 Lentivirus particle
    ORF Viral Vector vGMLV002329 Human TGFBR2 Lentivirus particle
    ORF Viral Vector vGMLV002336 Human TGFBR2 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-041 Human TGFBR2 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-181 Human TGFBR2 Adenovirus particle


    Target information

    Target ID GM-T49989
    Target Name TGFBR2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7048
    Gene ID 100033860 (Equus caballus), 101091725 (Felis catus), 21813 (Mus musculus), 477039 (Canis lupus familiaris)
    535376 (Bos taurus), 703088 (Macaca mulatta), 7048 (Homo sapiens), 81810 (Rattus norvegicus)
    Gene Symbols & Synonyms TGFBR2,Tgfbr2,TGFBRII,TBETA-RII,DNIIR,RIIDN,TBR-II,TbetaRII,TbetaR-II,1110020H15Rik,AAT3,FAA3,LDS2,MFS2,RIIC,LDS1B,LDS2B,TAAD2,TBRII,TBR-ii,TGFR-2,tbetaR-II,TGFbeta-RII,Tgfbr2T,TGF-beta 2
    Target Alternative Names 1110020H15Rik,AAT3,DNIIR,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,RIIDN,TAAD2,TBETA-RII,TBR-II,TBR-ii,TBRII,TGF-beta 2,TGF-beta receptor type-2,TGF-beta type II receptor,TGFBR2,TGFBRII,TGFR-2,TGFbeta-RII,TbetaR-II,TbetaR-II),TbetaRII,Tgfbr2,Tgfbr2T,Transforming growth factor-beta receptor type II (TGF-beta receptor type II,tbetaR-II
    Uniprot Accession P37173,P38438,Q62312
    Additional SwissProt Accessions: Q62312,P37173,P38438
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease cancer
    Disease from KEGG MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, Cellular senescence, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling pathway, Adherens junction, Th17 cell differentiation, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Chagas disease, Hepatitis B, Human T-cell leukemia virus 1 infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Chronic myeloid leukemia, Hepatocellular carcinoma, Gastric cancer
    Gene Ensembl ENSECAG00000015269, ENSMUSG00000032440, ENSCAFG00845022794, ENSBTAG00000019832, ENSMMUG00000010031, ENSG00000163513
    Target Classification Cytokine Receptor, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.